- Properties of GST-CALM expressed in E. coli
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Kim JA, Kim SR, Jung YK, Woo SY, Seoh JY, Hong YS, Kim HL
- KMID: 1109309
- Exp Mol Med.
- 2000 Jun;32(2):93-99.
Clathrin-coated vesicles (CCVs) are involved in protein and lipid trafficking between intracellular compartments in eukaryotic cells. CCVs are composed of clathrin and assembly proteins. The clathrin assembly protein lymphoid... -
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- An antibody reactive to the Gly63-Lys68 epitope of NT-proBNP exhibits O-glycosylation-independent binding
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Lee Y, Kim H, Chung J
- KMID: 2155379
- Exp Mol Med.
- 2014 Sep;46(9):e114.
- doi: 10.1038/emm.2014.57
The N-terminal fragment of prohormone brain natriuretic peptide (NT-proBNP) is a commonly used biomarker for the diagnosis of congestive heart failure, although its biological function is not well known. NT-proBNP... -
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- T-CAM, a fastatin-FIII 9-10 fusion protein, potently enhances anti-angiogenic and anti-tumor activity via alphavbeta3 and alpha5beta1 integrins
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Nam JO, Jung MY, Thapa N, Lee BH, Park RW, Kim IS
- KMID: 1052942
- Exp Mol Med.
- 2008 Apr;40(2):196-207.
- doi: 10.3858/emm.2008.40.2.196
We made fusion protein of fastatin and FIII 9-10, termed tetra-cell adhesion molecule (T-CAM) that can interact simultaneously with alphavbeta3 and alpha5beta1 integrins, both playing important roles in tumor angiogenesis.... -
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- Characterization and epitope mapping of two monoclonal antibodies against human CD99
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Gil MC, Lee MH, Seo JI, Choi YL, Kim MK, Jung KC, Park SH, Kim TJ
- KMID: 1121094
- Exp Mol Med.
- 2002 Dec;34(6):411-418.
CD99 plays an critical role in the diapedesis of monocytes, T cell differentiation, and the transport of MHC molecules. Engagement of CD99 by agonistic monoclonal antibodies has been reported... -
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- Recombinant tetra-cell adhesion motifs supports adhesion, migration and proliferation of keratinocytes/fibroblasts, and promotes wound healing
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Jung MY, Thapa N, Kim JE, Yang JD, Cho BC, Kim IS
- KMID: 1090969
- Exp Mol Med.
- 2007 Oct;39(5):663-672.
An extracellular matrix protein plays an important role in skin wound healing. In the present study, we engineered a recombinant protein encompassing the 9th and 10th type III domains of... -
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- Expression and characterization of the flavoprotein domain of gp91phox
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Han CH, Lee MH
- KMID: 1103470
- J Vet Sci.
- 2000 Jun;1(1):19-26.
Truncated forms of gp91(phox) were expressed in E. coli in which the N-terminal hydrophobic transmembrane region was replaced with a portion of the highly soluble bacterial protein thioredoxin (TRX). TRX-gp91(phox)... -
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- Expression of Translationally Controlled Tumor Protein (TCTP) Gene of Dirofilaria immitis Guided by Transcriptomic Screening
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Fu Y, Lan J, Wu X, Yang D, Zhang Z, Nie H, Hou R, Zhang R, Zheng W, Xie Y, Yan N, Yang Z, Wang C, Luo L, Liu L, Gu X, Wang S, Peng X, Yang G
- KMID: 1715666
- Korean J Parasitol.
- 2014 Feb;52(1):21-26.
- doi: 10.3347/kjp.2014.52.1.21
Dirofilaria immitis (heartworm) infections affect domestic dogs, cats, and various wild mammals with increasing incidence in temperate and tropical areas. More sensitive antibody detection methodologies are required to diagnose asymptomatic... -
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- Homo-dimerization of RyR1 C-terminus via charged residues in random coils or in an alpha-helix
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Lee EH, Allen PD
- KMID: 1090962
- Exp Mol Med.
- 2007 Oct;39(5):594-602.
To investigate the mechanism by which the C-terminus (4,938-5,037) of the ryanodine receptor 1 (RyR1) homo-tetramerizes, forming a functional Ca2+ -release channel, the structural requirements for the tetramerization were studied... -
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- Serum immunoglobulin fused interferon-alpha inhibited tumor growth in athymic mice bearing colon 26 adenocarcinoma cells
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Kim JS, Yu KN, Noh MS, Woo MA, Park SJ, Park JH, Hua J, Cho HS, Hwang SK, Lee ES, Chung YS, Choi IY, Kwon SC, Cho MH
- KMID: 1102953
- J Vet Sci.
- 2008 Mar;9(1):45-50.
- doi: 10.4142/jvs.2008.9.1.45
Interferon (IFN) has therapeutic potential for a wide range of infectious and proliferative disorders. However, the half-life of IFN is too short to have a stable therapeutic effect. To overcome... -
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