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Protein Expression of Cyclin B1, Transferrin Receptor, and Fibronectin Is Correlated with the Prognosis of Adrenal Cortical Carcinoma

Moon SJ, Kim JH, Kong SH, Shin CS

BACKGROUND: Adrenal cortical carcinoma (ACC) is a rare cancer with a variable prognosis. Several prognostic factors of ACC have been previously reported, but a proteomic analysis has not yet been...
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Hepcidin and iron parameters in children with anemia of chronic disease and iron deficiency anemia

Mahajan G, Sharma S, Chandra J, Nangia A

BACKGROUND: Anemia of chronic disease (ACD) and iron deficiency anemia (IDA) are the two most prevalent forms of anemia having interrelated characteristics. Hepcidin, a newly introduced biomarker for assessment of...
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Iron Supplementation Reverses the Reduction of Hydroxymethylcytosine in Hepatic DNA Associated With Chronic Alcohol Consumption in Rats

Tammen SA, Park JE, Shin PK, Friso S, Chung J, Choi SW

BACKGROUND: Alcohol is known to affect two epigenetic phenomena, DNA methylation and DNA hydroxymethylation, and iron is a cofactor of ten-eleven translocation (TET) enzymes that catalyze the conversion from methylcytosine...
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The usefulness of soluble transferrin receptor in the diagnosis and treatment of iron deficiency anemia in children

Yoon SH, Kim DS, Yu ST, Shin SR, Choi DY

PURPOSE: Soluble transferrin receptor (sTfR) is a truncated extracellular form of the membrane transferrin receptor produced by proteolysis. Concentrations of serum sTfR are related to iron status and erythropoiesis in...
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Iron Deficiency Anemia in Infants and Young Children

Lim JY

The etiology of iron deficiency anemia (IDA) in infancy (9-24 months) are diet, parasite, blood loss and Helicobacter pylori. Diet is the most common etiology of IDA in infancy. If...
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Serum hepcidin levels and iron parameters in children with iron deficiency

Choi HS, Song SH, Lee JH, Kim HJ, Yang HR

BACKGROUND: Iron deficiency (ID) and iron deficiency anemia (IDA) are common nutritional disorders in children. Hepcidin, a peptide hormone produced in the liver, is a central regulator of systemic iron...
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Relationship between Helicobacter pylori infection and iron-deficiency anemia in infants and children

Son MH, Yeom JS, Park JS, Park ES, Seo JH, Lim JY, Park CH, Woo HO, Youn HS

PURPOSE: To elucidate a potential association between Helicobacter pylori (HP) infection and iron-deficiency anemia (IDA) in infants and children in terms of the other factors related to iron utilization and...
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Correlaton between soluble transferrin receptor concentration and inflammatory markers

Kim SY, Son MH, Yeom JS, Park JS, Park ES, Seo JH, Lim JY, Park CH, Woo HO, Youn HS

PURPOSE: The concentration of soluble transferrin receptor (sTfR) is estimated as an iron parameter to evaluate erythropoiesis and iron status. The aim of our study is to evaluate the correlation...
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Detection of Transferrin Receptor Over-Expression in a Rodent Model of Myocardial Ischemia/Reperfusion Injury Using Novel 99mTc Transferrin Conjugates: A Pilot Study

Jeong HJ, Kim EM, Kim NH, Lee CM, Cheong SJ, Kim DW, Lim ST, Yoon KJ, Nah JW, Sohn MH

BACKGROUND AND OBJECTIVES: Reperfusion of ischemic myocardium is necessary to salvage tissue from eventual death. However, new pathophysiological changes are initiated after reperfusion. The aim of this study was to...
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The Usefulness of the Serum Transferrin Receptor to Serum Ferritin Ratio for Discriminating between Iron Deficiency Anemia and Anemia of Inflammation in Infants

Park ES, Kim IS, Jun JS, Seo JH, Lim JY, Park CH, Woo HO, Youn HS

BACKGROUND: The incidence of iron deficiency anaemia in infants, which is caused by the increased iron demand for rapid growth during this period, is reported to range from 10 to...
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Maternal serum iron-related parameters in severe preeclampsia

Kwon I, Kwon JY, Lee JK

  • KMID: 2273157
  • Korean J Obstet Gynecol.
  • 2007 Aug;50(8):1064-1070.
OBJECTIVE: Based on the pathophysiology of preeclampsia and the hypothesis that the iron was a catalyzer of the oxidative stress and lipid peroxidation and that the ferritin and soluble transferrin...
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Cytotoxicity of OKT9 ScFv-Diphtheria Toxin Fusion Immunotoxin on Human Brain Tumor Cell Lines

Back OK, Song YJ, Lee HW, Park NH, Kim YC, Seo SY, Kim KU

  • KMID: 1905019
  • J Korean Neurosurg Soc.
  • 2004 Jul;36(1):59-65.
OBJECTIVE: Immunotoxin therapy is a novel approach for the treatment of tumor, and it has been successfully used in the central nervous system. The purpose of this study is to...
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Diagnostic Availability of the Soluble Transferrin Receptor in Old Patients with Iron Deficiency Anemia and Anemia of Chronic Renal Failure

Lee MH

  • KMID: 1730178
  • Korean J Lab Med.
  • 2004 Apr;24(2):80-86.
BACKGROUND: The diagnostic efficiency of soluble transferrin receptor (sTfR) was investigated to detect iron deficiency among old patients with iron deficiency anemia (IDA) and anemia of chronic renal failure (CRF)....
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Comparison between Soluble Transferrin Receptor, Serum Ferritin and Trans-ferrin Saturation in Chronic Renal Failure Patients

Cho HS, Lee CH, Kim KD

  • KMID: 1730211
  • Korean J Lab Med.
  • 2004 Oct;24(5):267-272.
BACKGROUND: In chronic renal failure (CRF) patients, iron deficiency is a common problem and a primary cause of resistance to recombinant human erythropoietin (rHuEPO) therapy. Serum ferritin and transferrin saturation...
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Iron Status of the Adolescent Females before and after Menarche

Lim HS, Jeong ES

  • KMID: 2269680
  • Korean J Nutr.
  • 2003 Jul;36(6):646-652.
This study was performed to determine the iron status of the adolescent Korean girls before and after menarche. The 101 subjects aged 11-13 years who attending in an elementary school...
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Iron Parameters and Soluble Transferrin Receptor in Neonates

Oh CH, Namgung R, Park MS, Park KI, Lee C

  • KMID: 2144555
  • J Korean Soc Neonatol.
  • 2003 Nov;10(2):185-192.
PURPOSE: Serum soluble transferrin receptor (sTfR) is a marker of iron deficiency and erythropoiesis. The purpose of this study is to evaluate the changes of iron parameters and sTfR in...
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Defective Erythropoiesis in Bone Marrow is a Mechanism of Anemia in Children with Cancer

Kim MH, Lee JH, Wu CW, Cho SW, Lee KC

Evaluation of the mechanism of anemia in cancer patients might help to select patients for the more efficient use of erythropoietin (EPO, a growth factor for erythroid precursor cells). For...
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Change of Erythropoiesis and Serum Transferrin Receptor Levels with Gestational Age in Healthy Pregnant Women

Choi JW, Im MW, Pai SH

  • KMID: 2083412
  • Korean J Hematol.
  • 2000 May;35(2):134-142.
BACKGROUND: To investigate the change of iron dynamics, erythropoiesis, and serum transferrin receptor (sTfR) concentration during pregnancy, we measured the reticulocyte subpopulations, reticulocyte maturity index (RMI) and sTfR concentration in...
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Diagnostic availability of the soluble transferrin receptor in iron deficiency anemia and anemia of chronic disease

Yang SE, Park CJ, Min WK, Chi HS

  • KMID: 2225925
  • Korean J Clin Pathol.
  • 2000 Apr;20(2):119-125.
BACKGROUND: In diagnoses of iron deficiency anemia(IDA) and anemia of chronic disease(ACD), bone marrow examinations, the gold standard, are too invasive. Iron parameters such as serum ferritin, iron, and total...
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Influence of Iron Depletion on Immature Reticulocyte Fractions and Reticulocyte Maturity Index

Choi JW, Pai SH

  • KMID: 2055423
  • J Clin Pathol Qual Control.
  • 2000 Dec;22(2):235-241.
BACKGROUND: To investigate the influence of body iron status on immature reticulocyte fractions and reticulocyte maturity index (RMI), We measured serum iron markers, fluorescent intensity of reticulocytes, and serum transferrin...
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