- Somatostatin Receptor
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Kim E, Sohn S, Lee M, Park H, Jung J, Park S
- KMID: 2200376
- J Korean Soc Endocrinol.
- 2003 Aug;18(4):342-355.
No abstract available. -
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- Somatostatin Receptor Scintigraphy
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Bae SK
- KMID: 1556299
- Korean J Nucl Med.
- 1999 Feb;33(1):11-27.
Peptide imaging is a new diagnostic modality in nuclear medicine. 111In-pentetreotide (OctreoscanR) is the first commercially available peptide radiopharmaceutical. This review article presents the RESULTS of previous studies using 111In-pentetreotide... -
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- A Case of Zollinger-Ellison Syndrome with Gastrinoma Localized by 111In-Pentetreotide Scan
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Jeong HJ, Ryu JS, Kim JS, Moon DH, Jung HY, Ha HK, Lee HK
- KMID: 2038082
- Korean J Nucl Med.
- 1999 Dec;33(6):537-542.
In patient with Zollinger-Ellison syndrome, it is difficult to localize gastrinoma because the tumor is frequently small and multiple. However, accurate localization of the tumor is important for the treatment.... -
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- Somatostatin Receptors in Lung Cancer: From Function to Molecular Imaging and Therapeutics
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Callison J, Walker RC, Massion PP
- KMID: 2005737
- J Lung Cancer.
- 2011 Dec;10(2):69-76.
- doi: 10.6058/jlc.2011.10.2.69
Lung cancer is a deadly disease that is difficult to diagnose and even more difficult to treat effectively. Many pathways are known to affect tumor growth, and targeting these pathways... -
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- Review of Radionuclide Treatment for Neuroendocrine Tumors
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Jeong HJ
- KMID: 2313018
- Nucl Med Mol Imaging.
- 2006 Apr;40(2):90-95.
Neuroendocrine tumors (NETs) consist of a heterogeneous group of tumors that are able to uptake neuroamine and/or specific receptors, such as somatostatin receptors, which can play important roles of the... -
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- Immunoreactivity of Somatostatin Receptor Subtype 2 in Dorsal Root Ganglia in the Rat
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Noh KC, Chung YK, Yoo JH, Park JS, Lee JD, Kang MC, Won MH, Kang TC, Park SK
- KMID: 2106037
- J Korean Orthop Assoc.
- 2004 Feb;39(1):88-93.
PURPOSE: Somatostatin has been suggested to play a role in the transmission of neurotransmitters and in the modulation of pain. Of the different subtypes of somatostatin receptors 2, sstr2A and... -
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- Lu-177-Based Peptide Receptor Radionuclide Therapy for Advanced Neuroendocrine Tumors
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Kim K, Kim SJ
- KMID: 2414811
- Nucl Med Mol Imaging.
- 2018 Jun;52(3):208-215.
- doi: 10.1007/s13139-017-0505-6
Peptide receptor radionuclide therapy (PRRT) is a systemic cytotoxic radiation therapy using a compound of β-emitting radionuclide chelated to a peptide for the treatment of tumor with overexpressed specific cell... -
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- Differential Expression of Somatostatin Receptor Subtype 2 in Dorsal Root Ganglia after Ischemic Injury in the Rat
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Noh KC, Chung YK, Yoo JH, Jang WS, Lee JD, Won MH
- KMID: 1901405
- J Korean Orthop Assoc.
- 2004 Dec;39(7):736-744.
PURPOSE: The somatostatin has been suggested to play a role in the transmission of neurotransmitters and the modulation of pain. Therefore, this study was carried out to investigate the spatial... -
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- Neuroendocrine Regulation of Growth Hormone Secretion
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Park S
- KMID: 2192845
- J Korean Soc Pediatr Endocrinol.
- 2010 Dec;15(3):151-156.
The regulation of growth hormone (GH) secretion is, to a larger extent, controlled by three hypothalamic hormones: GH-releasing hormone (GHRH), somatostatin, and ghrelin. Each binds to G protein-linked membrane receptors... -
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- Clinical Significance of Protein Expression of Cyclooxygenase-2 and Somatostatin Receptors in Gastroenteropancreatic Neuroendocrine Tumors
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Kim HS, Lee HS, Kim WH
- KMID: 2167556
- Cancer Res Treat.
- 2011 Sep;43(3):181-188.
PURPOSE: This study was undertaken to evaluate the significance of cyclooxygenase-2 (COX2) overexpression and the expression of somatostatin receptor (SSTR) subtypes in gastroenteropancreatic neuroendocrine tumors (GEP-NETs). MATERIALS AND METHODS: Two hundred... -
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- Ga-68 Somatostatin Receptor PET/CT in von Hippel-Lindau Disease
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Oh JR, Kulkarni H, Carreras C, Schalch G, Min JJ, Baum RP
- KMID: 2052010
- Nucl Med Mol Imaging.
- 2012 Jun;46(2):129-133.
Von Hippel-Lindau (VHL) disease is a dominantly inherited familial cancer syndrome with a variety of benign and malignant tumors such as retinal and central nervous system hemangioblastomas, endolymphatic sac tumors,... -
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- Therapeutic Effect of a Novel Chimeric Molecule Targeting Both Somatostatin and Dopamine Receptors on Growth Hormone-Secreting Pituitary Adenomas
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Kim J, Oh JH, Harlem H, Culler MD, Ku CR, Lee EJ
- KMID: 2471734
- Endocrinol Metab.
- 2020 Mar;35(1):177-187.
- doi: 10.3803/EnM.2020.35.1.177
BACKGROUND: Acromegaly is a rare disease primarily caused by growth hormone (GH)-secreting pituitary adenomas, and its treatment is costly. Moreover, some patients are unresponsive to treatment. Hence, there are increasing... -
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- SSTR2A Protein Expression in Neuroendocrine Neoplasms of the Colorectum
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Kim YE, Lee J, Park YS, Kim KM
- KMID: 1443733
- Korean J Pathol.
- 2011 Jun;45(3):276-280.
- doi: 10.4132/KoreanJPathol.2011.45.3.276
BACKGROUND: Expression studies of somatostatin receptor type 2A (SSTR2A) in neuroendocrine neoplasms (NENs) led to the development of clinically relevant diagnostic and therapeutic strategies. However, most of these strategies used... -
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- Effect of Gs alpha Gene Mutation on the Expression of the Rat Somatostatin Receptor Gene
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Yang IM, Park SJ, Jhang HG, Lee GJ, Oh SJ, Kim SW, Kim JW, Kim YS, Choi YK
- KMID: 2199560
- J Korean Soc Endocrinol.
- 1999 Dec;14(4):657-666.
BACKGROUND: The growth hormone (GH)-secreting pituitary adenoma with mutation of Gs alpha gene (gsp oncogene) is known to show a higher response to somatostatin. The mechanism for the higher response... -
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- Modulation of Pituitary Somatostatin Receptor Subtype (sst1-5) mRNA Levels by Growth Hormone (GH) -Releasing Hormone in Purified Somatotropes
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Park S, Park H, Lee M, Sohn S, Kim E, Jung J, Frohman LA, Kineman RD
- KMID: 2285276
- Korean J Physiol Pharmacol.
- 2003 Apr;7(2):79-84.
We have previously reported that expression of the somatostatin receptor subtypes, sst1-5, is differentially regulated by growth hormone (GH) -releasing hormone (GHRH) and forskolin (FSK), in vitro. GHRH binds to... -
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- Two cases of 111Indium Pentetreotide Scan for the Pre- and Post-Operative Evaluation of Localization and Metastasis in Medullary Thyroid Carcinoma
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Chung JH, Kim KW, Ahn KJ, Min YK, Lee MS, Lee MK, Kim KA, Kim YS, Koh EM
- KMID: 2461608
- J Korean Soc Endocrinol.
- 1996 Mar;11(1):85-92.
Medullary carcinoma of the thyroid gland(MTC) constitutes approximatesly 3% to 10% of all malignant thyroid tumors. It appears in both familial and sporadic forms. Metastases are frequently present at diagnosis... -
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- Changes in Somatostatin Receptor mRNA Levels by G Protein Mutation in GH3 Cells Which Show Responsiveness to Growth Hormone-Releasing Hormone
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Kim EH, Sohn SJ, Lee MA, Seo SH, Ju SH, Lee D, Chung HJ, Jung JC, Park SJ
- KMID: 2100463
- J Korean Soc Endocrinol.
- 2005 Aug;20(4):323-333.
- doi: 10.3803/jkes.2005.20.4.323
BACKGROUNDS: GH3 cells lack growth hormone(GH)-releasing hormone(GHRH) receptors. In this study, GH3 cells permanently transfected with human GHRH receptor cDNA(GH3-GHRHR cells), were established in order to examine the effects of... -
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- Neuroendocrine Tumors
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Park YS
- KMID: 2267784
- Korean J Med.
- 2013 Oct;85(4):354-356.
Neuroendocrine tumors (NETs) are rare. However, several data showed the incidence is increased in the past 30 years. NETs can be both functional and non-functional, and may be undetected for... -
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- Gene Expression of Somatostatin Receptor Subtype 2 and 5 in GH-Secreting Pituitary Adenomas
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Kim SW, Kim JW, Kim YS, Choi YK, Park SJ, Yang IM, Woo JT, Kim KK
- KMID: 2331077
- J Korean Soc Endocrinol.
- 1997 Dec;12(4):508-517.
BACKGROUND: SSTR2 and SSTR5 are most frequently observed in GH-secreting pituitary tumors, and SSTR5 is believed to be more specific to mammosomatotroph lineage. Octreotide binds with high affinity to those... -
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- Incidental Detection of Parathyroid Adenoma on Somatostatin Receptor PET/CT and Incremental Role of ¹â¸F-Fluorocholine PET/CT in MEN1 Syndrome
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Arora S, Damle NA, Passah A, Yadav MP, Ballal S, Aggarwal V, Gupta Y, Kumar P, Tripathi M, Bal C
- KMID: 2414816
- Nucl Med Mol Imaging.
- 2018 Jun;52(3):238-242.
- doi: 10.1007/s13139-018-0520-2
Multiple endocrine neoplasia type 1 (MEN1) syndrome is characterized by combined occurrence of tumors of endocrine glands including the parathyroid, the pancreatic islet cells, and the anterior pituitary gland. Parathyroid... -
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