- Expression of the ATP-gated P2X7 Receptor on M Cells and Its Modulating Role in the Mucosal Immune Environment
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Kim SH, Lee HY, Jang YS
- KMID: 2150829
- Immune Netw.
- 2015 Feb;15(1):44-49.
- doi: 10.4110/in.2015.15.1.44
Interactions between microbes and epithelial cells in the gastrointestinal tract are closely associated with regulation of intestinal mucosal immune responses. Recent studies have highlighted the modulation of mucosal immunity by... -
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- Participation of Central P2X7 Receptors in CFA-induced Inflammatory Pain in the Orofacial Area of Rats
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Yang KY, Kim MD, Ju JS, Kim MJ, Ahn DK
- KMID: 1703491
- Int J Oral Biol.
- 2014 Mar;39(1):49-56.
We investigated the role of central P2X receptors in inflammatory pain transmission in the orofacial area in rats. Experiments were carried out using male Sprague-Dawley rats weighing 230-280g. Complete Freund's... -
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- P2X7 Receptor Expression in Coexistence of Papillary Thyroid Carcinoma with Hashimoto's Thyroiditis
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Kwon JH, Nam ES, Shin HS, Cho SJ, Park HR, Kwon MJ
- KMID: 1875755
- Korean J Pathol.
- 2014 Feb;48(1):30-35.
BACKGROUND: This study was aimed at investigating the relation of P2X7 receptor (P2X7R) expression with the clinicopathological features of papillary thyroid carcinoma (PTC) coexisting with Hashimoto's thyroiditis (HT). METHODS: We examined... -
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- P2X7 Receptor-mediated Membrane Blebbing in Salivary Epithelial Cells
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Hwang SM, Koo NY, Choi SY, Chun GS, Kim JS, Park K
- KMID: 2071668
- Korean J Physiol Pharmacol.
- 2009 Jun;13(3):175-179.
- doi: 10.4196/kjpp.2009.13.3.175
High concentrations of ATP induce membrane blebbing. However, the underlying mechanism involved in epithelial cells remains unclear. In this study, we investigated the role of the P2X7 receptor (P2X7R) in... -
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- Effects of Brilliant Blue G on Serum Tumor Necrosis Factor-alpha Levels and Depression-like Behavior in Mice after Lipopolysaccharide Administration
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Ma M, Ren Q, Zhang JC, Hashimoto
- KMID: 2171126
- Clin Psychopharmacol Neurosci.
- 2014 Apr;12(1):31-36.
OBJECTIVE: Accumulating evidence suggests that inflammation plays a role in the pathophysiology of major depression. The adenosine triphosphate (ATP)-sensitive P2X7 receptor (P2X7R) plays a crucial role in microglial activation caused... -
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- Microglial P2X7 receptor expression is accompanied by neuronal damage in the cerebral cortex of the APPswe/PS1dE9 mouse model of Alzheimer's disease
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Lee HG, Won SM, Gwag BJ, Lee YB
- KMID: 991618
- Exp Mol Med.
- 2011 Jan;43(1):7-14.
- doi: 10.3858/emm.2011.43.1.001
The possibility that P2X7 receptor (P2X7R) expression in microglia would mediate neuronal damage via reactive oxygen species (ROS) production was examined in the APPswe/PS1dE9 mouse model of Alzheimer's disease (AD).... -
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- Antidepressant-like Effects Induced by Chronic Blockade of the Purinergic 2X7 Receptor through Inhibition of Non-like Receptor Protein 1 Inflammasome in Chronic Unpredictable Mild Stress Model of Depression in Rats
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Aricioglu , Ozkartal C, Bastaskin , Tüzün E, Kandemir C, Sirvanci S, Kucukali C, Utkan T
- KMID: 2456729
- Clin Psychopharmacol Neurosci.
- 2019 Mar;17(2):261-272.
- doi: 10.9758/cpn.2019.17.2.261
OBJECTIVE: Purinergic 2X7 receptor (P2X7R) activation is known to be involved in pathogenesis of depression. Our aims were to investigate P2X7R-activated inflammasome pathways in parallel with induction of depression and... -
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- Genetic Association for P2X7R rs3751142 and CARD8 rs2043211 Polymorphisms for Susceptibility of Gout in Korean Men: Multi-Center Study
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Lee SW, Lee SS, Oh DH, Park DJ, Kim HS, Choi JR, Chae SC, Yun KJ, Chung WT, Choe JY, Kim SK
- KMID: 2468246
- J Korean Med Sci.
- 2016 Oct;31(10):1566-1570.
- doi: 10.3346/jkms.2016.31.10.1566
The aim of this study was to determine the association between P2X7R rs3751142 and CARD8 rs2043211 polymorphisms and gout susceptibility in male Korean subjects. This study enrolled a total of... -
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