- Expression of Neurokinin 1 Receptor in Allergic Rhinitis
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Lee DJ, Lee HM, Lee SH, Hwang SJ
- KMID: 1923200
- Korean J Otolaryngol-Head Neck Surg.
- 2001 Dec;44(12):1298-1302.
BACKGROUND AND OBJECTIVES: In airway tissues, the substance P has been suggested as the neurotransmitter in the afferent sensory nerve which responds to various irritants and that it may be... -
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- Efficacy of the oral neurokinin-1 receptor antagonist aprepitant administered with ondansetron for the prevention of postoperative nausea and vomiting
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Lim CS, Ko YK, Kim YH, Park SI, Kim JK, Kim MJ, Kim HJ
- KMID: 1767329
- Korean J Anesthesiol.
- 2013 Mar;64(3):212-217.
- doi: 10.4097/kjae.2013.64.3.212
BACKGROUND: 5-HT3 receptor antagonist, dexamethasone and droperidol were used for the prevention of postoperative nausea and vomiting (PONV). Recently, neurokinin-1 (NK1) antagonist has been used for PONV. We evaluated the... -
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- Electrophysiological study on the modulation of uterine mechanoreceptor by substance P
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Na JY, Chang KH, Shin JC, You SW, Hong SC, Lee SE, Han HC
- KMID: 2076230
- Korean J Obstet Gynecol.
- 2001 Apr;44(4):740-747.
OBJECTIVE: In inflammation, hyperalgesia is a common phenomenon but its mechanism has not been clarified. Recently some reports suggested substance P might be important factors for inflammatory hyperalgesia in somatic... -
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- Expression of Neuropeptides and Their Receptors in Melasma
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Lee HJ, Bak H, Chang SE, Choi JH, Kim MN, Kim BJ
- KMID: 2248294
- Korean J Dermatol.
- 2008 May;46(5):627-632.
BACKGROUND: The pathogenesis of melasma has not yet been clearly demonstrated. But, clinical manifestations such as remarkable lesional symmetry and the distribution related to trigeminal nerves, suggest that the neural... -
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- Allopregnanolone suppresses mechanical allodynia and internalization of neurokinin-1 receptors at the spinal dorsal horn in a rat postoperative pain model
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Fujita M, Fukuda T, Sato Y, Takasusuki T, Tanaka M
- KMID: 2400903
- Korean J Pain.
- 2018 Jan;31(1):10-15.
- doi: 10.3344/kjp.2018.31.1.10
BACKGROUND: To identify a new strategy for postoperative pain management, we investigated the analgesic effects of allopregnanolone (Allo) in an incisional pain model, and also assessed its effects on the... -
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- The effect of aprepitant for the prevention of postoperative nausea and vomiting in patients undergoing gynecologic surgery with intravenous patient controlled analgesia using fentanyl: aprepitant plus ramosetron vs ramosetron alone
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Lee SJ, Lee SM, Kim SI, Ok SY, Kim SH, Park SY, Kim MG
- KMID: 2236271
- Korean J Anesthesiol.
- 2012 Sep;63(3):221-226.
- doi: 10.4097/kjae.2012.63.3.221
BACKGROUND: The purpose of this study was to evaluate the effect of an aprepitant, neurokinin-1(NK1) receptor antagonist, for reducing postoperative nausea and vomiting (PONV) for up to 24 hours in... -
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- The Effect of NK-1 Receptor Antagonist on the Enhanced Response to Bradykinin by Mustard Oil Treatment of the Rat Uterus
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Na JY, Park JW, Hong SK
- KMID: 2272095
- Korean J Obstet Gynecol.
- 2003 Jul;46(7):1325-1331.
OBJECTIVE: To find out wheather the substance P takes part in the pain mediating system of uterus, and to ascertain the role of substance P in the hypersensitivity of hypogastric... -
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- The Effects of Substance P on the Proliferation Capability of Cultured Human Keratinocytes
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Suh HS, Chang SE, Park EM, Choi JH, Sung KJ
- KMID: 2303308
- Korean J Dermatol.
- 1998 Aug;36(4):595-601.
BACKGROUND: Recent evidence indicates that neurokinins released from cutaneous C-fibers can function as inflammatory mediators by activating cells of the immune system such as lymphocytes, monocytes and mast cells. Substance... -
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- Comparison of Tight Junction Protein-Related Gene mRNA Expression Levels between Male and Female Gastroesophageal Reflux Disease Patients
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Kim JJ, Kim N, Park JH, Kim YS, Lee SM, Lee DH, Jung HC
- KMID: 2417307
- Gut Liver.
- 2018 Jul;12(4):411-419.
- doi: 10.5009/gnl17419
BACKGROUND/AIMS: Male predominance has been observed in the erosive reflux disease (ERD), but reverse finding in nonerosive reflux disease (NERD). This suggests sex-specific medicine approach is needed but its mechanism... -
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- Effect of Antidromic Impulses on the Mechanical Allodynia in a Rat Model of Peripheral Neuropathic Pain
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Shin JW, Hahm KD, Leem JW, Park SH, Choi Y, Jung WS, Lee C
- KMID: 1947093
- J Korean Pain Soc.
- 2003 Jun;16(1):14-22.
BACKGROUND: Nerve impulses that are transmitted, antidromically, into peripheral terminals, following nerve injury, may be a factor in neuropathic pain. The present study was designed to investigate the effects of... -
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