- IL-4/IL-13 Cytokine and Receptor in Asthma
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Yang ES
- KMID: 2314355
- Pediatr Allergy Respir Dis.
- 2005 Mar;15(1):1-11.
Asthma is a chronic allergic inflammatory disease of lung. The initiation and progression of asthma is dependent on the cytokines interleukin (IL) -4 and IL-13 acting through related receptor complexes.... -
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- Interleukin-4 Receptor Expression on Human Renal Cell Carcinoma Cell Lines by a Reverse Transcription-Polymerase Chain Reaction
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Cheon J, Chung DJ, Choi JB, Koh SK, Sohn JW
- KMID: 1913970
- Korean J Urol.
- 1995 Feb;36(2):121-127.
Recently interleukin-4 (IL-4) has been suggested to be a promising therapeutic agent for the malignant tumors of both murine and human origin. The effect of IL-4 is mediated by IL-4... -
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- Essential roles for ID-1 motif of interleukin-4 receptor alpha chain in interleukin-4 signaling
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Youn J, Lee KH, Hwang WY, Paik DJ, Chung HS
- KMID: 2285854
- J Asthma Allergy Clin Immunol.
- 2003 Jun;23(2):372-384.
BACKGROUND: Interleukin (IL)-4 is a pleiotropic cytokine that plays an important role in the pathogenesis of the allergic inflammation and asthma. Upon IL-4 receptor (IL-4R) engagement, a variety of signaling... -
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- A Study of Susceptibility between Allergic Rhinitis and IL-4 Receptor alpha Gene Polymorphism Study in Korean
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Lee JH, Choi TW, Lee JH, Lee SH, Jeong HM, Min JY, Kim JJ
- KMID: 2276463
- Korean J Otolaryngol-Head Neck Surg.
- 2005 Aug;48(8):1004-1007.
BACKGROUND AND OBJECTIVES: The IL-4 receptor (IL-4R) gene has been suggested as a candidate gene for atopic diseases. The IL-4R consists of two subunits: the alpha chain (IL-4Ralpha), which is... -
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- Association of IL-4, IL-4 Receptor alpha Polymorphisms and Gene-gene Interaction in Atopic Asthma
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- KMID: 2234223
- Korean J Asthma Allergy Clin Immunol.
- 2004 Dec;24(4):385-393.
BACKGROUND: Atopy is a major risk factor in the development of asthma. Interleukin (IL)-4 and the IL-4 receptor alpha (IL-4R alpha ) play crucial roles for the binding and signal... -
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- IL-4 Receptor alpha Polymorphisms May Be a Susceptible Factor for Work-Related Respiratory Symptoms in Bakery Workers
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Hur GY, Ye YM, Koh DH, Kim SH, Park HS
- KMID: 2260280
- Allergy Asthma Immunol Res.
- 2013 Nov;5(6):371-376.
- doi: 10.4168/aair.2013.5.6.371
PURPOSE: The IL-4 and IL-4 receptor alpha (IL-4Ralpha) genes are the key candidate genes for atopy and asthma susceptibility. Exposure to wheat flour can cause IgE sensitization and respiratory symptoms... -
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