- Role of Ghrelin in the Pathophysiology of Gastrointestinal Disease
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Cheung CK, Wu JC
- KMID: 1806665
- Gut Liver.
- 2013 Sep;7(5):505-512.
Ghrelin is a 28-amino-acid peptide that plays multiple roles in humans and other mammals. The functions of ghrelin include food intake regulation, gastrointestinal (GI) motility, and acid secretion by the... -
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- Future Treatment of Constipation-associated Disorders: Role of Relamorelin and Other Ghrelin Receptor Agonists
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Mosińska , Zatorski H, Storr M, Fichna J
- KMID: 2433518
- J Neurogastroenterol Motil.
- 2017 Apr;23(2):171-179.
- doi: 10.5056/jnm16183
There is an unmet need for effective pharmacological therapies for constipation, a symptom that significantly deteriorates patients' quality of life and impacts health care. Ghrelin is an endogenous ligand for... -
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- Serum Ghrelin Concentrations in Type 2 Diabetes Mellitus
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Jang YS, Hwang DJ, Yang YJ, Park JH, Lee DY
- KMID: 1568601
- J Korean Soc Pediatr Endocrinol.
- 2004 Jun;9(1):59-65.
PURPOSE:Ghrelin is an endogenous ligand of the growth hormone secretagogue receptor, and stomach is the major site of ghrelin secretion. The purpose of this study is to compare the serum... -
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- The Changes of Plasma Ghrelin Levels After Exercise in Obese Women
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Kang EY, Kim MS, Park EH, Kim KJ, Lee DY
- KMID: 1520744
- J Korean Soc Pediatr Endocrinol.
- 2007 Dec;12(2):135-141.
PURPOSE: Ghrelin is the known orexigenic hormone as well as an endogenous ligand for the growth hormone secretagogue receptor and has been shown to be related with the regulation of... -
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- Expression of ghrelin and its receptor according to feeding state in rats
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Kim MS, Yoon CY, Park YJ, Park HK, Jin CJ, Park KH, Shin CS, Park KS, Kim SY, Cho BY, Lee HK
- KMID: 2177839
- J Korean Diabetes Assoc.
- 2002 Jun;26(3):169-178.
BACKGROUND: Ghrelin is a newly discovered gut peptide, produced mainly in the stomach, which is secreted into the circulating blood and acts on the hypothalamus and the pituitary gland. Although... -
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- Relationship between Serum Ghrelin and Insulin Resistance in Obese Children and Adolescents
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Kim SY, Shin JY, Jung MJ, Choi BM, Lee JH, Lee KH
- KMID: 1838798
- J Korean Soc Pediatr Endocrinol.
- 2005 Dec;10(2):211-217.
PURPOSE: Ghrelin, a 28-amino-acid peptide predominantly produced by the stomach, is endogenous ligand of growth hormone secretagogue receptor and potent stimulator of growth hormone. Ghrelin is also proposed to be... -
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- Plasma Ghrelin Levels and Its Relationship with Obesity in Obese Children
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Jo DS, Lee JU, Kim SY, Kim SJ, Kang CW, Hwang PH, Lee DY
- KMID: 1568748
- J Korean Soc Pediatr Endocrinol.
- 2004 Dec;9(2):179-185.
Background:Ghrelin is a new endogenous ligand for the growth hormone secretagogue receptor. It activates the release of growth hormone from the pituitary and it also participates in the regualtion of... -
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- Role of Glucocorticoids in Fasting-induced Changes in Hypothalamic and Pituitary Components of the Growth Hormone (GH)-axis
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Kim E, Seo S, Chung H, Park S
- KMID: 1486102
- Korean J Physiol Pharmacol.
- 2008 Oct;12(5):217-223.
- doi: 10.4196/kjpp.2008.12.5.217
To directly test if elevated glucocorticoids are required for fasting-induced regulation of growth hormone (GH)-releasing hormone (GHRH), GHRH receptors (GHRH-R) and ghrelin receptors (GHS-R) expression, male rats were bilaterally adrenalectomized... -
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- Leu72Met and Other Intronic Polymorphisms in the GHRL and GHSR Genes Are Not Associated with Type 2 Diabetes Mellitus, Insulin Resistance, or Serum Ghrelin Levels in a Saudi Population
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Joatar FE, Al Qarni A, Ali ME, Al Masaud , Shire AM, Das N, Gumaa K, Giha HA
- KMID: 2389817
- Endocrinol Metab.
- 2017 Sep;32(3):360-369.
- doi: 10.3803/EnM.2017.32.3.360
BACKGROUND: Ghrelin (GHRL), a gastric peptide encoded by the GHRL gene, is known to be involved in energy homeostasis via its G protein receptor, encoded by the growth hormone secretagogue... -
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- Gastroparesis and Functional Dyspepsia: A Blurring Distinction of Pathophysiology and Treatment
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Kim BJ, Kuo B
- KMID: 2433495
- J Neurogastroenterol Motil.
- 2019 Jan;25(1):27-35.
- doi: 10.5056/jnm18162
Gastroparesis and functional dyspepsia are 2 of the most common gastric neuromuscular disorders. These disorders are usually confused, having both similarities and differences. The pathophysiology of these disorders involves abnormal... -
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