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Brain-Region Specific Apoptosis Triggered by Eph/ephrin Signaling

Park S

Eph receptors and their ligands, ephrins, are abundantly expressed in neuroepithelial cells of the early embryonic brain. Overstimulation of Eph signaling in vivo increases apoptotic cell death of neuroepithelial cells,...
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Multiple Regulation of Roundabout (Robo) Phosphorylation in a Heterologous Cell System

Park HT

  • KMID: 1611238
  • Korean J Physiol Pharmacol.
  • 2004 Apr;8(2):111-115.
Roundabout (Robo) is the transmembrane receptor for slit, the neuronal guidance molecule. In this study, the tyrosine phosphorylation of Robo was observed in Robo-transfected human embryonic kidney cells and developing...
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Over-expression of EphrinA2 in the Anterior Region of the Developing Mouse Midbrain and Diencephalon

Kim J, Park S

  • KMID: 2224468
  • Korean J Anat.
  • 2006 Jun;39(3):177-186.
The Eph family is thought to exert its function through the complementary expression of receptors and ligands. The dorsal mesencephalon appears to be segmented into two broad regions demarcated by the...
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Erythropoietin-producing Human Hepatocellular Carcinoma Receptor B1 Polymorphisms are Associated with HBV-infected Chronic Liver Disease and Hepatocellular Carcinoma in a Korean Population

Kim KY, Lee SK, Kim MH, Cheong JY, Cho SW, Yang KS, Kwack K

  • KMID: 2166419
  • Genomics Inform.
  • 2008 Dec;6(4):192-201.
Erythropoietin-producing human hepatocellular carcinoma receptor B1 (EPHB1) is a member of the Eph family of receptor tyrosine kinases that mediate vascular system development. Eph receptor overexpression has been observed in...
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An integrated review on new targets in the treatment of neuropathic pain

Khangura R, Sharma J, Bali A, Singh N, Jaggi AS

Neuropathic pain is a complex chronic pain state caused by the dysfunction of somatosensory nervous system, and it affects the millions of people worldwide. At present, there are very few...
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EphA2 Receptor Signaling Mediates Inflammatory Responses in Lipopolysaccharide-Induced Lung Injury

Hong JY, Shin MH, Chung KS, Kim EY, Jung JY, Kang YA, Kim YS, Kim SK, Chang J, Park MS

BACKGROUND: Eph receptors and ephrin ligands have several functions including angiogenesis, cell migration, axon guidance, fluid homeostasis, oncogenesis, inflammation and injury repair. The EphA2 receptor potentially mediates the regulation of...
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