- Estrogen modulates transactivations of SXR-mediated liver X receptor response element and CAR-mediated phenobarbital response element in HepG2 cells
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Min G
- KMID: 994396
- Exp Mol Med.
- 2010 Nov;42(11):731-738.
- doi: 10.3858/emm.2010.42.11.074
The nuclear receptors, steroid and xenobiotic receptor (SXR) and constitutive androstane receptor (CAR) play important functions in mediating lipid and drug metabolism in the liver. The present study demonstrates modulatory... -
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- Cross talk between P2 purinergic receptors modulates extracellular ATP-mediated interleukin-10 production in rat microglial cells
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Seo DR, Kim SY, Kim KY, Lee HG, Moon JH, Lee JS, Lee SH, Kim SU, Lee YB
- KMID: 1103584
- Exp Mol Med.
- 2008 Feb;40(1):19-26.
- doi: 10.3858/emm.2008.40.1.19
Previously we demonstrated that ATP released from LPS-activated microglia induced IL-10 expression in a process involving P2 receptors, in an autocrine fashion. Therefore, in the present study we sought to... -
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- The adaptor protein LAD/TSAd mediates laminin-dependent T cell migration via association with the 67 kDa laminin binding protein
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Park E, Choi Y, Ahn E, Park I, Yun Y
- KMID: 1009394
- Exp Mol Med.
- 2009 Oct;41(10):728-736.
- doi: 10.3858/emm.2009.41.10.079
The adaptor protein, LAD/TSAd, plays essential roles in T cell activation. To further understand the functions of this protein, we performed yeast two-hybrid screening using TSAd as bait and identified... -
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- Toll-like receptor signal transduction
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Krishnan J, Selvarajoo K, Tsuchiya M, Lee G, Choi S
- KMID: 756065
- Exp Mol Med.
- 2007 Aug;39(4):421-438.
Toll-like receptors (TLRs) are the archetypal pattern recognition receptors in sensing exogenous pathogens. Activation of TLRs is a first line of defense of the immune system, leading to the activation... -
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- Modifiers of TGF-beta1 effector function as novel therapeutic targets of pulmonary fibrosis
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Lee CM, Park JW, Cho WK, Zhou Y, Han B, Yoon PO, Chae J, Elias JA, Lee CG
- KMID: 1792051
- Korean J Intern Med.
- 2014 May;29(3):281-290.
- doi: 10.3904/kjim.2014.29.3.281
Pulmonary fibrosis is a fatal progressive disease with no effective therapy. Transforming growth factor (TGF)-beta1 has long been regarded as a central mediator of tissue fibrosis that involves multiple organs... -
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