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One target, different effects: a comparison of distinct therapeutic antibodies against the same targets

Shim H

To date, more than 30 antibodies have been approved worldwide for therapeutic use. While the monoclonal antibody market is rapidly growing, the clinical use of therapeutic antibodies is mostly limited...
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Expression of c-erbB-2 and c-met Proteins in Gastric Adenoma and Adenocarcinoma

Lee SW, Kang SB, Kim YS, Nam SW, Lee DS, Lee HK, Han SW

  • KMID: 782837
  • Korean J Gastroenterol.
  • 2007 Mar;49(3):152-157.
BACKGROUND/AIMS: The aim of this study was to investigate the immunohistochemical overexpression of c-erbB-2 and c-met proteins according to the histopathological parameters such as grade of dysplasia, histological type, depth...
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Trastuzumab-Conjugated Liposome-Coated Fluorescent Magnetic Nanoparticles to Target Breast Cancer

Jang M, Yoon YI, Kwon YS, Yoon TJ, Lee HJ, Hwang SI, Yun BL, Kim SM

OBJECTIVE: To synthesize mesoporous silica-core-shell magnetic nanoparticles (MNPs) encapsulated by liposomes (Lipo [MNP@m-SiO2]) in order to enhance their stability, allow them to be used in any buffer solution, and to...
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