- Expressions and Clinical Significances of Angiopoietin-1, Angiopoietin-2, and Tie-2 Receptor in Patients With Colorectal Cancer
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Hong S, Jung HI, Ahn TS, Kim HJ, Lee KT, Baek MJ, Bae SB
- KMID: 2377384
- Ann Coloproctol.
- 2017 Feb;33(1):9-15.
- doi: 10.3393/ac.2017.33.1.9
PURPOSE: Angiopoietin-1 (Ang-1) plays a crucial role in vascular and hematopoietic development, mainly through its cognate receptor, Tie-2. Increased levels of Ang-2 have been shown to be correlated with abnormal... -
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- Angiopoietins in Diabetic Nephropathy
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Lee EY, Gil HW, Yang JO, Koh JH, Chung CH, Hong SY
- KMID: 2079686
- Korean J Nephrol.
- 2007 May;26(3):311-319.
PURPOSE: It has been reported that angiopoietins and Tie-2 receptor play an important role in the maintenance of glomerular filtration barrier in various glomerulonephritis models. We studied the role of... -
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- Tie2 is tied at the cell-cell contacts and to extracellular matrix by Angiopoietin-1
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Fukuhara S, Sako K, Noda K, Nagao K, Miura K, Mochizuki
- KMID: 1123460
- Exp Mol Med.
- 2009 Mar;41(3):133-139.
- doi: 10.3858/emm.2009.41.3.016
Angiopoietin-1 (Ang1) binds to and activates Tie2 receptor tyrosine kinase. Ang1-Tie2 signal has been proposed to exhibit two opposite roles in the controlling blood vessels. One is vascular stabilization and... -
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- The Study on the Expression of Angiopoietin-1, Angiopoietin-2, and Tie2 in Mouse Kidney Maturation
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Kim W, Lee S, Sung MJ, Moon SO, Kim SK, Jang YB, Kim SS, Kang SK, Park SK
- KMID: 2079395
- Korean J Nephrol.
- 2004 May;23(3):385-395.
BACKGROUND: The Angiopoietin-1 (Ang1), Angiopoietin-2 (Ang2) and Tie2 have essential role in angiogenesis in development. Ang1 and Ang2 are ligands which binds to their receptor, Tie2. METHODS: Expression of these... -
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- Expression of Angiopoietin 1, 2 and Their Common Receptor Tie2 in Human Gastric Carcinoma: Implication for Angiogenesis
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Moon WS, Park HS, Yu KH, Jang KY, Kang MJ, Park H, Tarnawski
- KMID: 1781834
- J Korean Med Sci.
- 2006 Apr;21(2):272-278.
- doi: 10.3346/jkms.2006.21.2.272
Angiogenesis, formation of new microvessels providing oxygen and nutrient supply, is essential for tumor growth. It is dependent on the production of angiogenic growth factors by tumor cells. Angiopoietin 1... -
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- CTHRC1 promotes angiogenesis by recruiting Tie2-expressing monocytes to pancreatic tumors
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Lee J, Song J, Kwon ES, Jo S, Kang MK, Kim YJ, Hwang Y, Bae H, Kang TH, Chang S, Cho HJ, Kim SC, Kim S, Koh SS
- KMID: 2361548
- Exp Mol Med.
- 2016 Sep;48(9):e261.
- doi: 10.1038/emm.2016.87
CTHRC1 (collagen triple-helix repeat-containing 1), a protein secreted during the tissue-repair process, is highly expressed in several malignant tumors, including pancreatic cancer. We recently showed that CTHRC1 has an important... -
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