- Structure and Function of a Minimal Receptor Activation Domain of Parathyroid Hormone
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Lee EJ, Kim HY, Cho MK, Lee W, Lim SK
- KMID: 1734123
- Yonsei Med J.
- 2004 Jun;45(3):419-427.
- doi: 10.3349/ymj.2004.45.3.419
The structure and function of short-length amino terminal PTH analogues were studied. The substitution of Leu7 with Phe in [Ala3, 10Leu7Arg11]rPTH (1-11) NH2 analogue peptides did not show any reduction... -
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- Cellular zinc deficiency inhibits the mineralized nodule formation and downregulates bone-specific gene expression in osteoblastic MC3T3-E1 cells
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Cho YE, Kwun IS
- KMID: 2427761
- J Nutr Health.
- 2018 Oct;51(5):379-385.
- doi: 10.4163/jnh.2018.51.5.379
PURPOSE: Zinc (Zn) is an essential trace element for bone mineralization and osteoblast function. We examined the effects of Zn deficiency on osteoblast differentiation and mineralization in MC3T3-E1 cells. METHODS: Osteoblastic... -
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- The N- and C-terminal domains of parathyroid hormone-related protein affect differently the osteogenic and adipogenic potential of human mesenchymal stem cells
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Casado-Diaz A, Santiago-Mora R, Quesada JM
- KMID: 983981
- Exp Mol Med.
- 2010 Feb;42(2):87-98.
- doi: 10.3858/emm.2010.42.2.010
Parathyroid hormone-related protein (PTHrP) is synthesized by diverse tissues, and its processing produces several fragments, each with apparently distinct autocrine and paracrine bioactivities. In bone, PTHrP appears to modulate bone... -
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