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Nerve Growth Factor Stimulates Glioblastoma Proliferation through Notch1 Receptor Signaling

Park JC, Chang IB, Ahn JH, Kim JH, Song JH, Moon SM, Park YH

OBJECTIVE: Notch receptors are heterodimeric transmembrane proteins that regulate cell fate, such as differentiation, proliferation, and apoptosis. Dysregulated Notch pathway signaling has been observed in glioblastomas, as well as in...
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Notch1 in Tumor Microvascular Endothelial Cells and Tumoral miR-34a as Prognostic Markers in Locally Advanced Triple-Negative Breast Cancer

Kim D, Lee J, Kang J, Kim SH, Yoo TK, Oh S, Lee A

PURPOSE: Triple-negative breast cancer (TNBC) is associated with poor prognosis with limited treatment options. Angiogenesis is known to be involved in the progression of TNBC, and targeting this pathway results...
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Co-expression patterns of Notch1, Snail, and p53 in grade III hepatocellular carcinoma with postoperative recurrence: a preliminary study

Jang SK, Choi GH, Choi J, Quan X, Jang JW, Kim BH, Jung G, Park YM

BACKGROUND/AIMS: We aimed to determine the association between the co-expression patterns of Notch1, Snail, and p53 proteins (NSP) and the postoperative prognosis of hepatocellular carcinoma (HCC). METHODS: The immunoblot data for...
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