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Our previous studies document the expression of adrenoceptors and purinoceptors in the rat prostate neuroendocrine cells (RPNECs). However, a direct investigation of the receptors for acetylcholine (ACh) is still lacking...
PURPOSE: The location of acetylcholinesterase-containing nerve fibers suggests a role for acetylcholine in both contractility and secretion in the prostate gland. The colocalization of nitrergic nerves with cholinergic nerves, and...
BACKGROUND: Non-depolarizing muscle relaxants have their muscle relaxing effect by competing with acetylcholine (ACh) at the nicotinic receptor level. What are the effects of such muscle relaxants on the tracheal...
Contraction of smooth muscle is initiated by an increase in
cytosolic Ca2+ leading to activation of Ca2+/calmodulin-dependnet myosin
light chain (MLC) kinase and phosphorylation of MLC. The types of
contraction and signaling mechanisms...