- Epidermal Growth Factor Receptor Is Related to Poor Survival in Glioblastomas: Single-Institution Experience
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Choi Y, Song YJ, Lee HS, Hur WJ, Sung KH, Kim KU, Choi SS, Kim SJ, Kim DC
- KMID: 1776924
- Yonsei Med J.
- 2013 Jan;54(1):101-107.
- doi: 10.3349/ymj.2013.54.1.101
PURPOSE: There are conflicting results surrounding the prognostic significance of epidermal growth factor receptor (EGFR) status in glioblastoma (GBM) patients. Accordingly, we attempted to assess the influence of EGFR expression... -
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- The pleckstrin homology domain of phospholipase D1 accelerates EGFR endocytosis by increasing the expression of the Rab5 effector, rabaptin-5
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Park MH, Choi KY, Min DS
- KMID: 2359887
- Exp Mol Med.
- 2015 Dec;47(12):e200.
- doi: 10.1038/emm.2015.101
Endocytosis is differentially regulated by hypoxia-inducible factor-1alpha (HIF-1alpha) and phospholipase D (PLD). However, the relationship between HIF-1alpha and PLD in endocytosis is unknown. HIF-1alpha is degraded through the prolyl hydroxylase... -
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- Relationship between Preoperative 18F-Fluorodeoxyglucose Uptake and Epidermal Growth Factor Receptor Status in Primary Colorectal Cancer
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Choi YJ, Kim MJ, Lee BH, Kwon MJ, Hwang HS
- KMID: 2466375
- Yonsei Med J.
- 2016 Jan;57(1):232-237.
- doi: 10.3349/ymj.2016.57.1.232
PURPOSE: Both 18F-fluorodeoxyglucose (18F-FDG) uptake and epidermal growth factor receptor (EGFR) status are prognostic variables of colorectal cancer (CRC). The aim of this study was to investigate a possible association... -
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- Evaluation of HER2/neu Status by Real-Time Quantitative PCR in Breast Cancer
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Kim YR, Choi JR, Song KS, Chong WH, Lee HD
- KMID: 1105103
- Yonsei Med J.
- 2002 Jun;43(3):335-340.
- doi: 10.3349/ymj.2002.43.3.335
Over-expression of the human epidermal growth factor receptor-2 (HER2/neu) has been observed in many cancers, and is associated with a poor prognosis. Recent adjuvant treatment with anti-HER2 monoclonal antibodies in... -
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- Neutrophil Elastase Causes MUC5AC Mucin Synthesis Via EGF Receptor, ERK and NF-kB Pathways in A549 Cells
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Song JS, Cho KS, Yoon HK, Moon HS, Park SH
- KMID: 1115250
- Korean J Intern Med.
- 2005 Dec;20(4):275-283.
- doi: 10.3904/kjim.2005.20.4.275
BACKGROUND: Neutrophil elastase (NE) was found to increase the respiratory mucin gene, MUC5AC, although the molecular mechanisms of this process remain unknown. We attempted to determine the signal transduction pathway... -
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- Imaging Characteristics of Stage I Non-Small Cell Lung Cancer on CT and FDG-PET: Relationship with Epidermal Growth Factor Receptor Protein Expression Status and Survival
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Lee Y, Lee HJ, Kim YT, Kang CH, Goo JM, Park CM, Paeng JC, Chung DH, Jeon YK
- KMID: 1482802
- Korean J Radiol.
- 2013 Apr;14(2):375-383.
- doi: 10.3348/kjr.2013.14.2.375
OBJECTIVE: To identify CT and FDG-PET features associated with epidermal growth factor receptor (EGFR) protein overexpression, and to evaluate whether imaging features and EGFR-overexpression can help predict clinical outcome. MATERIALS AND... -
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- Expression of ErbB Receptor Proteins and TGF-alpha during Diethylnitrosamine-induced Hepatocarcinogenesis in the Rat Liver
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Lee TY, Kim KT, Han SY
- KMID: 760707
- Korean J Hepatol.
- 2007 Mar;13(1):70-80.
BACKGROUND/AIMS: ErbB receptor proteins are transmembrane tyrosine kinase receptors; when they are activated by interaction with ligands, they generate diverse cellular responses, especially during lesion development and progression to... -
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