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Molecular Analysis of Protease and Reverse Transcriptase in an AIDS Patient with HAART - Failure

Cho YK, Lee HJ, Lee HR, Kim YK

  • KMID: 1621379
  • J Bacteriol Virol.
  • 2001 Mar;31(1):63-68.
No abstract available.
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Detection of Circulating Cancer Cells in Prostate Cancer Patients using Reverse Transcriptase Polymerase Chin Reaction for prostate Specific Membrane Antigen mRNA

Park YI, Choi DJ, Kwon DD, Oh BR, Lim WH, Suh SP, Ryu SB

  • KMID: 1582989
  • Korean J Urol.
  • 2000 Apr;41(4):480-485.
No abstract available.
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Compiling Multicopy Single-Stranded DNA Sequences from Bacterial Genome Sequences

Yoo W, Lim D, Kim S

A retron is a bacterial retroelement that encodes an RNA gene and a reverse transcriptase (RT). The former, once transcribed, works as a template primer for reverse transcription by the...
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Telomerase Activity and Expression of Telomerase RNA in Malignant Fibrous Histiocytoma

Yoo J, Kang SJ, Kim BK

  • KMID: 2011743
  • Korean J Pathol.
  • 2000 Aug;34(8):581-587.
Telomerase is an RNA-dependent DNA polymerase that synthesizes TTAGGG telomeric DNA onto chromosomal ends to compensate for sequence loss during replication. It has been detected in a variety of human...
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Detection of Mutations to Zidovudine in the pol Gene of Human Immunodeficiency Virus-1 by Direct Sequencing

Cho YK, Lee HJ, Sung HS, Kim YK, Kim YB, Lee Y, Kim MJ, Kim DG, Won YH, Cho GJ

  • KMID: 1544233
  • J Korean Soc Virol.
  • 1999 Dec;29(4):271-281.
No abstract available.
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The clinical significance of Interleukin-6 mRNA expression in cervical intraepithelial neoplasia and cervical cancer

Moon HS, Choi EA, Chung HW

  • KMID: 2262717
  • Korean J Obstet Gynecol.
  • 2002 Apr;45(4):659-665.
OBJECTIVES: Interleukin-6 is a pleiotrophic cytokine that is not only a mediator in major immunologic reactions but also a growth factor of keratinocytes. We studied IL-6 mRNA expression in cervical...
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The Midkine mRNA Expression in Invasive Cervical Cancer

Moon HS, Park HM, Chung HW

  • KMID: 1928705
  • Korean J Gynecol Oncol Colposc.
  • 2000 Jun;11(2):123-130.
OBJECTIVE: Some growth factors may promote tumor growth by affecting tumor angiogenesis. Midkine(MK) are polypeptides that belong to a new family of heparin-binding growth/differentiation factor and has also been...
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Telomerase Activity and Expression of hTR and TERT in Human Soft Tissue Sarcomas

Yoo J, Kang SJ, Kim BK

  • KMID: 1972968
  • Cancer Res Treat.
  • 2002 Feb;34(1):46-51.
PURPOSE: Sarcomas have rarely been analyzed for telomerase, which is an RNA-dependent DNA polymerase to maintain telomeres and prevent telomere shortening. This study was undertaken to determine telomerase activity and...
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Application of CRISPR/Cas9 in Treating Hepatitis B Virus

Cho JY

The advent of oral antiviral agents has revolutionized hepatitis B treatment. It has led to decreased incidence and mortality related to hepatocellular carcinoma. However, although nucleos(t)ide analogs (NA) are fast...
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Telomerase Activity in Gastric Adenocarcinomas: Frozen Tissues Versus Methacarn-fixed Paraffin-embedded Tissues

Yoo J, Kang SJ, Kang CS

  • KMID: 1972867
  • Cancer Res Treat.
  • 2003 Dec;35(6):478-482.
PURPOSE: Telomerase is an RNA-dependent DNA polymerase that synthesizes TTAGGG telomeric DNA onto chromosome ends to compensate for sequence loss during DNA replication. It has been detected in 85~90% of...
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The Expression of MT1-MMP and E-cadherin mRNA in Invasive Cervical Cancer

Moon HS, Choi EA, Chung HW, Kim SC

  • KMID: 2244942
  • Korean J Gynecol Oncol Colposc.
  • 2002 Jun;13(2):106-115.
OBJECTIVES: There are adhesion molecules, angiogenetic factors, and proteolytic enzymes such as E-cadherin and MT1-MMP, which are involved in carcinogenesis, cancer invasion and metastasis. The aim of this study was...
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Detection of Major bcr/abl mRNA from Stored Bone Marrow Aspirate Smears Using the Reverse Transcriptase Polymerase Chain Reaction

Lee EY, Shin JH, Jun ES

  • KMID: 2089457
  • Korean J Clin Pathol.
  • 1997 Aug;17(4):668-675.
BACKGROUND: The verse transcriptase polymerase chain reaction (RT-PCR) has been widely used to analyze the bcr/abl fusion mRNA in chronic myelogenous leukemia (CML). Fresh or cryopreserved cells may not always...
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Expression of telomerase RNA and caspase-3 in cervical intraepithelial lesions and invasive carcinoma

Kim YO, Lee CJ

  • KMID: 2244564
  • Korean J Gynecol Oncol.
  • 2007 Jun;18(2):131-138.
OBJECTIVE: Telomerase is an RNA-dependent DNA polymerase that synthesizes TTAGGG telomeric DNA. It has been detected in a variety of human malignancies, suggesting that it's activity may play a role...
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Molecular Characterization of the L Segment of Hantann Virus, Strain Howang

Chu YK, Song DY, Koo HM, Lee HW

  • KMID: 1544247
  • J Korean Soc Virol.
  • 1999 Sep;29(3):155-163.
Hantaan virus (HTNV), the etiologic agent of hemorrhagic fever with renal syndrome (HFRS), belongs to the genus Hantavirus, and has three single negative straded RNA genome segments. HTNV strain Howang...
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Prevalence of Zidovudine Resistant Human Immunodeficiency Virus Type 1 in Zidovudine-naive Patients

Kim NJ, Choi ES, Kim ES, Lee DH, Choe YJ, Bang JH, Oh MD, Choe KW

  • KMID: 1599898
  • Korean J Infect Dis.
  • 2001 Feb;33(1):40-45.
BACKGROUD: Drug resistant virus has been seen with all effective antiretroviral drugs in current practice. The isolation of resistant virus from subjects is associated with more rapid clinical outcome. The...
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Telomerase Activity in Various Benign, Premalignant and Malignant Skin Tumors

Cha JH, Oh CK, Jang HS, Kwon KS

  • KMID: 2146463
  • Korean J Dermatol.
  • 2000 Dec;38(12):1590-1597.
BACKGROUND: Telomerase is a ribonucleoprotein complex with RNA-dependent DNA polymerase which is necessary in maintenance of the length of chromosome, and therefore, in preventing genomic instability. Its activity is regarded...
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Detection of resistance mutation to lamivudine in HIV-1 infected patients

Cho YK, Sung HS, Lee HJ, Kim YK, Chi HS, Cho GJ, Kang MW

  • KMID: 2146891
  • J Korean Soc Microbiol.
  • 2000 Apr;35(2):181-190.
To investigate resistance to lamivudine (3TC), we examined the incidence of M184V in 20 HIV-1 patients treated with 3TC for 13.1 +/- 9 months. Fourteen of 20 patients had been exposed to...
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Effects of Connexin Expression on Detrusor Overactivity in Male Patients with Bladder Outlet Obstruction Caused by Benign Prostatic Hyperplasia

Cha SH, Kim JC, Hwang TK

  • KMID: 2293526
  • Korean J Urol.
  • 2004 Sep;45(9):897-902.
PURPOSE: Detrusor overactivity is frequently associated with bladder outlet obstruction, which may be related with increased electrical coupling. The effects of connexin 43(Cx43) and connexin 26(Cx26) mRNA expressions on the...
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Telomerase Activity in Oral Leukoplakia Tissues

Tae K, Ahn MJ, Lee HS, Park BJ, Ahn KS

  • KMID: 2074334
  • Korean J Otolaryngol-Head Neck Surg.
  • 1999 Jan;42(1):82-87.
BACKGROUND AND OBJECTIVES: Telomeres are specialized structures found at the ends of eukaryotic chromosomes. Telomeres stabilize the chromosome and protect DNA from illegitimate recombination. Telomerase is a ribonucleoprotein, a RNA...
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Telomerase Activity in Breast Cancer and Benign Breast Disease of Korea

Park WC, Seo YJ, Choi SH, You YK, Cho WI, Kim CS, Oh SC, Jung SS, Kim IC

BACKGROUND: Telomerase is an RNA-dependent DNA polymerase that compensates for the telomere shortening that occurs in its absence. Reactivation of telomerase is thought to be an important step in cellular...
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