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Optimization of Protein Extraction for Lichen Thalli

Kondratiuk AS, Savchuk OM, Hur JS

Lichen-forming fungal proteins have been seldom searched due to many difficulties in their extraction. Phenols, quinones, proteases, and other components released during cell disruption have been known to be the...
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A Case of Chemical Burn by Pheropsophus Jessoensis

Choi MJ, Park HJ, Lee JY, Cho BK, Lee IY

  • KMID: 2038685
  • Korean J Dermatol.
  • 2002 Dec;40(12):1531-1533.
Pheropsophus jessoensis, bombardier beetle, when physically assaulted, produces diverse toxicants, often at high concentrations, including acids, aldehydes, phenols, and quinones. They can eject these fluids forcibly, in the form of...
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Immunomodulatory Effects of Hypocrellin A on MHC-restricted Antigen Processing

Park S, Im SA, Kim KH, Lee CK

Hypocrellin A has gained much attention in recent years due to its light-induced antitumor, antifungal and antiviral activities. Here we report that hypocrellin A exerts immunomodulatory effects on MHC-restricted presentation...
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Increased Cellular NAD⁺ Level through NQO1 Enzymatic Action Has Protective Effects on Bleomycin-Induced Lung Fibrosis in Mice

Oh GS, Lee SB, Karna A, Kim HJ, Shen A, Pandit A, Lee S, Yang SH, So HS

BACKGROUND: Idiopathic pulmonary fibrosis is a common interstitial lung disease; it is a chronic, progressive, and fatal lung disease of unknown etiology. Over the last two decades, knowledge about the...
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The Effects of Mesima-Ex, the Immunomodulator in Curatively Resected Gastric Cancer

Cho SH, Kim JH, Park BK, Park SJ, Ahn SH, Jung HC, Rho JK, Kim BS, Rho SH

  • KMID: 2059147
  • J Korean Cancer Assoc.
  • 1997 Oct;29(5):800-806.
PURPOSE: The Mesima-Ex is a kind of biologic response modifier, which is extracted from a mushroom called Phellinus linteus. Mesima-Ex consists of various chemical compounds which include protein bound polysaccharide,...
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Ajoene, a Major Organosulfide Found in Crushed Garlic, Induces NAD(P)H:quinone Oxidoreductase Expression Through Nuclear Factor E2-related Factor-2 Activation in Human Breast Epithelial Cells

Cho SJ, Ryu JH, Surh YJ

BACKGROUND: NAD(P)H:quinone oxidoreductase-1 (NQO1) is a widely-distributed flavin adenine dinucleotide-dependent flavoprotein that promotes obligatory 2-electron reductions of quinones, quinoneimines, nitroaromatics, and azo dyes. This reduces quinone levels and thereby minimizes...
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Involvement of throm box aneA2 and tyrosine kinase in the synergistic interaction of platelet activating factor and calcium ionophore A23187 in human platelet aggregation

Rasheed H, Saeed SA

  • KMID: 1097103
  • Exp Mol Med.
  • 2004 Jun;36(3):220-225.
The present study was carried out to examine the mechanisms of the synergistic interaction of PAF and A23187 mediated platelet aggregation. We found that platelet aggregation mediated by subthreshold concentrations...
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Role of Ras/ERK-dependent pathway in the erythroid differentiation of K562 cells

Kang CD, Do IR, Kim KW, Ahn BK, Kim SH, Chung BS, Jhun BH, Yoo MA

  • KMID: 1029935
  • Exp Mol Med.
  • 1999 Jun;31(2):76-82.
The chronic myelogenous leukemic K562 cell line carrying Bcr-Abl tyrosine kinase is considered as pluripotent hematopoietic progenitor cells expressing markers for erythroid, granulocytic, monocytic, and megakaryocytic lineages. Here we investigated the signaling modulations...
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