- Transformation into large-cell neuroendocrine carcinoma associated with acquired resistance to erlotinib in nonsmall cell lung cancer
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Lim JU, Woo IS, Jung YH, Byeon JH, Park CK, Kim TJ, Kim HR
- KMID: 2070144
- Korean J Intern Med.
- 2014 Nov;29(6):830-833.
- doi: 10.3904/kjim.2014.29.6.830
No abstract available. -
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- Post-Progression Survival in Patients with Non-Small Cell Lung Cancer with Clinically Acquired Resistance to Gefitinib
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Kim H, Yun T, Lee YJ, Han JY, Kim HT, Lee GK
- KMID: 1777655
- J Korean Med Sci.
- 2013 Nov;28(11):1595-1602.
- doi: 10.3346/jkms.2013.28.11.1595
Most patients with tyrosine kinase inhibitor (TKI)-sensitive non-small cell lung cancer (NSCLC) eventually develop acquired resistance to TKIs. Factors that affect TKI-sensitive patient survival after progression during TKI treatment remain... -
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- Clinical efficacy of erlotinib, a salvage treatment for non-small cell lung cancer patients following gefitinib failure
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Cho KM, Keam B, Kim TM, Lee SH, Kim DW, Heo DS
- KMID: 2381594
- Korean J Intern Med.
- 2015 Nov;30(6):891-898.
- doi: 10.3904/kjim.2015.30.6.891
BACKGROUND/AIMS: The purpose of this study was to identify predictive factors for erlotinib treatment in non-small cell lung cancer (NSCLC) patients following gefitinib failure. METHODS: Forty-five patients with NSCLC who were... -
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- An important role for peroxiredoxin II in survival of A549 lung cancer cells resistant to gefitinib
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Kwon T, Rho JK, Lee JC, Park YH, Shin HJ, Cho S, Kang YK, Kim BY, Yoon DY, Yu DY
- KMID: 2155657
- Exp Mol Med.
- 2015 May;47(5):e165.
- doi: 10.1038/emm.2015.24
Redox adaptation is an important concept that explains the mechanisms by which cancer cells survive under persistent endogenous oxidative stress and become resistant to certain anticancer agents. To investigate this... -
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- Potential use of an anticancer drug gefinitib, an EGFR inhibitor, on allergic airway inflammation
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Hur GY, Lee SY, Lee SH, Kim SJ, Lee KJ, Jung JY, Lee EJ, Kang EH, Jung KH, Lee SY, Kim JH, Shin C, Shim JJ, In KH, Kang KH, Yoo SH
- KMID: 1047088
- Exp Mol Med.
- 2007 Jun;39(3):367-375.
The EGFR plays an essential role in goblet cell hyperplasia and mucus hypersecretion. EGFR has an intrinsic tyrosine kinase activity that, when activated, induces the production of MUC5AC through the... -
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