- Microflora Modulation of Motility
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Quigley EM
- KMID: 2326207
- J Neurogastroenterol Motil.
- 2011 Apr;17(2):140-147.
That gastrointestinal motility can influence the gut microbiota has been known for decades and the clinical consequences of impaired motility, in terms of the bacterial population of the small intestine,... -
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- Prokinetics in the Management of Functional Gastrointestinal Disorders
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Quigley EM
- KMID: 2433472
- J Neurogastroenterol Motil.
- 2015 Jul;21(3):330-336.
- doi: 10.5056/jnm15094
A variety of common and some not common gastrointestinal syndromes are thought to be based on impaired gut motility. For some, the role of motility is well defined, for others... -
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- Pharmabiotic Manipulation of the Microbiota in Gastrointestinal Disorders: A Clinical Perspective
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Giron F, Quigley EM
- KMID: 2417380
- J Neurogastroenterol Motil.
- 2018 Jul;24(3):355-366.
- doi: 10.5056/jnm18004
The advent and widespread availability of high-throughput technology has revolutionized the assessment of the communities of microorganisms that inhabit the gastrointestinal tract––the gut microbiota. As our understanding of the role... -
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- Computed Tomography Assessment of Intestinal Gas Volumes in Functional Gastrointestinal Disorders
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Mc Williams SR, Mc Laughlin PD, O'Connor O, Desmond AN, Ni Laoire , Shanahan F, Quigley EM, Maher MM
- KMID: 2325952
- J Neurogastroenterol Motil.
- 2012 Oct;18(4):419-425.
BACKGROUND/AIMS: Many patients with functional gastrointestinal disorders (FGIDs) rank sensations of bloating and distension among their most debilitating symptoms. Previous studies that have examined intestinal gas volume (IGV) in patients... -
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- Effect of Prucalopride in the Treatment of Chronic Constipation in Asian and Non-Asian Women: A Pooled Analysis of 4 Randomized, Placebo-controlled Studies
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Ke M, Tack J, Quigley EM, Zou D, Choi SC, Leelakusolvong S, Liu A, Kim J
- KMID: 2381209
- J Neurogastroenterol Motil.
- 2014 Oct;20(4):458-468.
- doi: 10.5056/jnm14029
BACKGROUND/AIMS: To compare the efficacy and safety of prucalopride, a novel selective high-affinity 5-hydroxytryptamine type 4 receptor agonist, versus placebo, in Asian and non-Asian women with chronic constipation (CC). METHODS: Data... -
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- Factors Predictive of Treatment-Emergent Adverse Events of Prucalopride: An Integrated Analysis of Four Randomized, Double-Blind, Placebo-Controlled Trials
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Leelakusolvong S, Ke M, Zou D, Choi SC, Tack J, Quigley EM, Liu A, Kim J
- KMID: 2380766
- Gut Liver.
- 2015 Mar;9(2):208-213.
- doi: 10.5009/gnl14290
BACKGROUND/AIMS: This integrated analysis aimed to identify the factors associated with the most frequently reported treatment-emergent adverse events (TEAEs) in Asian and non-Asian patients with chronic constipation (CC) who receive... -
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