- Recent progress in vaccine development targeting pre-clinical human toxoplasmosis
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Chu KB, Quan FS
- KMID: 2545449
- Parasit Host Dis.
- 2023 Aug;61(3):231-239.
- doi: 10.3347/PHD.22097
Toxoplasma gondii is an intracellular parasitic organism affecting all warm-blooded vertebrates. Due to the unavailability of commercialized human T. gondii vaccine, many studies have been reported investigating the protective efficacy... -
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- The infection status of anisakid larvae in marine fish and cephalopods from the Bohai Sea, China and their taxonomical consideration
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Ma HW, Jiang TJ, Quan FS, Chen XG, Wang HD, Zhang YS, Cui MS, Zhi WY, Jiang DC
- KMID: 1715332
- Korean J Parasitol.
- 1997 Mar;35(1):19-24.
- doi: 10.3347/kjp.1997.35.1.19
The infection status of anisakid larvae was examined in 290 marine fish of 25 species and in 108 cephalopods of 3 species purchased in Bayuquan region, Yingko city nearby the... -
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- Effect of 2, 6-Dichlorobenzonitrile on Amoebicidal Activity of Multipurpose Contact Lens Disinfecting Solutions
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Moon EK, Lee S, Quan FS, Kong HH
- KMID: 2426754
- Korean J Parasitol.
- 2018 Oct;56(5):491-494.
- doi: 10.3347/kjp.2018.56.5.491
Multipurpose contact lens disinfecting solutions (MPDS) are widely used to cleanse and disinfect microorganisms. However, disinfection efficacy of these MPDS against Acanthamoeba cyst remain insufficient. 2, 6-dichlorobenzonitrile (DCB), a cellulose... -
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- Phagocytosis-associated genes in Acanthamoeba castellanii feeding on Escherichia coli
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Kim MJ, Moon EK, Jo HJ, Quan FS, Kong HH
- KMID: 2548516
- Parasit Host Dis.
- 2023 Nov;61(4):397-404.
- doi: 10.3347/PHD.23088
Acanthamoeba species are free-living amoebae those are widely distributed in the environment. They feed on various microorganisms, including bacteria, fungi, and algae. Although majority of the microbes phagocytosed by Acanthamoeba... -
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- Efficacy of Korean Multipurpose Contact Lens Disinfecting Solutions against Acanthamoeba castellanii
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Moon EK, Park HR, Quan FS, Kong HH
- KMID: 2367409
- Korean J Parasitol.
- 2016 Dec;54(6):697-702.
- doi: 10.3347/kjp.2016.54.6.697
Acanthamoeba keratitis has been increasing in recent years. Main risk factors are contact lens wear and their cleaning solutions. Most contact lens wearers use multipurpose disinfecting solutions (MPDS) for cleansing... -
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- Differentially Expressed Gene Profile of Acanthamoeba castellanii Induced by an Endosymbiont Legionella pneumophila
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Moon EK, Park SM, Chu KB, Quan FS, Kong HH
- KMID: 2512988
- Korean J Parasitol.
- 2021 Feb;59(1):67-75.
- doi: 10.3347/kjp.2021.59.1.67
Legionella pneumophila is an opportunistic pathogen that survives and proliferates within protists such as Acanthamoeba spp. in environment. However, intracellular pathogenic endosymbiosis and its implications within Acanthamoeba spp. remain poorly... -
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- Characterization of a Peptide Antibody Specific to the Adenylyl Cyclase-Associated Protein of Acanthamoeba castellanii
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Kim MJ, Lee HA, Quan FS, Kong HH, Moon EK
- KMID: 2526669
- Korean J Parasitol.
- 2022 Feb;60(1):7-14.
- doi: 10.3347/kjp.2022.60.1.7
Acanthamoeba keratitis (AK) is a rare infectious disease and accurate diagnosis has remained arduous as clinical manifestations of AK were similar to keratitis of viral, bacterial, or fungal origins. In... -
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- Detection of Toxoplasma gondii Infections using Virus-Like Particles Displaying T. gondii ROP4 Antigen
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Kim MJ, Mao J, Kang HJ, Chu KB, Quan FS
- KMID: 2523528
- Korean J Parasitol.
- 2021 Dec;59(6):565-572.
- doi: 10.3347/kjp.2021.59.6.565
Toxoplasma gondii ME49 infections are typically diagnosed by serological tests. However, serological diagnosis of RH strain-induced toxoplasmosis remains unknown. In order to develop seradiagnosis of above 2 kinds of infections,... -
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- Identification and Characterization of Protein Arginine Methyltransferase 1 in Acanthamoeba castellanii
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Moon EK, Kong HH, Hong Y, Lee HA, Quan FS
- KMID: 2379411
- Korean J Parasitol.
- 2017 Apr;55(2):109-114.
- doi: 10.3347/kjp.2017.55.2.109
Protein arginine methyltransferase (PRMT) is an important epigenetic regulator in eukaryotic cells. During encystation, an essential process for Acanthamoeba survival, the expression of a lot of genes involved in the... -
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- DNA Methylation of Gene Expression in Acanthamoeba castellanii Encystation
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Moon EK, Hong Y, Lee HA, Quan FS, Kong HH
- KMID: 2379412
- Korean J Parasitol.
- 2017 Apr;55(2):115-120.
- doi: 10.3347/kjp.2017.55.2.115
Encystation mediating cyst specific cysteine proteinase (CSCP) of Acanthamoeba castellanii is expressed remarkably during encystation. However, the molecular mechanism involved in the regulation of CSCP gene expression remains unclear. In... -
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- Influenza M1 Virus-Like Particles Consisting of Toxoplasma gondii Rhoptry Protein 4
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Lee SH, Lee DH, Piao Y, Moon EK, Quan FS
- KMID: 2379416
- Korean J Parasitol.
- 2017 Apr;55(2):143-148.
- doi: 10.3347/kjp.2017.55.2.143
Toxoplasma gondii infections occur throughout the world, and efforts are needed to develop various vaccine candidates expressing recombinant protein antigens. In this study, influenza matrix protein (M1) virus-like particles (VLPs)... -
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- Virus-Like Particles Expressing Toxoplasma gondii Rhoptry Protein 18 Induces Better Protection Than Rhoptry Protein 4 against T. gondii Infection
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Kang HJ, Lee SH, Chu KB, Lee DH, Quan FS
- KMID: 2426747
- Korean J Parasitol.
- 2018 Oct;56(5):429-435.
- doi: 10.3347/kjp.2018.56.5.429
Toxoplasma gondii is a ubiquitous protozoan parasite responsible for causing toxoplasmosis. Preventive measures for toxoplasmosis are currently lacking and as such, development of novel vaccines are of urgent need. In... -
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- Parasite Infiltration and Apoptosis in Spleen upon Toxoplasma gondii Infection
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Lee SH, Chu KB, Quan FS
- KMID: 2463744
- Korean J Parasitol.
- 2019 Oct;57(5):537-541.
- doi: 10.3347/kjp.2019.57.5.537
Toxoplasma gondii infection induces parasite infiltration and apoptosis in the spleen. However, dose-dependent parasite infiltration, apoptosis, body weight alternations and survival in mice remain largely unknown. In this study, mice... -
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- Immune Correlates of Resistance to Trichinella spiralis Reinfection in Mice
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Chu KB, Kim SS, Lee SH, Lee DH, Kim AR, Quan FS
- KMID: 2360528
- Korean J Parasitol.
- 2016 Oct;54(5):637-643.
- doi: 10.3347/kjp.2016.54.5.637
The immune correlate of host resistance induced by reinfection of Trichinella spiralis remains unclear. In this study, we investigated immune correlates between the resistance and serum IgG antibody level, CD23âº... -
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- Previous Infection with Plasmodium berghei Confers Resistance to Toxoplasma gondii Infection in Mice
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Lee DH, Chu KB, Kang HJ, Lee SH, Quan FS
- KMID: 2448140
- Korean J Parasitol.
- 2019 Apr;57(2):93-99.
- doi: 10.3347/kjp.2019.57.2.93
Both Plasmodium spp. and Toxoplasma gondii are important apicomplexan parasites, which infect humans worldwide. Genetic analyses have revealed that 33% of amino acid sequences of inner membrane complex from the... -
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- Comparison of Proteins Secreted into Extracellular Space of Pathogenic and Non-pathogenic Acanthamoeba castellanii
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Moon EK, Choi HS, Park SM, Kong HH, Quan FS
- KMID: 2441615
- Korean J Parasitol.
- 2018 Dec;56(6):553-558.
- doi: 10.3347/kjp.2018.56.6.553
Pathogenic Acanthamoeba spp. cause granulomatous amoebic encephalitis and keratitis. Acanthamoeba keratitis (AK) is a rare but serious ocular infection that can result in permanent visual impairment or blindness. However, pathogenic... -
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- The detection of Toxoplasma gondii ME49 infections in BALB/c mice using various techniques
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Kang HJ, Mao J, Kim MJ, Yoon KW, Eom GD, Chu KB, Moon EK, Quan FS
- KMID: 2548518
- Parasit Host Dis.
- 2023 Nov;61(4):418-427.
- doi: 10.3347/PHD.23048
Toxoplasma gondii infections are primarily diagnosed by serological assays, whereas molecular and fluorescence-based techniques are garnering attention for their high sensitivity in detecting these infections. Nevertheless, each detection method has... -
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- Low Levels of Polymorphisms and Negative Selection in Plasmodum knowlesi Merozoite Surface Protein 8 in Malaysian Isolates
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Ahmed MA, Kang HJ, Quan FS
- KMID: 2459485
- Korean J Parasitol.
- 2019 Aug;57(4):445-450.
- doi: 10.3347/kjp.2019.57.4.445
Human infections due to the monkey malaria parasite Plasmodium knowlesi is increasingly being reported from most Southeast Asian countries specifically Malaysia. The parasite causes severe and fatal malaria thus there... -
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- Specific Detection of Acanthamoeba species using Polyclonal Peptide Antibody Targeting the Periplasmic Binding Protein of A. castellanii
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Kim MJ, Quan FS, Kong HH, Kim JH, Moon EK
- KMID: 2529678
- Korean J Parasitol.
- 2022 Apr;60(2):143-147.
- doi: 10.3347/kjp.2022.60.2.143
Acanthamoeba keratitis (AK) is a rare ocular disease, but it is a painful and sight-threatening infectious disease. Early diagnosis and adequate treatment are necessary to prevent serious complications. While AK... -
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- Virus-like particles expressing microneme-associated antigen of Plasmodium berghei confer better protection than those expressing apical membrane antigen 1
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Kim MJ, Chu KB, Yoon KW, Kang HJ, Lee DH, Moon EK, Quan FS
- KMID: 2556157
- Parasit Host Dis.
- 2024 May;62(2):193-204.
- doi: 10.3347/PHD.24017
Malaria is a global disease affecting a large portion of the world’s population. Although vaccines have recently become available, their efficacies are suboptimal. We generated virus-like particles (VLPs) that expressed... -
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