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Pharmacokinetics/Pharmacodynamics models of veterinary antimicrobial agents

Luo W, Chen D, Wu M, Li Z, Tao Y, Liu Q, Pan Y, Qu W, Yuan Z, Xie S

Misuse and abuse of veterinary antimicrobial agents have led to an alarming increase in bacterial resistance, clinical treatment failure, and drug residues. To address these problems, consistent and appropriate dosage...
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CYP19 gene variant confers susceptibility to endometriosis-associated infertility in Chinese women

Wang L, Lu X, Wang D, Qu W, Li W, Xu X, Huang Q, Han X, Lv J

An aromatase encoded by the CYP19 gene catalyzes the final step in the biosynthesis of estrogens, which is related to endometriosis development. To assess the association of CYP19 gene polymorphisms...
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Formulation of a rational dosage regimen of ceftiofur hydrochloride oily suspension by pharmacokineticpharmacodynamic (PK-PD) model for treatment of swine Streptococcus suis infection

Luo W, Wang D, Qin H, Chen D, Pan Y, Qu W, Huang L, Xie S

Background: Our previously prepared ceftiofur (CEF) hydrochloride oily suspension shows potential wide applications for controlling swine Streptococcus suis infections, while the irrational dose has not been formulated. Objectives: The rational dose...
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