- The Role of the Central Parasympathetic Nervous System in Modulating Glucose Metabolism in Streptozotocin-induced Diabetic Rats
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Lee KE, Pae YS
- KMID: 1964933
- Ewha Med J.
- 1995 Jun;18(2):97-103.
- doi: 10.12771/emj.1995.18.2.97
Insulin controls the levels of blood sugar by inhibiting glucose release from liver and by stimulating glucose utilization in muscle and adipose tissues. In addition to its peripheral effects, insulin... -
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- Influence of Physiological and Environmental Factors on Growth and Sporulation of an Antagonistic Strain of Trichoderma viride RSR 7
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Jayaswal R, Singh R, Lee YS
- KMID: 2052978
- Mycobiology.
- 2003 Mar;31(1):36-41.
- doi: 10.4489/MYCO.2003.31.1.036
Influence of physiological and environmental factors on an antagonistic strain of Trichoderma viride RSR7 were studied optimize its biocontrol potential. The growth and sporulation of T. viride was greatly influenced... -
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- A Familial Case of Leigh Disease
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Kim JH, Kim IJ, Kim IS, Yoon WS, Kim EY, Kim SH, Woo YJ
- KMID: 2329218
- J Korean Child Neurol Soc.
- 1997 Oct;5(1):147-152.
In two female siblings, growth and developmental retardation, poor sucking, anorexia, floppiness and respiratory difficulty developed around 2 and 4 monthes of age in each, and the respiratory symptoms rapidly... -
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- Cytotoxic Effects of Gallic Acid and its Derivatives Against HIV-I-infected Microglia
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Jeong JJ, Lee YS, Kim DH
- KMID: 2366869
- J Bacteriol Virol.
- 2016 Dec;46(4):239-247.
- doi: 10.4167/jbv.2016.46.4.239
In the previous study, we found that flavonoids and ginsenosides exhibited high eliminate rates of human immunodeficiency virus type 1 (HIV-1) D3-transfected macrophages. Based on these findings, here we synthesized... -
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- Inhibition of Sarcoplasmic Reticulum Ca2+ Uptake by Pyruvate and Fatty Acid in H9c2 Cardiomyocytes: Implications for Diabetic Cardiomyopathy
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Lee EH, Lee HK, Kim HW, Kim YH
- KMID: 1600069
- Korean J Physiol Pharmacol.
- 2005 Aug;9(4):195-201.
High extracellular glucose concentration was reported to suppress intracellular Ca2+ clearing through altered sarcoplasmic reticulum (SR) function. In the present study, we attempted to elucidate the effects of pyruvate and... -
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- Purification and characterization of lactate dehydrogenase from Varanus liver
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Javed MH M, Azimuddin , Hussain AN, Ahmed A, Ishaq M
- KMID: 2128622
- Exp Mol Med.
- 1997 Mar;29(1):25-30.
Lactate dehydrogenase was purified 21-fold from liver of Varanus bengalensis using colchicine-sepharose column chromatography. The crude enzyme showed two isoenzymes (LDH-5 and LDH-4) by agarose gel electrophoresis (AGE). The purified... -
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- Multimodality Monitoring in the Neurointensive Care Unit: A Special Perspective for Patients with Stroke
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Ko SB
- KMID: 1824945
- J Stroke.
- 2013 May;15(2):99-108.
- doi: 10.5853/jos.2013.15.2.99
Multimodality monitoring (MMM) is a recently developed method that aids in understanding real-time brain physiology. Early detection of physiological disturbances is possible with the help of MMM, which allows identification... -
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- Activities of Serum Lactate Dehydrohenase and Lactate Dehydrogenase Isoenzymes Activities by Small Opacity Groups on Chest Radiographs in Coal Worker's Pneumoconiosis Patients
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chung HD, Hong JP
- KMID: 2027874
- Korean J Occup Environ Med.
- 1990 Aug;2(2):206-211.
Serum lactate degydrogenase (LD) and LD isoenzyme activities were evaluated in sera from 74 patients of coal workers' pneumoconiosis (CWP) to investigate biochemical changes of these enzyme activities according to... -
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- Anesthetic experience in a pediatric patient with pyruvate dehydrogenase complex (PDHC) deficiency: A case report
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Ro J, Kim EJ, Lee JH, Lee SG, Ban JS, Min BW
- KMID: 2243008
- Korean J Anesthesiol.
- 2008 Nov;55(5):629-633.
- doi: 10.4097/kjae.2008.55.5.629
Mitochondrial dysfunction represents a biochemically and clinically diverse group of conditions that can affect any organs with high energy requirement such as brain and muscle being particularly vulnerable. Pyruvate dehydrogenase... -
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- Epinephrine-induced lactic acidosis in orthognathic surgery: a report of two cases
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Son HW, Park SH, Cho HO, Shin YJ, Son JH
- KMID: 2356257
- J Korean Assoc Oral Maxillofac Surg.
- 2016 Oct;42(5):295-300.
- doi: 10.5125/jkaoms.2016.42.5.295
Submucosal infiltration and the topical application of epinephrine as a vasoconstrictor produce excellent hemostasis during surgery. The hemodynamic effects of epinephrine have been documented in numerous studies. However, its metabolic... -
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- The Role of Pyruvate Dehydrogenase Kinase in Diabetes and Obesity
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Lee IK
- KMID: 2280687
- Diabetes Metab J.
- 2014 Jun;38(3):181-186.
- doi: 10.4093/dmj.2014.38.3.181
The pyruvate dehydrogenase complex (PDC) is an emerging target for the treatment of metabolic syndrome. To maintain a steady-state concentration of adenosine triphosphate during the feed-fast cycle, cells require efficient... -
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- Pyruvate Dehydrogenase Kinase as a Potential Therapeutic Target for Malignant Gliomas
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Jha MK, Suk K
- KMID: 2048476
- Brain Tumor Res Treat.
- 2013 Oct;1(2):57-63.
- doi: 10.14791/btrt.2013.1.2.57
Metabolic aberrations in the form of altered flux through key metabolic pathways are the major hallmarks of several life-threatening malignancies including malignant gliomas. These adaptations play an important role in... -
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- A case of lactic acidosis caused by thiamine deficiency
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Byun SW, Choi SH, Park HG, Kim BJ, Kim EY, Lee KH, Yang WS
- KMID: 2257834
- Korean J Med.
- 2007 Oct;73(4):443-447.
Lactic acidosis commonly occurs in association with shock. We encountered lactic acidosis in a patient with normal blood pressure. The patient was a 17 year-old man with acute lymphocytic leukemia.... -
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- The Effects of Enflurane and Isoflurane on Hepatic Functins in Children with Hepatic Dysfunction
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Kim CS, Kang H, Kim HK, Chung IY, Kim YC
- KMID: 2239262
- Korean J Anesthesiol.
- 1993 Apr;26(2):321-325.
- doi: 10.4097/kjae.1993.26.2.321
The effects of enflurane and isoflurane on the postoperative hepatic function were compared in 39 pediatric patients with preoperative mild abnormal hepatic functions. The pediatric patients were divided randomly into... -
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- The Hepatotoxicity and Testicular Toxicity Induced by Arecoline in Mice and Protective Effects of Vitamins C and E
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Zhou J, Sun Q, Yang Z, Zhang J
- KMID: 2285503
- Korean J Physiol Pharmacol.
- 2014 Apr;18(2):143-148.
- doi: 10.4196/kjpp.2014.18.2.143
Arecoline is a major alkaloid of areca nuts which are widely chewed by southeast Asian and it manifests various toxic effects in different organs of human and animals. In this... -
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- The effects of intracellular monocarboxylates on the ATP-sensitive potassium channels in rabbit ventricular myocytes
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Kim N, Han J, Kim YE, Ho WK, Earm YE
- KMID: 2071538
- Korean J Physiol Pharmacol.
- 1998 Oct;2(5):581-589.
A regulating mechanism of the ATP-sensitive potassium channels (KATP channels) is yet to fully explained. This study was carried out to investigate the effects of intracellular application of monocarboxylates (acetate, formate, lactate, and... -
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- Quantification of Organic Acids in Amniotic Fluid for Prenatal Diagnosis of Organic Acidemia
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Koh CB, Shin DS, Bae EJ, Park WI, Lee KJ, Lee HJ, Jo Y, Lee SW, Noh US
- KMID: 2073200
- Korean J Pediatr.
- 2004 Oct;47(10):1047-1052.
PURPOSE: Since 1997, the quantification of organic acids in urine has become possible in Korea. This helped to diagnose a great variety of inborn errors of metabolism. However, we still... -
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- Organic acidemias in Korea
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Lee HJ
- KMID: 2168073
- Hanyang Med Rev.
- 2005 Aug;25(3):49-64.
Since we started organic acid analysis in July 1997, we have collected data about organic acidemias in Korea. The data presented herein constitute our 3 years experience in organic acid... -
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- Dietary effect of green tea extract on epidermal levels of skin pH related factors, lactate dehydrogenase protein expression and activity in UV-irradiated hairless mice
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Lee B, Kim J, Hwang J, Cho Y
- KMID: 2209843
- J Nutr Health.
- 2016 Apr;49(2):63-71.
- doi: 10.4163/jnh.2016.49.2.63
PURPOSE: Skin pH, an indicator of skin health, is maintained by various organic factors, which include lactate, free amino acid (FAA), and free fatty acid (FFA). As skin ages or... -
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- The Role of HMGB1 and the Effect of Ethyl Pyruvate on Ischemia and Reperfusion Injury of Rat Kidney
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Chung KY, Park JJ, Kim YS
- KMID: 2201877
- J Korean Soc Transplant.
- 2007 Dec;21(2):234-240.
PURPOSE: High mobility group box-1 (HMGB1) was identified as a DNA binding protein that functions as a co-factor for proper transcriptional regulation in somatic cells. Extra- cellular HMGB1 acts as... -
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