- The First Korean Case of Candidemia due to Candida dubliniensis
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Yu N, Kim HR, Lee MK
- KMID: 1381690
- Ann Lab Med.
- 2012 May;32(3):225-228.
- doi: 10.3343/alm.2012.32.3.225
Candidemia due to uncommon Candida spp. appears to be increasing in incidence. C. dubliniensis has been increasingly recovered from individuals not infected with HIV. Identification of C. dubliniensis can be... -
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- beta-TrCP1 degradation is a novel action mechanism of PI3K/mTOR inhibitors in triple-negative breast cancer cells
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Yi YW, Kang HJ, Bae EJ, Oh S, Seong YS, Bae I
- KMID: 2155408
- Exp Mol Med.
- 2015 Feb;47(2):e143.
- doi: 10.1038/emm.2014.127
An F-box protein, beta-TrCP recognizes substrate proteins and destabilizes them through ubiquitin-dependent proteolysis. It regulates the stability of diverse proteins and functions as either a tumor suppressor or an oncogene.... -
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- AMP kinase/cyclooxygenase-2 pathway regulates proliferation and apoptosis of cancer cells treated with quercetin
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Lee YK, Park SY, Kim YM, Lee WS, Park OJ
- KMID: 1123467
- Exp Mol Med.
- 2009 Mar;41(3):201-207.
- doi: 10.3858/emm.2009.41.3.023
AMPK (AMP-activated protein kinase) is highly conserved in eukaryotes, where it functions primarily as a sensor of cellular energy status. Recent studies indicate that AMPK activation strongly suppresses cell proliferation... -
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- Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells
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Jeong KJ, Park SY, Seo JH, Lee KB, Choi WS, Han JW, Kang JK, Park CG, Kim YK, Lee HY
- KMID: 1072941
- Exp Mol Med.
- 2008 Dec;40(6):607-616.
- doi: 10.3858/emm.2008.40.6.607
Lysophosphatidic acid (LPA) is a bioactive phospholipids and involves in various cellular events, including tumor cell migration. In the present study, we investigated LPA receptor and its transactivation to EGFR... -
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- CD98 activation increases surface expression and clusteringof beta 1 integrins in MCF-7 cells through FAK/Src- and cytoskeleton-independent mechanisms
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Kim SM, Hahn JH
- KMID: 756327
- Exp Mol Med.
- 2008 Jun;40(3):261-270.
- doi: 10.3858/emm.2008.40.3.261
CD98, a disulfide-linked 125-kDa heterodimeric type II transmembrane glycoprotein, regulates beta 1 integrin- mediated cell adhesion. However, the molecular mechanisms underlying CD98-mediated activation of beta 1 integrin are presently unclear.... -
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- Species Distribution and Susceptibility to Azole Antifungals of Candida Bloodstream Isolates from Eight University Hospitals in Korea
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Lee JS, Shin JH, Lee K, Kim MN, Shin BM, Uh Y, Lee WG, Lee HS, Chang CL, Kim SH, Shin MG, Suh SP, Ryang DW
- KMID: 1122614
- Yonsei Med J.
- 2007 Oct;48(5):779-786.
- doi: 10.3349/ymj.2007.48.5.779
PURPOSE: The incidence of Candida bloodstream infections (BSI) has increased over the past two decades. The rank order of occurrence and the susceptibility to antifungals of the various Candida... -
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- Functional involvement of src and focal adhesion kinase in a CD99 splice variant-induced motility of human breast cancer cells.
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Lee HJ, Kim ES, Jee BE, Hahn JH, Han KH, Jung KC, Park SH, Lee HS
- KMID: 1380225
- Exp Mol Med.
- 2002 Jul;34(3):177-183.
Earlier report showed that expression of a splice variant of CD99 transmembrane protein increases invasive ability of human breast cancer cells. Cell motility was also significantly enhanced by the CD99... -
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- Species Distribution and Antifungal Susceptibilities of Yeast Clinical Isolates from Three Hospitals in Korea, 2001 to 2007
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Lee MK, Yong D, Kim M, Kim MN, Lee K
- KMID: 1781642
- Korean J Lab Med.
- 2010 Aug;30(4):364-372.
- doi: 10.3343/kjlm.2010.30.4.364
BACKGROUND: We utilized results from the ARTEMIS DISK Global Antifungal Surveillance Program to evaluate the species distribution and fluconazole and voriconazole susceptibilities of yeast isolates from clinical specimens in South... -
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- Signaling pathway for 2,3,7,8-tetrachlorodibenzo- p-dioxin-induced TNF-alpha production in differentiated THP-1 human macrophages
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Cheon HJ, Woo YS, Lee JY, Kim HS, Kim HJ, Cho S, Won NH, Sohn J
- KMID: 756076
- Exp Mol Med.
- 2007 Aug;39(4):524-534.
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a prototypic halogenated aromatic hydrocarbon (HAH), is known as one of the most potent toxicants. At least a part of its toxic effects appears to be derived from... -
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