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Research Support, U.S. Gov't, P.H.S.

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1 Development of inhibitors of pyrimidine metabolism

Cha S

KMID: 1105559
Yonsei Med J.
1989 Dec;30(4):315-326.
doi: 10.3349/ymj.1989.30.4.315

Benzylacyclouridines were developed as specific and potent competitive inhibitors of uridine phosphorylase with Ki values in the nanomolar range. These compounds have no activity against thymidine phosphorylase, uridine kinase,...

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