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Pyridoxine induced neuropathy by subcutaneous administration in dogs

Chung JY, Choi JH, Hwang CY, Youn HY

To construct a sensory neuropathy model, excess pyridoxine (150 mg/kg s.i.d.) was injected subcutaneously in dogs over a period of 7 days. During the administrations period, the dogs experienced body...
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In vitro and in vivo gene therapy with CMV vector-mediated presumed dog beta-nerve growth factor in pyridoxine-induced neuropathy dogs

Chung JY, Choi JH, Shin IS, Choi EW, Hwang CY, Lee SK, Youn HY

Due to the therapeutic potential of gene therapy for neuronal injury, many studies of neurotrophic factors, vectors, and animal models have been performed. The presumed dog beta-nerve growth factor (pdbeta-NGF)...
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