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Mechanism of 2-Deoxy-D-ribose-induced Damage in Pancreatic beta-cells

Koh G, Woo JT, Lee DH, Oh S, Kim SW, Kim JW, Kim YS, Park DB

BACKGROUND: Mechanism for glucose toxicity is known to be an increased oxidative stress produced by multiple pathways. In our previous report, 2-deoxy-d-ribose (dRib) promoted apoptosis by increasing oxidative stress in...
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