- A Case of Complete Regression of Hepatocellular Carcinoma during Administration of COX-2 Inhibitor
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Song HJ, Kim YS, Han CH, Jang JY, Kim JH, Cheon YK, Kim YS, Moon JH, Cho YD, Shim CS, Kwon KH, Kim BS
- KMID: 760678
- Korean J Hepatol.
- 2006 Sep;12(3):449-454.
Overexpression of cyclooxygenase-2 (COX-2) has been associated with hepatocarcinogenesis. Inhibitors of COX-2 have proapoptotic and antiproliferative effects on malignant tumors and inhibit tumor invasion to the surrounding tissues. We report... -
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- Cyclooxygenase-2 inhibitors modulate skin aging in a catalytic activity-independent manner
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Lee ME, Kim SR, Lee S, Jung YJ, Choi SS, Kim WJ, Han JA
- KMID: 1389733
- Exp Mol Med.
- 2012 Sep;44(9):536-544.
It has been proposed that the pro-inflammatory catalytic activity of cyclooxygenase-2 (COX-2) plays a key role in the aging process. However, it remains unclear whether the COX-2 activity is a... -
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