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Effects of Celecoxib and Nordihydroguaiaretic Acid on Puromycin Aminonucleoside-Induced Nephrosis in the Rat

Lee DW, Kwak IS, Lee SB, Song SH, Seong EY, Chung HC, Yang BY, Lee MY, Sol MY

The selective cyclooxygenase-2 (COX-2) and 5-lipoxygenase (LOX) inhibitors might inhibit prostaglandin synthesis and reduce proteinuria. The present study was designed to investigate the anti-proteinuric effects of nordihydroguaiaretic acid (NDGA) as...
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Role of p21CIP1 as a determinant of SC-560 response in human HCT116 colon carcinoma cells

Lee E, Choi MK, Han IO, Lim SJ

  • KMID: 1094159
  • Exp Mol Med.
  • 2006 Jun;38(3):325-331.
SC-560, a strucutral analogue of celecoxib, induces growth inhibition in a wide range of human cancer cells in a cyclooxygenase (COX)-independent manner. Since SC-560 suppresses the growth of cancer cells...
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Heterogeneous nuclear ribonuclear protein C is increased in the celecoxib-induced growth inhibition of human oral squamous cell carcinoma

Lee EJ, Kim SH, Kwark YE, Kim J

  • KMID: 1094145
  • Exp Mol Med.
  • 2006 Jun;38(3):203-209.
Celecoxib is a selective inhibitor of cyclooxygenase-2 (COX-2) that is a critical factor in carcinogenesis, but precise mechanism of its action remains to be elucidated. Here we evaluated the inhibitory...
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