- Influence of age and sex on pseudocholinesterase activity of Korean adults
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Cho DS, In CH
- KMID: 1752556
- Korean J Anesthesiol.
- 1994 May;27(5):473-477.
- doi: 10.4097/kjae.1994.27.5.473
Serum pseudocholinesterase activities, using butyrylthiocholine as substrate, measured in 639 employees of Korea Cancer Center Hospital in 1993. Overall mean value of pseudocholinesterase was 9.38+/-2.10 U/ml, 10.6+/-2.10 U/ml in male,... -
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- Changes in Psedocholinesterase Activity Following IV Bolus Administration of Succinylcholine
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Jee DL, Bae JI, Cheun JK
- KMID: 1933175
- Korean J Anesthesiol.
- 1988 Apr;21(2):318-320.
- doi: 10.4097/kjae.1988.21.2.318
Plasma cholinesterase was assayed during the period immediately following IV bolus injection of succinylcholine 1mg/kg to test the effect of succinylcholine on pseudocholinesterase activity. Twenty healthy adult patients scheduled for... -
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- Inhibition Numbers of Pseudocholinesterase in Korean Adults
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Cho DS, Lee NK, Kim CG, Lee HL, Hong SI
- KMID: 2237870
- Korean J Anesthesiol.
- 1995 Aug;29(2):233-237.
- doi: 10.4097/kjae.1995.29.2.233
Pseudocholinesterase is an essential enzyme for hydrolysis of succinylcholine and some people has low activity. The pseudocholinesterase from a normal individual has a greater apparent affinity for the cholinester substrate... -
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- Modification of Atracurium or Vecuronium Blockade and Their Reversal by Succinylcholine in the Cat
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Shin YS, Yoo ES, Min SK, Kim JR, Park KW
- KMID: 2240576
- Korean J Anesthesiol.
- 1992 Apr;25(2):260-265.
- doi: 10.4097/kjae.1992.25.2.260
The interaction between succinylcholine(SCC) and non-depolarizer; atracurium or vecuronium, was investigated in 36 cats of either sex using the sciatic nerve-anterior tibialis muscle preparation. And also, its relation to the... -
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- Comparison of Pseudocholinesterase Activity between Nonpregnant and Term-pregnant Women with the Genotypically Normal Enzyme
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Park SJ, Baik HJ, Kim KS, Cho DS
- KMID: 2091024
- Korean J Anesthesiol.
- 1996 Nov;31(5):613-618.
- doi: 10.4097/kjae.1996.31.5.613
BACKGROUND: Many reports on the change of pseudocholinesterase activity in pregnant women showed that it declines during pregnancy and in the immediate postpartum period. In Korea, there are two papers... -
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- Delayed recovery from paralysis by succinylcholine in patient with preoperatively unrecognized and inherited pseudocholinesterase deficiency
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Ok SH, Woo MK, Kim CG, Hwang I, Sohn JT
- KMID: 1965338
- Korean J Anesthesiol.
- 2013 Dec;65(6 Suppl):S19-S20.
- doi: 10.4097/kjae.2013.65.6S.S19
No abstract available. -
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- The Effects of Hypothermic Hemodilutional Cardiopulmonary Bypass on the Pseudocholinesterase Level
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Chae BK, Lee HW, Chang SH
- KMID: 2033162
- Korean J Anesthesiol.
- 1995 May;28(5):648-654.
- doi: 10.4097/kjae.1995.28.5.648
Pseudocholinesterase is known to be involved in the metabolism of succinylcholine, mivacurium, procaine, chloroprocaine, tetracaine, cocaine, heroin, and other drugs, although the physiologic function has not been well established. Prolonged... -
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- Effects of Edrophonium and/or Pseudocholinesterase for the Reversal of Mivacurium-Induced Paralysis in vitro
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Park DH, Seong KW, Jeong WY, Kim HK, Yang HS
- KMID: 2039808
- Korean J Anesthesiol.
- 2002 Feb;42(2):213-220.
- doi: 10.4097/kjae.2002.42.2.213
BACKGROUND: Mivacurium is a nondepolarizing neuromuscular blocking agent hydrolyzed by pseudocholinesterase. Anticholinesterase used in the reversal of mivacurium-induced muscle relaxation may also inhibit plasma pseudocholinesterase, and delay hydrolysis... -
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- The Effects of Ethanol on Cholinesterase Inactivation by Organophosphorous
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Choi HC, Kim JH, Ha JH, Lee KY, Kim WJ, Woo HJ, Huh CU, Son SM, Chun EJ
- KMID: 2320290
- Yeungnam Univ J Med.
- 1999 Dec;16(2):326-332.
BACKGROUND: In korea the agricultural community widely uses organophosphorous, and organophosphorous poisonings are increasing every year. We compared change in activity of acetylcholinesterase and pseudocholinesterase by organophosphorous and by the interaction... -
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- Effects of Pseudocholinesterase and/or Neostigmine, Pyridostigmine, Edrophonium and Galanthamine for Reversal of Mivacurium- or Succinylcholine-induced Paralysis in Vitro
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Cho SS, Yoon SN, Choi Y, Yang HS, Han SM, Kim SY, Suh BT
- KMID: 2031567
- Korean J Anesthesiol.
- 2000 Aug;39(2):232-242.
- doi: 10.4097/kjae.2000.39.2.232
BACKGROUND: The hydrolysis of mivacurium and succinylcholine is impaired in the presence of defects of pseudocholinesterase. Clinical reports are conflicting as to the utility of anticholinesterases, in the reversal of... -
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- Effects of Anticholinesterases on the Neuromuscular Blocking Action of Suecinylcholine
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Moon BK, Shin YS, Park KW, Cho CH
- KMID: 1933264
- Korean J Anesthesiol.
- 1987 Oct;20(5):637-642.
- doi: 10.4097/kjae.1987.20.5.637
The interaction between succinylcholine (SCC) and anticholinegterase drugs is illustrated by the inhibition of acetylcholine hydrolysis or a decrease in pseudocholinesterase activity- The present study was performed in order to... -
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- Effects of Pseudocholinesterase, Anticholinesterase, and 4-Aminopyridine to the Mivacurium-induced Neuromuscular Block on Rat Diaphragm
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Kim YI, Kang KS, Hwang KH, Yang HS, Kim SY, Song JE
- KMID: 2237746
- Korean J Anesthesiol.
- 1997 Jun;32(6):865-873.
- doi: 10.4097/kjae.1997.32.6.865
BACKGROUND: Prolongation of the neuromuscular block of mivacurium can occur when there is a genetic deficiency of the enzyme or in the presence of anticholinesterase (AntiChE) which inhibit the activity... -
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- A Case of Amitraz Poisoning Initially Misdiagnosed as Acute Organophosphate Insecticide Poisoning
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Cho Y, Kim JW
- KMID: 2317669
- Soonchunhyang Med Sci.
- 2012 Dec;18(2):151-154.
Amitraz is acaricidal and insecticidal pesticide used worldwide to control ticks and mites in plants and animals. Amitraz poisoning is characterized by clinical toxidrome such as central nervous system, respiratory... -
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- The Pharmacokinetic Response of Succinylcholine from Blood Flow occlusion
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Yoon SJ, Kim CS, Cha YD, Kim YI, Kang KS, Kim SY
- KMID: 2239205
- Korean J Anesthesiol.
- 1994 Feb;27(2):155-158.
- doi: 10.4097/kjae.1994.27.2.155
There is a direct relationship between the plasma concentration of the drugs and the magnitude of neuromuscular blockade in non-depolarizing neuromuscular blocking agents. But the classical pharmacokinetic data of succinylcholine... -
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- The Infusion Rate of Mivacurium for Cesarean Section and its Spontaneous Recovery
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Kim JH, Ahn EK, Shin YS, Byun H
- KMID: 1860395
- Korean J Anesthesiol.
- 1996 Feb;30(2):198-205.
- doi: 10.4097/kjae.1996.30.2.198
BACKGROUND: Mivacurium is a nondepolarizing muscle relaxant and metabolized by pseudo-cholinesterase(pChe). Many reports show fall in pChe activity during pregnancy, so the metabolism of mivacurium may be delayed and muscle... -
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- Comparison of Pharmacokinetic Affinity of Various Non-depolarizing Neuromuscular Blocking Agents in the Isolated Foream
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Lee SK, Jeon YS, Ahn JS, Hwang KH, Park W, Kim SY
- KMID: 2013189
- Korean J Anesthesiol.
- 1995 Jun;28(6):816-820.
- doi: 10.4097/kjae.1995.28.6.816
It is well known that the plasma concentration is important in determining the rate of recovery from neuromuscular block. However, nondepolarizing neuromuscular blockade are retained at the neuromuscular junction and... -
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- Effects of Mivacurium in the Patients with Myasthenia Gravis
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Kim DY, Park SH, Lim TH, Lee EJ, Yang HS
- KMID: 1936246
- Korean J Anesthesiol.
- 2001 Jun;40(6):716-720.
- doi: 10.4097/kjae.2001.40.6.716
BACKGROUND: Myasthenia gravis is an autoimmune neuromuscular disorder that shows increased sensitivity to nondepolarizing muscle relaxants. Mivacurium chloride is a short acting nondepolarizing neuromuscular blocker and a benzylisoquinolin diester... -
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- Relative Risk and Clinical Severity Assessment in Patients with Non-Oral Route Organophosphate Poisoning Compared with Oral Route Poisoning
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Jung WJ, Yu MH, Lee Y, Kim H, Cha YS, Park KH
- KMID: 2419733
- Yonsei Med J.
- 2018 Oct;59(8):982-988.
- doi: 10.3349/ymj.2018.59.8.982
PURPOSE: Organophosphates, commonly used in agricultural pesticides, pose high risks and incidences of poisoning. In the present study, we investigated the relative risk and clinical severity, including laboratory results, of... -
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- Pharmacodynamic Changes of Mivacurium in Liver Cirrhosis Model in Rabbits Using Carbon Tetrachloride Intoxication
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Cha YD, Lee HS, Ki HY, Park HJ, Yang CW, Kim YH, Kim KS, Han JU
- KMID: 2299079
- Korean J Anesthesiol.
- 2004 Jun;46(6):708-713.
- doi: 10.4097/kjae.2004.46.6.708
BACKGROUND: A reproducible animal model of liver cirrhosis by administering multiple doses of carbon tetrachloride (CCl4) is highly desirable for appropriate metabolic and therapeutic studies. The current study was undertaken... -
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- A Study on Organophosphate Poisoning Patients: Comparison of the Survivor Group and Dead Group
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Choi YG, Lee DH, Kim WH, Lee GW, Kim SP, Kim SJ, Cho SH, Cho NS
- KMID: 2204091
- J Korean Soc Clin Toxicol.
- 2010 Jun;8(1):16-23.
PURPOSE: Organophosphate insecticide poisoning is common in Korea, but there is no definitive guideline for determining the severity of the poisoning and the predictive factors. Therefore, we evaluated the organophosphate... -
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