- A Case of Medullary Thyroid Carcinoma with de novo V804M RET Germline Mutation
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Choi YS, Kwon HJ, Kim BK, Kwon SK, Park YH, Kim JH, Jung SB, Lee CH, Lee SK, Uchino S
- KMID: 2158016
- J Korean Med Sci.
- 2013 Jan;28(1):156-159.
- doi: 10.3346/jkms.2013.28.1.156
Many cases of RET proto-oncogene mutations of hereditary medullary thyroid carcinoma (MTC) have been reported in Korea. However, MTC with V804M RET proto-oncogene germline mutations have not been reported in... -
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- A Korean Family of Familial Medullary Thyroid Cancer with Cys618Ser RET Germline Mutation
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Jung J, Uchino S, Lee Y, Park H
- KMID: 1779251
- J Korean Med Sci.
- 2010 Feb;25(2):226-229.
- doi: 10.3346/jkms.2010.25.2.226
Familial medullary thyroid carcinoma (FMTC) is caused by autosomal dominant gain-of-function mutations in the RET proto-oncogene. An identifiable RET mutation can be detected in about 85% of FMTC families. The... -
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- RET Fusion Genes in Korean Non-Small Cell Lung Cancer
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Yoo SS, Jin G, Jung HJ, Hong MJ, Choi JE, Jeon HS, Lee SY, Lim JO, Park JY
- KMID: 1777699
- J Korean Med Sci.
- 2013 Oct;28(10):1555-1558.
- doi: 10.3346/jkms.2013.28.10.1555
Recently, rearranged during transfection (RET) fusions have been identified in approximately 1% of non-small cell lung cancer (NSCLC). To know the prevalence of RET fusion genes in Korean NSCLCs, we... -
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- A case of breast cancer in a patient with multiple endocrine neoplasia type 2
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Roh JM, Lee YB, An HR, Shim WH, Lee EH, Hong SW, Cho MH
- KMID: 2259348
- Korean J Med.
- 2010 Oct;79(4):432-437.
Multiple Endocrine Neoplasia Type 2 (MEN2) is a rare hereditary complex disorder characterized by the presence of medullary thyroid carcinoma, pheochromocytoma, and other hyperplasias or neoplasias of different endocrine tissues... -
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- EGF Induced RET Inhibitor Resistance in CCDC6-RET Lung Cancer Cells
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Chang H, Sung JH, Moon SU, Kim HS, Kim JW, Lee JS
- KMID: 2374183
- Yonsei Med J.
- 2017 Jan;58(1):9-18.
- doi: 10.3349/ymj.2017.58.1.9
PURPOSE: Rearrangement of the proto-oncogene rearranged during transfection (RET) has been newly identified potential driver mutation in lung adenocarcinoma. Clinically available tyrosine kinase inhibitors (TKIs) target RET kinase activity, which... -
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- The 5-hydroxytryptamine 4 Receptor Agonist-induced Actions and Enteric Neurogenesis in the Gut
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Takaki M, Goto K, Kawahara I
- KMID: 2381146
- J Neurogastroenterol Motil.
- 2014 Jan;20(1):17-30.
We explored a novel effect of 5-hydroxytryptamine 4 receptor (5-HT4R) agonists in vivo to reconstruct the enteric neural circuitry that mediates a fundamental distal gut reflex. The neural circuit insult... -
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