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Activation of the intrinsic mitochondrial apoptotic pathway in swine influenza virus-mediated cell death

Choi YK, Kim TK, Kim CJ, Lee JS, Oh SY, Joo HS, Foster DN, Hong KC, You S, Kim H

  • KMID: 1105272
  • Exp Mol Med.
  • 2006 Feb;38(1):11-17.
The mitochondrial pathway of swine influenza virus (SIV)-induced apoptosis was investigated using porcine kidney (PK-15) cells, swine testicle (ST) cells, and HeLa cervical carcinoma cells which are known not to...
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Enhancement of radiosensitivity by combined ceramide and dimethylsphingosine treatment in lung cancer cells

Park HW, Song JY, Kim KS, Han Y, Kim CW, Yi SY, Yun YS

  • KMID: 1123762
  • Exp Mol Med.
  • 2004 Oct;36(5):411-419.
Ceramide generated from sphingomyelin in response to ionizing radiation has been implicated as a second messenger to induce cellular proapoptotic signals. Both ceramide and its metabolic inhibitor, N, N-dimethyl-D-erythro-sphingosine (DMS),...
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Endothelin A Receptor Blockade Influences Apoptosis and Cellular Proliferation in the Developing Rat Kidney

Yoo KH, Yim HE, Jang GY, Bae IS, Choi BM, Hong YS, Lee JW

Endothelin systems are believed to play important roles in the emergence and maintenance of functions of various organs during perinatal development, including the kidney. The present study was designed to...
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Capsaicin-Induced Apoptosis of FaDu Human Pharyngeal Squamous Carcinoma Cells

Le TD, Jin DC, Rho SR, Kim MS, Yu R, Yoo H

PURPOSE: To investigate the anti-tumor effect of capsaicin on human pharyngeal squamous carcinoma cells (FaDu). MATERIALS AND METHODS: The expression of apoptosis/cell cycle-related proteins (or genes) was examined by reverse transcriptase-polymerase...
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ATM modulates transcription in response to histone deacetylase inhibition as part of its DNA damage response

Jang ER, Choi JD, Park MA, Jeong G, Cho H, Lee JS

Chromatin structure has a crucial role in a diversity of physiological processes, including development, differentiation and stress responses, via regulation of transcription, DNA replication and DNA damage repair. Histone deacetylase...
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