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STAT3 is involved in phosphatidic acid-induced Bcl-2 expression in HeLa cells

Choi HJ, Lee JH, Park SY, Cho JH, Han JS

Phosphatidic acid (PA), the product of a PLD-mediated reaction, is a lipid second messenger that participates in various intracellular signaling events and is known to regulate a growing list of...
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Immunohistochemical Expression of p53, Bcl-2, and Ki-67 Proteins in Traditional Serrated Adenomas of Colon

Jung JH, Kwon HJ, Kim TJ, Cho HJ, Kim HK, Cheung DY, Kim JI, Kim JK

BACKGROUND/AIMS: Serrated adenomas of the colon show mixed characteristics of both hyperplastic and adenomatous polyps. Serrated adenomas are known to progress via the serrated pathway than the adenoma-carcinoma pathway. The...
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Effects of Bevacizumab on Bcl-2 Expression and Apoptosis in Retinal Pigment Epithelial Cells under Oxidative Stress

Kim S, Kim YJ, Kim NR, Chin HS

PURPOSE: To evaluate the effects of bevacizumab on expression of B-cell leukemia/lymphoma (Bcl)-2 and apoptosis in retinal pigment epithelial (RPE) cells under oxidative stress conditions. METHODS: RPE cells were treated with...
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Stanniocalcin-1 protects bovine intestinal epithelial cells from oxidative stress-induced damage

Wu LM, Guo R, Hui L, Ye YG, Xiang JM, Wan CY, Zou M, Ma R, Sun XZ, Yang SJ, Guo DZ

Chronic enteritis can produce an excess of reactive oxygen species resulting in cellular damage. Stanniocalcin-1(STC-1) reportedly possesses anti-oxidative activity, the aim of this study was to define more clearly the...
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Apoptosis, bcl2 expression, and cell cycle analyses in nickel(II)-treated normal rat kidney cells

Lee SH, Choi JG, Cho MH

Nickel compounds are carcinogenic to human and are potent inducers of kidney and lung tumors in experimental animals. In this study, the effects of nickel(II) acetate on apoptosis, cell cycle...
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