- Brain site-specific proteome changes in aging-related dementia
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Manavalan , Mishra M, Feng L, Sze SK, Akatsu H, Heese K
- KMID: 2154258
- Exp Mol Med.
- 2013 Sep;45(9):e39.
This study is aimed at gaining insights into the brain site-specific proteomic senescence signature while comparing physiologically aged brains with aging-related dementia brains (for example, Alzheimer's disease (AD)). Our study... -
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- Exogenous rhTRX reduces lipid accumulation under LPS-induced inflammation
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Han GY, Lee EK, Park HW, Kim HJ, Kim CW
- KMID: 2155336
- Exp Mol Med.
- 2014 Jan;46(1):e71.
- doi: 10.1038/emm.2013.136
Redox-regulating molecule, recombinant human thioredoxin (rhTRX) which shows anti-inflammatory, and anti-oxidative effects against lipopolysaccharide (LPS)-stimulated inflammation and regulate protein expression levels. LPS-induced reactive oxygen intermediates (ROI) and NO production were... -
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- Polymorphisms of COTL1 gene identified by proteomic approach and their association with autoimmune disorders
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Jin EH, Shim SC, Kim HG, Chae SC, Chung HT
- KMID: 1123810
- Exp Mol Med.
- 2009 May;41(5):354-361.
- doi: 10.3858/emm.2009.41.5.040
To select candidate genes, we attempted to comparative analysis of protein levels between rheumatoid arthritis (RA) patients and healthy controls by two-dimensional electrophoresis (2-DE) and matrix-assisted laser desorption ionization mass... -
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