- Dissecting the molecular mechanism of nuclear receptor action: transcription coactivators and corepressors
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Lee JW, Cheong JH, Lee YC, Na SY, lee SK
- KMID: 1109302
- Exp Mol Med.
- 2000 Jun;32(2):53-60.
No abstract available. -
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- CTCF as a multifunctional protein in genome regulation and gene expression
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Kim S, Yu NK, Kaang BK
- KMID: 2155420
- Exp Mol Med.
- 2015 Jun;47(6):e166.
- doi: 10.1038/emm.2015.33
CCCTC-binding factor (CTCF) is a highly conserved zinc finger protein and is best known as a transcription factor. It can function as a transcriptional activator, a repressor or an insulator... -
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- Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies
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Ciechanover A, Kwon YT
- KMID: 2155412
- Exp Mol Med.
- 2015 Mar;47(3):e147.
- doi: 10.1038/emm.2014.117
Mammalian cells remove misfolded proteins using various proteolytic systems, including the ubiquitin (Ub)-proteasome system (UPS), chaperone mediated autophagy (CMA) and macroautophagy. The majority of misfolded proteins are degraded by the... -
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- The proteins of synaptic vesicle membranes are affected during ageing of rat brain
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Lee SR, Kim AR, Kim JS, Kim JB, Lee JY, Lee YL, Choe M, Park JB
- KMID: 1457533
- Exp Mol Med.
- 2001 Dec;33(4):220-225.
Low molecular weight GTP-binding proteins are molecular switches that are believed to play pivotal roles in cell growth, differentiation, cytoskeletal organization, and vesicular trafficking. Rab proteins are key players in... -
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- Conjugation and deconjugation of ubiquitin regulating the destiny of proteins
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Baek KH
- KMID: 1088651
- Exp Mol Med.
- 2003 Feb;35(1):1-7.
The homeostasis for a number of cellular proteins is regulated by not only phosphorylation and dephosphorylation, but also ubiquitination and deubiquitination. A number of proteins involved in the degradation of... -
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- Properties of GST-CALM expressed in E. coli
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Kim JA, Kim SR, Jung YK, Woo SY, Seoh JY, Hong YS, Kim HL
- KMID: 1109309
- Exp Mol Med.
- 2000 Jun;32(2):93-99.
Clathrin-coated vesicles (CCVs) are involved in protein and lipid trafficking between intracellular compartments in eukaryotic cells. CCVs are composed of clathrin and assembly proteins. The clathrin assembly protein lymphoid... -
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- Control of Na+ channels in salivary duct cells
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Dinudom A, Komwatana , Young J, Cook D
- KMID: 1026942
- J Korean Med Sci.
- 2000 Aug;15(Suppl):S31-S33.
- doi: 10.3346/jkms.2000.15.S.S31
No abstract available. -
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- G protein signaling in the parasite Entamoeba histolytica
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Bosch DE, Siderovski DP
- KMID: 2154234
- Exp Mol Med.
- 2013 Mar;45(3):e15.
The parasite Entamoeba histolytica causes amebic colitis and systemic amebiasis. Among the known amebic factors contributing to pathogenesis are signaling pathways involving heterotrimeric and Ras superfamily G proteins. Here, we... -
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- Phosphorylation of 46-kappa Da protein of synaptic vesicle membranes is stimulated by GTP and Ca2+/calmodulin
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Kim AR, Choi WH, Lee SR, Kim JS, Jeon CY, Kim JI, Kim JB, Lee JY, Kim EG, Park JB
- KMID: 1121097
- Exp Mol Med.
- 2002 Dec;34(6):434-443.
The release of neurotransmitter is regulated in the processes of membrane docking and membrane fusion between synaptic vesicles and presynaptic plasma membranes. Synaptic vesicles contain a diverse set of... -
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- Expression of Glycolysis-Related Proteins in Solid Papillary Carcinoma of the Breast According to Basement Membrane Status
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Kwon JE, Jung WH, Koo JS
- KMID: 2068665
- Yonsei Med J.
- 2014 May;55(3):576-583.
- doi: 10.3349/ymj.2014.55.3.576
PURPOSE: The aim of this study was to investigate the differences of expression in glycolysis-related proteins such as Glut-1, carbonic anhydrase (CA) IX, and monocarboxylate transporter (MCT) 4 according to... -
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- Intrinsic Cellular Defenses against Virus Infection by Antiviral Type I Interferon
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Boo KH, Yang JS
- KMID: 1779600
- Yonsei Med J.
- 2010 Jan;51(1):9-17.
- doi: 10.3349/ymj.2010.51.1.9
Intrinsic cellular defenses are non-specific antiviral activities by recognizing pathogen-associated molecular patterns (PAMPs). Toll-like receptors (TLRs), one of the pathogen recognize receptor (PRR), sense various microbial ligands. Especially, TLR2, TLR3,... -
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- Toward understanding the role of the neuron-specific BAF chromatin remodeling complex in memory formation
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Choi KY, Yoo M, Han JH
- KMID: 2070274
- Exp Mol Med.
- 2015 Apr;47(4):e155.
- doi: 10.1038/emm.2014.129
The long-term storage of memory requires the finely tuned coordination of intracellular signaling with the transcriptional, translational and epigenetic regulations of gene expression. Among the epigenetic mechanisms, however, we know... -
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- The expressions of HSP70 and alphaB-crystallin in myocarditis associated with foot-and-mouth disease virus in lambs
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Gulbahar M, Kabak YB, Karayigit , Yarim M, Guvenc T, Parlak U
- KMID: 1067339
- J Vet Sci.
- 2011 Mar;12(1):65-73.
- doi: 10.4142/jvs.2011.12.1.65
This study describes the expression of heat shock protein70 (HSP70) and alpha-basic-crystallin (alpha-BC) and their association with apoptosis and some related adaptor proteins in the pathogenesis of foot-and-mouth disease virus... -
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- Enzymology of Protein Methylation
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Paik WK, Kim S
- KMID: 693029
- Yonsei Med J.
- 1986 Sep;27(3):159-177.
- doi: 10.3349/ymj.1986.27.3.159
No abstract available. -
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- Bricks and mortar of the epidermal barrier
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Nemes Z, Steinert P
- KMID: 755021
- Exp Mol Med.
- 1999 Mar;31(1):5-19.
A specialized tissue type, the keratinizing epithelium, protects terrestrial mammals from water loss and noxious physical, chemical and mechanical insults. This barrier between the body and the environment is constantly maintained by reproduction... -
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- Differential Expression of Stem Cell Markers and Vascular Endothelial Growth Factor in Human Retinoblastoma Tissue
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Kim M, Kim JH, Kim JH, Kim DH, Yu YS
- KMID: 1098791
- Korean J Ophthalmol.
- 2010 Feb;24(1):35-39.
- doi: 10.3341/kjo.2010.24.1.35
PURPOSE: To investigate the relationship between vascular endothelial growth factor (VEGF) and the cancer stem cell-vascular niche complex in human retinoblastoma tissue. METHODS: Six human retinoblastoma specimens primarily enucleated for... -
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- Insulin resistance as a key link for the increased risk of cognitive impairment in the metabolic syndrome
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Kim B, Feldman EL
- KMID: 2155414
- Exp Mol Med.
- 2015 Mar;47(3):e149.
- doi: 10.1038/emm.2015.3
Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors that includes obesity, diabetes, and dyslipidemia. Accumulating evidence implies that MetS contributes to the development and progression of Alzheimer's disease... -
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- Primary Rectal Malignant Melanoma with Rapid Progression after Complete Resection
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Kim KO, Jang BI, Kim JH, Bae YK
- KMID: 1775895
- Korean J Gastroenterol.
- 2010 Mar;55(3):151-153.
- doi: 10.4166/kjg.2010.55.3.151
No abstract available. -
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- Gastric Metastasis from Breast Cancer
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Yoon SY, Shim KN
- KMID: 1775789
- Korean J Gastroenterol.
- 2013 Jan;61(1):54-57.
- doi: 10.4166/kjg.2013.61.1.54
No abstract available. -
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- Composite Follicular Variant of Papillary Carcinoma and Mucoepidermoid Carcinoma of Thyroid Gland: A Case Report
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Jung YH, Kang MS
- KMID: 1779245
- J Korean Med Sci.
- 2010 Nov;25(11):1683-1687.
- doi: 10.3346/jkms.2010.25.11.1683
A 50-yr-old male presented a thyroid mass with dysphasia and hoarseness. He underwent total thyroidectomy and neck node dissection. Pathologically, the tumor had two distinct tumor components with intermingled areas:... -
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