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Effects of Cycloheximide and Dexamethasone on Fas - Mediated Apopthsis in Primary Human Astrocytes

Choi C, Choi IH, Huh K

  • KMID: 1550755
  • Korean J Immunol.
  • 1999 Dec;21(4):361-368.
Astrocytes are major glial cells in central nervous system (CNS) and are known to express death receptors or ligands that can induce apoptosis of astrocytes or other brain cells. We...
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Successful treatment of recurrent follicular B-cell lymphoma with clarithromycin, prednisolone, and cyclophosphamide

Ohe M, Hashino S

No abstract available.
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Functional characteristics of neutral amino acid transporter in opossum kidney (OK) cells

Woo JS, Park MH, Oh SO, Jung JS, Kim YK, Lee SH

  • KMID: 1554554
  • Korean J Physiol Pharmacol.
  • 1997 Apr;1(2):185-193.
The characteristics of Na+/-dependent cycloleucine uptake was investigated in OK cells with regard to substrate specificity and regulation by protein kinase C (PKC). Inhibition studies with different synthetic and natural amino acids showed...
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Effects of a Protein Synthesis Inhibitor on Hippocampal Neuronal Damage of Rats in the Ventricular Fibrillation Cardiac Arrest Model

Oh DR, Chae JS, Park SH, Kim SK, Choi SM, Park JY

  • KMID: 2100566
  • J Korean Soc Emerg Med.
  • 2000 Dec;11(4):411-420.
BACKGROUND: The goal of successful resuscitation is not only to stop the process of ischemia as soon as possible but also to overcome the secondary injury process after resuscitation, which...
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Induction of Apoptosis in Human Oral Squamous Carcinoma Cells by Extracellular Products from Pseudomonas aeruginosa

Kim GC, Kang HH, Kim HC, Kim IR, Lee MH, Koo BC, Kim DH, Min JH, Park BS

  • KMID: 1564371
  • Korean J Anat.
  • 2005 Aug;38(4):337-344.
It was reported that cancer in humans and animals infected with microbial pathogens was regressed about 100 years ago. Bacteria are able to trigger apoptosis by a variety of mechanisms...
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Adriamycin Induces Apoptosis of Human Myeloid Leukemic U937 Cells via Activation of Caspase-3 and cJun-N Terminal Kinase1(JNK1)/Stress Activated Protein Kinase(SAPK)

Choi DY, Jung BH, So HS

  • KMID: 1535333
  • Korean J Pediatr Hematol Oncol.
  • 1998 Oct;5(2):285-292.
PURPOSE: Recent studies indicate that widely used chemotherapeutic agents induce apoptosis in susceptible cells. One of the effector arms in this cell death pathway is composed of cysteine proteases belonging...
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Studies on the Antioxidative and Cytotoxic Actions of Epigallocatechin Gallate in Murine Cerebral Cortical Cell Cultures

Choi Y, Lee SM, Shin H, Cho HY, Jang SJ, Choi BK, Kim JK

  • KMID: 2018612
  • J Korean Neurosurg Soc.
  • 2002 Aug;32(2):149-155.
OBJECTIVE: Epigallocatethin gallate(EGCG) is a major green tea polyphenol and is known to have potent antioxidative and antiproliferative actions. This study is performed to investigate the antioxidative effect of EGCG...
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CD36 signaling inhibits the translation of heat shock protein 70 induced by oxidized low density lipoprotein through activation of peroxisome proliferators-activated receptor gamma

Lee KJ, Ha ES, Kim MK, Lee SH, Suh JS, Lee SH, Park KH, Park JH, Kim DJ, Kang D, Kim BC, Jeoung D, Kim YK, Kim HD, Hahn JH

Oxidized LDL (OxLDL), a causal factor in atherosclerosis, induces the expression of heat shock proteins (Hsp) in a variety of cells. In this study, we investigated the role of CD36,...
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Regulation of bcl-2 family in hydrogen peroxide-induced apoptosis in human leukemia HL-60 cells

Lee JE, Sohn JW, Lee JH, Lee KC, Son CS, Tockgo YC

  • KMID: 927133
  • Exp Mol Med.
  • 2000 Mar;32(1):42-46.
Numerous types of cells have been shown to undergo apoptosis when exposed to oxidant agent such as hydrogen peroxide. In order to understand the functional relationship between the anti- and...
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Vibrio vulnificus cytolysin induces hyperadhesiveness of pulmonary endothelial cells for neutrophils through endothelial P-selectin: a mechanism for pulmonary damage by Vibrio vulnificus cytolysin

Kim BS, Kim JS

  • KMID: 931882
  • Exp Mol Med.
  • 2002 Sep;34(4):308-312.
Vibrio vulnificus cytolysin forms transmembrane pores that are permeable to calcium ions in pulmonary endothelial cells, and has been suggested as an important virulence factor that sequestrate neutrophils primarily...
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Fas-mediated apoptosis and expression of related genes in human malignant hematopoietic cells

Kim KM, Lee KH, Hong YS, Park HY

  • KMID: 755108
  • Exp Mol Med.
  • 2000 Dec;32(4):246-254.
Fas transduces apoptotic signals upon cross-linking with the Fas ligand (FasL), which is experimentally replaced by agonistic anti-Fas monoclonal antibodies (mAb). Of eight human malignant hematopoietic cell lines...
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Therapeutic Window for Cycloheximide Treatment after Hypoxic-Ischemic Brain Injury in Neonatal Rats

Park WS, Sung DK, Kang S, Koo SH, Kim YJ, Lee JH, Chang YS, Lee M

We have previously shown that cycloheximide significantly inhibited apoptosis, and reduced ensuing cerebral infarction in a newborn rat model of cerebral hypoxiaischemia. This study was performed to determine the therapeutic...
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15-Deoxy-delta12,14-PGJ2inhibits IL-6-induced Stat3 phosphorylation in lymphocytes

Kim HJ, Rho YH, Choi SJ, Lee YH, Cheon HJ, Um JW, Sohn J, Song GG, Ji JD

  • KMID: 1056229
  • Exp Mol Med.
  • 2005 Jun;37(3):179-185.
15-deoxy-delta12,14-PGJ2(15d-PGJ2) is a natural ligand that activates the peroxisome proliferators-activated receptor (PPAR) gamma, a member of nuclear receptor family implicated in regulation of lipid metabolism and adipocyte differentiation. Recent studies...
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