- Effects of Peroxisome Proliferator-activated Receptor-gamma Agonist on Fas-mediated Apoptosis in HT-29 Cells
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Chung YW, Han DS, Kang EK, Lee JS, Lee HR, Kim JB, Park JY, Kim YS, Lee OY, Choi HS, Sohn JH, Yoo DH, Hahm JS
- KMID: 772519
- Korean J Gastroenterol.
- 2003 Jul;42(1):35-41.
BACKGROUND/AIMS: Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) plays a critical role in adipocytes differentiation and insulin sensitivity and is also related to regulation of inflammation and cell proliferation. The aim of... -
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- 15-Deoxy-delta12,14-PGJ2inhibits IL-6-induced Stat3 phosphorylation in lymphocytes
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Kim HJ, Rho YH, Choi SJ, Lee YH, Cheon HJ, Um JW, Sohn J, Song GG, Ji JD
- KMID: 1056229
- Exp Mol Med.
- 2005 Jun;37(3):179-185.
15-deoxy-delta12,14-PGJ2(15d-PGJ2) is a natural ligand that activates the peroxisome proliferators-activated receptor (PPAR) gamma, a member of nuclear receptor family implicated in regulation of lipid metabolism and adipocyte differentiation. Recent studies... -
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- Ox-LDL suppresses PMA-induced MMP-9 expression and activity through CD36-mediated activation of PPAR-gamma
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Lee KJ, Kim HA, Kim PH, Lee HS, Ma KR, Park JH, Kim DJ, Hahn JH
- KMID: 1103320
- Exp Mol Med.
- 2004 Dec;36(6):534-544.
During chronic inflammatory response, mono- cytes/macrophages produce 92-kDa matrix metalloproteinase-9 (MMP-9), which may contribute to their extravasation, migration and tissue remodeling. Activation of peroxisome proliferator- activated factor receptor-gamma (PPAR-gamma) has... -
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- ERK-1/-2 and p38 Kinase Oppositely Regulate 15-deoxy-delta(12,14)-prostaglandinJ2-Induced PPAR-gamma Activation That Mediates Dedifferentiation But Not Cyclooxygenase-2 Expression in Articular Chondrocytes
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Yoon EK, Lee WK, Lee JH, Yu SM, Hwang SG, Kim SJ
- KMID: 1785763
- J Korean Med Sci.
- 2007 Dec;22(6):1015-1021.
- doi: 10.3346/jkms.2007.22.6.1015
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a ligand-activated transcription factor and plays an important role in growth, differentiation, and inflammation in different tissues. In this study, we investigated the effects... -
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