- Clinical Aspects of Genetic Testing for Dementia
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Lee SH, Park KW
- KMID: 2338710
- J Korean Geriatr Soc.
- 2008 Mar;12(1):5-10.
Dementia is the progressive or chronic dysfunction of cortical or subcortical functions that results in complex cognitive decline and Alzheimer's disease is the most common etiology of dementia. Currently, causal... -
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- Alzheimer's Disease and Apoptosis
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Kim YH, Kim YK, Kim SH, Lee SK, Kim SS, Kim HS, Park CH, Jeong SJ, Suh YH
- KMID: 1834623
- J Korean Soc Biol Psychiatry.
- 1998 Jun;5(1):66-70.
Apoptosis is a form of cell death in which the cells shrink and exhibit nuclear chromatin condensation and DNA fragmentation, and yet maintain membrane integrity. Many lines of evidence have... -
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- Pathogenesis of Alzheimer's Dementia
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Suh YH
- KMID: 2184701
- J Korean Med Assoc.
- 2006 Aug;49(8):717-730.
- doi: 10.5124/jkma.2006.49.8.717
Alzhelmer's disease (AD) is the most common cause of dementia that arises on a neuropathological background of amyloid plaques containing betaamylold (Abeta) derived from amyloid precursor protein (APP) and tau-rich... -
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- Overexpression of N141I PS2 increases γ-secretase activity through up-regulation of Presenilin and Pen-2 in brain mitochondria of NSE/hPS2m transgenic mice
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Yun WB, Park JJ, Kim JE, Sung JE, Lee HA, Lee JH, Bae CJ, Hwang DY
- KMID: 2362917
- Lab Anim Res.
- 2016 Dec;32(4):249-256.
- doi: 10.5625/lar.2016.32.4.249
Alzheimer's disease (AD) is known to induce alterations of mitochondrial function such as elevation of oxidative stress and activation of apopotosis. The aim of this study was to investigate the... -
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