- Alzheimer's Disease and Apoptosis
-
Kim YH, Kim YK, Kim SH, Lee SK, Kim SS, Kim HS, Park CH, Jeong SJ, Suh YH
- KMID: 1834623
- J Korean Soc Biol Psychiatry.
- 1998 Jun;5(1):66-70.
Apoptosis is a form of cell death in which the cells shrink and exhibit nuclear chromatin condensation and DNA fragmentation, and yet maintain membrane integrity. Many lines of evidence have... -
- CITED
-
- Close
- SHARE
-
- Close
- Pathogenesis of Alzheimer's Dementia
-
Suh YH
- KMID: 2184701
- J Korean Med Assoc.
- 2006 Aug;49(8):717-730.
- doi: 10.5124/jkma.2006.49.8.717
Alzhelmer's disease (AD) is the most common cause of dementia that arises on a neuropathological background of amyloid plaques containing betaamylold (Abeta) derived from amyloid precursor protein (APP) and tau-rich... -
- CITED
-
- Close
- SHARE
-
- Close
- iPSC Modeling of Presenilin1 Mutation in Alzheimer's Disease with Cerebellar Ataxia
-
Li L, Roh JH, Chang EH, Lee Y, Lee S, Kim M, Koh W, Chang JW, Kim HJ, Nakanishi , Barker RA, Na DL, Song J
- KMID: 2424730
- Exp Neurobiol.
- 2018 Oct;27(5):350-364.
- doi: 10.5607/en.2018.27.5.350
Disease modeling of Alzheimer's disease (AD) has been hampered by the lack of suitable cellular models while animal models are mainly based on the overexpression of AD-related genes which often... -
- CITED
-
- Close
- SHARE
-
- Close
- Expression of the plant viral protease NIa in the brain of a mouse model of Alzheimer's disease mitigates Abeta pathology and improves cognitive function
-
Kim TK, Han HE, Kim H, Lee JE, Choi D, Park WJ, Han PL
- KMID: 1402318
- Exp Mol Med.
- 2012 Dec;44(12):740-748.
The plant viral protease, NIa, has a strict substrate specificity for the consensus sequence of Val-Xaa-His-Gln, with a scissoring property after Gln. We recently reported that NIa efficiently cleaved the... -
- CITED
-
- Close
- SHARE
-
- Close
