- Farnesylation-defective Rheb Increases Axonal Length Independently of mTORC1 Activity in Embryonic Primary Neurons
-
Choi S, Sadra A, Kang J, Ryu JR, Kim JH, Sun W, Huh SO
- KMID: 2450212
- Exp Neurobiol.
- 2019 Apr;28(2):172-182.
- doi: 10.5607/en.2019.28.2.172
Rheb (Ras homolog enriched in the brain) is a small GTPase protein that plays an important role in cell signaling for development of the neocortex through modulation of mTORC1 (mammalian-target-of-rapamycin-complex-1)... -
- CITED
-
- Close
- SHARE
-
- Close
- Inhibition of Corneal Angiogenesis by a Farnesyl Transferase Inhibitor
-
Chung SK, Lee JY, Joo CK, Kim JH
- KMID: 2205470
- J Korean Ophthalmol Soc.
- 1999 Mar;40(3):662-666.
Farnesyl transferase inhibitor(FTI) disrupt farnesylation of ras protein and thus, suppress tumor growth in vivo. The ras oncogene is thought to contribute to tumor development directly by promoting tumor cell... -
- CITED
-
- Close
- SHARE
-
- Close
- Adverse effects of farnesyltransferase inhibitors on insulin actions
-
Yi SJ, Jhun BH, Kim K
- KMID: 2394597
- J Biomed Transl Res.
- 2017 Sep;18(3):113-117.
- doi: 10.12729/jbtr.2017.18.3.113
Ras activates a series of downstream effectors, including the mitogen-activated protein kinase pathway and the Rac/Rho pathway after insulin stimulation. Mutations in Ras are found in approximately 30% of all... -
- CITED
-
- Close
- SHARE
-
- Close
- The Effect of Atorvastatin and Simvastatin on NIS Expression of the TPC-1 Cell under the Therapeutic Blood Concentrations
-
Kim TK, Jung HS, Yoon CS, Ko JH, Jun HJ, Kwon MJ, Lee SH, Kim MK, Park JH
- KMID: 2169056
- Endocrinol Metab.
- 2010 Sep;25(3):192-198.
- doi: 10.3803/EnM.2010.25.3.192
BACKGROUND: Although so many experimental trials have been done to improve the redifferentiation and responsiveness of radioiodide therapy, they have not yet yielded any satisfactory results. As statins inhibit both... -
- CITED
-
- Close
- SHARE
-
- Close
