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Effect of Pravastatin on Serum Lipids of Patient with Primary Hyperlipidemia

Yoo WS, Koh WS, Cho BY, Choi SK

A new hypolipidemic drug, pravastatin, hydroxymethylglutaryl coenzyme A reductase inhibitor was administered to 33 patients with primary hyperlipidemia, 10mg daily for 8 weeks and sequential changes of lipid profile were...
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Clinical Efficacy of Pravastatin in Patients with Hypercholesterolemia

Kim JS, Han KH, Park SW, Bang JK, Hong SK, Sohn DW, Oh BH, Lee MM, Park YB, Choi YS, Seo JD, Lee YW

BACKGROUND: This study was designed to evaluate the clinical efficacy of pravastatin, HMG-CoA reductase inhibitor, in patients with hypercholesterolemia. Methods and RESULTS: Pravastatin 5 mg was administered twice daily for 12...
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Long-term hypolipidemic effect and safety of pravastatin compared with cessation of therapy in patients with hyperlipidemia

Kim SH, Kim YS, Kang HS, Cho JW, Kim KS, Kim MS, Song JS, Bae JH

BACKGROUND: Hyperlipidemia is the one of the major risk factors causing the atherosclerosis of coronary arteries. Treatment of hyperlipidemia with drugs has been confirmed the effcts of therapy showing a...
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Short-Term Hypolipidemic Effects of Pravastatin in Patients with Hyperlipidemia

Bae JH, Kang HS, Kim KS, Kim MS, Song JS

BACKGROUND: Hyperlipidemia is the one of the major risk factors causing the atherosclerosis of coronary arteries. Treatment of hyperlipidemia with drugs has been confirmed the effects of therapy showing a...
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Pravastatin-induced Stevens-Johnson syndrome

Yu JE, Choi YH, Jeong J, Cho KM, Koh YI

Stevens-Johnson syndrome (SJS) manifests with severe cutaneous reactions, most commonly triggered by medications, which are characterized by fever and mucocutaneous lesions leading to necrosis and sloughing of the epidermis. To...
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Effects of short-term pravastatin therapy in patients with hyperlipidemia

Park JW, Ryu KH, Lim CY, Koh YB, Lee Y

BACKGROUND: Pravastatin, HMG-CoA reductase inhibitor, has been known to be the most effective drug in patients with hypercholesterolemia. We studied the effectiveness and side effects of this drug. METHODS: We...
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The Effect of Pravastatin on Insulin Resistance in Hyperglycemic Patients

Jeong YJ, Kim JM, Jang SJ, Bang JH, Jung YG, Kim ST, Kang SH, Choi JI, Kim SS, Kang MY

BACKGROUND: The effect of pravastatin on insulin resistance (IR) is controversial and poorly studied in prediabetes. METHODS: This study was performed in hyperglycemic patients at Saint Carollo Hospital from January 1,...
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Efficacy of Pravastatin Monotherapy in Patients with Hypercholesterolemia

Kim JJ, Song JK, Park SW, Park SK, Park SJ, Lee SJ

BACKGROUND: The HMG-CoA reductase inhibitor is the most powerful cholesterol lowering drug and lovastatin, simvastatin and pravastatin are used clinically. We studied the efficacy and side effects of pravastatin monotherapy...
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Effect of Pravastatin Monotherapy in Patients with Hypercholesterolemia

Kim HS, Lim SW, Yoon YS, Chung NS, Shim WH, Cho SY, Kim SS

BACKGROUND: HMG-CoA reductase is known as a rate limiting enzyme in the synthesis of cholesterol. We studied the clinical efficacy and the side effects of pravastatin, a HMG-CoA reductase inhibitor,...
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Appropriate candidates for statin use in heart failure

Seo HS

No abstract available.
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Clinical Efficacy of Pravastatin(Mevalotin(R)) in Patients with Hypercholesterolemia

Shin YK, Shin YW, Lee DI, Shin JA, Moon CH, Chun KJ

An open clinical trial was performed to test the efficacy and side effects of Pravastatin(Mevlotin(R)), HMG-CoA reductase inhibitor, administering 5mg twice daily for 12weeks in 30 patients of hypercholesterolemia in...
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Effects of Pravastatin(Mevalotin(R)) on Hyperlipidemia

Suh SK, Rhee KJ

Effects of Pravastatin(Mevalotin(R)), a new HMG-CoA reductase inhibitor on the blood lipids were studied for the period of 3 months in 40 subjects with hypercholesterolemia more than 250mg/dl. Age of...
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Effect of the anti-IL-17 antibody on allergic inflammation in an obesity-related asthma model

Liang L, Hur J, Kang JY, Rhee CK, Kim YK, Lee SY

BACKGROUND/AIMS: The co-occurrence of obesity aggravates asthma symptoms. Diet-induced obesity increases helper T cell (TH) 17 cell differentiation in adipose tissue and the spleen. The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor pravastatin...
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A Clinical Trial of Pravastatin in Korean Patients with Hypercholesterolemia

Park JH, Ahn YG, Jeong MH, Cho JG, Park JC, Choi KC, Kang JC

Hypercholesterolemia is one of the major risk factors for atherosclerosis. Reduction of serum total and low density lipoprotein cholesterol(LDL-C) and the increase of high density lipoprotein cholesterol(HDL-C) are known to...
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Effects of intensive versus mild lipid lowering by statins in patients with ischemic congestive heart failure: Korean Pitavastatin Heart Failure (SAPHIRE) study

Lee HY, Cho HJ, Kim HY, Jeon HK, Shin JH, Kang SM, Baek SH

BACKGROUND/AIMS: This study was designed to evaluate the dose-effect relationship of statins in patients with ischemic congestive heart failure (CHF), since the role of statins in CHF remains unclear. METHODS: The...
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Influence of HMG-CoA Reductase Inhibitors on Bone Mass in Postmenopausal Women

Lee SY, Kim YJ

  • KMID: 2294818
  • J Korean Acad Fam Med.
  • 2003 May;24(5):451-455.
BACKGROUNG: It is controversial whether the use of HMG CoA reductase inhibitors (statins) is associated with an increased bone mineral density (BMD) in humans. The purpose of this study was...
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Efficacy of Moderate Intensity Statins in the Treatment of Dyslipidemia in Korean Patients with Type 2 Diabetes Mellitus

Kong SH, Koo BK, Moon MK

BACKGROUND: There has been evidences of ethnic differences in the low density lipoprotein cholesterol (LDL-C) lowering effect of statin. We aimed to evaluate the efficacy of moderate-intensity statins in the...
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Impact of Statin Treatment on Strut Coverage after Drug-Eluting Stent Implantation

Suh Y, Kim BK, Shin DH, Kim JS, Ko YG, Choi D, Jang Y, Hong MK

PURPOSE: To evaluate the effect of statin treatment on strut coverage after drug-eluting stent (DES) implantation. MATERIALS AND METHODS: In this study, 60 patients were randomly assigned to undergo sirolimus-eluting stent...
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HMG CoA Reductase Inhibitors Inhibit HCV RNA Replication of HCV Genotype 1b but Not 2a

Chang KS, Jo HJ

Replication of hepatitis C virus (HCV) is regulated by statin, one of 3-hydroxy-3-methylglutaryl CoA reducatase (HMG CoA reductase) inhibitors that block mevalonate pathway and cholesterol biosyntheis, which has been used...
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Cholesterol Lowering Effects of Low-dose Statins in Korean Patients

Kwon JE, Kim Y, Hyun S, Won H, Shin SY, Lee KJ, Kim SW, Kim TH, Kim CJ

OBJECTIVE: The aim of this study is to compare cholesterol lowering effects of low dose 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) in Korean patients. METHODS: A total of 909 consecutive patients...
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