- A Novel, Potent, Small Molecule AKT Inhibitor Exhibits Efficacy against Lung Cancer Cells In Vitro
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Dinavahi S, Prasanna R, Dharmarajan S, Perumal Y, Viswanadha S
- KMID: 2403412
- Cancer Res Treat.
- 2015 Oct;47(4):913-920.
- doi: 10.4143/crt.2014.057
PURPOSE: Anomalies of Akt regulation, including overexpression in lung cancer, impart resistance to conventional chemotherapy and radiation, thereby implicating this kinase as a therapeutic intervention point. A novel scaffold of... -
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