- The Effect of Low-Level Laser Irradiation on Activities of Dorsal Horn Neurons in Rats with Experimental Muscle Pain
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Sohn MK, Yoon YS, Lee SH, Kang SK, Kim BO, Sohn JH
- KMID: 2324267
- J Korean Acad Rehabil Med.
- 2005 Oct;29(5):513-520.
OBJECTIVE: This study was performed to investigate the effects of low-level laser irradiation on the dorsal horn cell activities in the rats with experimental muscle pain. METHOD: Experimental muscle pain... -
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- Zn2+ modulates the responses of rat dorsal horn neuron to C-fiber stimulation and excitatory amino acids
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Ahn CH, Shin HK, Kim JH
- KMID: 1581023
- Korean J Physiol Pharmacol.
- 2000 Dec;4(6):455-461.
Zinc contained in the neurons of central nervous system is activity-dependently released and then attenuates NMDA (N-methyl-D-aspartate)-induced neurotoxicity while augmenting non-NMDA-induced neurodegeneration. Zinc also has been reported to produce antinociceptive action on the inflammation-... -
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- Effects of capsaicin on the c-fos Protein-like immunoreactivities in the spinal cord and substance P- and CGRP-like immunoreactivities in the dorsal root ganglia of the experimental arthritic rat model
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Lee WT, Lee JK, Kang EJ, Lee JE, Park KA
- KMID: 1530626
- Korean J Anat.
- 1999 Dec;32(6):761-773.
To analyze the effects of capsaicin administered to the arthritic rat model, immunohistochemical stains for c-fos protein in the spinal dorsal horn and for substance P and CGRP in the... -
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- Epidural Morphine Block for Chronic Pain
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Choi CR, Kim Y, Hwang JH, Ahn MS
- KMID: 2187348
- J Korean Neurosurg Soc.
- 1983 Sep;12(3):369-374.
Epidural injection of 2-4mg morphine for 7-14 days were given to 18 patients with severe chronic pain. All cases except 2 arachnoiditis had considerable amelioration of pain, which commenced within... -
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- Studies on the Morphological Changes of Neurons in Dorsal Root Ganglion and Spinal Dorsal Horn of the Rat with an Experimental Peripheral Neuropathy
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Lee WT, Son MG, Jung GS, Lee HS, Park GA
- KMID: 2030728
- Korean J Anat.
- 1997 Oct;30(5):495-510.
Animal models for human chronic pain syndromes were developed and widely used for pain research. One of thsese neuropathic pain model by Kim and Chung[1992] has many advantages for operation... -
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- Effects of somatostatin and morphine on the responses of dorsal horn neurons to noxious peripheral nerve stimulation in cats
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Seo DW, Hong SB, Lee KH, Chung SJ, Kim J, Sung HK
- KMID: 1536890
- J Korean Neurol Assoc.
- 1997 Oct;15(5):1102-1116.
Painful nociceptive informations are well known to be transferred from nociceptors through spinal dorsal horn not only in different pathways but also in diverse nature depending on the type of... -
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- Effects of NO Synthase Inhibitor on Responsiveness of Dorsal Horn Neurons in Neuropathic Pain Animal Model
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Leem JW, Gwak YS, Chung SS, Lee KR, Yoon DM, Nam TS
- KMID: 2335877
- J Korean Pain Soc.
- 2000 Jun;13(1):19-30.
BACKGROUND: Partial nerve injury to a peripheral nerve may induce the development of neuropathic pain which is characterized by symptams such as spontaneous burning pain, allodynia and hyperalgesia. Though underlying mechanism has... -
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- Expression of protein kinase C-gamma mRNA on the spinal cord in a rat model of neuropathic pain
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Rhyu IJ, Na HS, Sung B, Kang YH, Kim H, Suh YS
- KMID: 1530627
- Korean J Anat.
- 1999 Dec;32(6):775-778.
Partial peripheral nerve injury occasionally results in neuropathic pain, including spontaneous burning pain and increased sensitivity to sensory stimuli such as hyperalgesia and allodynia. The pathophysiological mechanisms underlying this disease... -
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- Involvement of NMDA Receptor and L-type Calcium Channel in the Excitatory Action of Morphine
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Koo BS, Shin HK, Kang SH, Jun JH
- KMID: 2285258
- Korean J Physiol Pharmacol.
- 2002 Oct;6(5):241-246.
We studied the excitatory action of morphine on the responses of dorsal horn neuron to iontophoretic application of excitatory amino acid and C-fiber stimulation by using the in vivo electrophysiological... -
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- Calcium modulates excitatory amino acid (EAA)- and substance P-induced rat dorsal horn cell responses
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Shin HK, Kang SH, Chung ID, Kim KS
- KMID: 1917068
- Korean J Physiol Pharmacol.
- 1999 Feb;3(1):35-45.
Excitatory amino acid (EAA) and substance P (SP) have been known to be primary candidates for nociceptive neurotransmitter in the spinal cord, and calcium ions are implicated in processing of the sensory informations... -
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- Morphine-induced Modulation of Nociceptive Spinal Dorsal Horn Neuronal Activities after Formalin-induced Inflammatory Pain
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Park JM, Li KW, Jung SJ, Kim J, Kim SJ
- KMID: 2285313
- Korean J Physiol Pharmacol.
- 2005 Apr;9(2):77-86.
In this study, we examined the morphine-induced modulation of the nociceptive spinal dorsal horn neuronal activities before and after formalin-induced inflammatory pain. Intradermal injection of formalin induced time-dependent changes in... -
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- Pathophysiology of Pin
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Choe H
- KMID: 2347826
- J Korean Med Assoc.
- 2001 Dec;44(12):1277-1283.
- doi: 10.5124/jkma.2001.44.12.1277
According to the International Association for the Study of Pain (IASP), pain is un unpleasant sensory and emotional experience signaling the presence of actual or potential tissue damage, or described... -
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- Caudal Morphine for Postoperative Pain Control after Abdominal Surgery
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Woo NS, Yoon DM, Oh HK
- KMID: 1946641
- J Korean Pain Soc.
- 1988 Jun;1(1):74-79.
Caudal narcotic analgesia was assessed after the injection of 3mg morphine diluted in 80 ml (phyaiologic) saline into the sacral canal in 15 patients after upper abdominal surgery, in 20... -
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- Dopaminergic inhibition of dorsal horn cell activity in the cat
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Kim KC, Shin HK, Kim KS
- KMID: 2071824
- Korean J Physiol Pharmacol.
- 1998 Dec;2(6):661-670.
Dopamine has been generally known to exert antinociceptive action in behavioral pain test, such as tail flick and hot plate test, but there appears to be a great variance in the reports... -
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- Effects of Spinal Cord Stimulation and Adenosine on Responsiveness of Dorsal Horn Neurons in Neuropathic Rats
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Lim YJ, Lee SC, Kim DK, Kim J, Kim YC
- KMID: 1936042
- Korean J Anesthesiol.
- 2002 Jul;43(1):107-113.
- doi: 10.4097/kjae.2002.43.1.107
BACKGROUND: The aim of the present study was to investigate the effect of spinal cord stimulation (SCS) on the electrically evoked responses of the dorsal horn neuron. An additional... -
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- Caudal Morphine for Postoperative Pain Control after Abdominal Surgery
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Woo NS, Yoon DM, Oh HK
- KMID: 2237199
- Korean J Anesthesiol.
- 1981 Sep;14(3):283-288.
Caudal narcotic analgesia was assessed after the injection of 3mg morphine diluted in 30ml(physiologic) saline into the sacral canal in 15 patients after upper abdominal surgery, in 20 patients... -
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- The Role of NMDA and non-NMDA Receptors for cFos Protein Expression on the Spinal Cord in Formalin Pain Model
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Shim DM, Song HH, Kim TG, Cha SH
- KMID: 2199151
- J Korean Orthop Res Soc.
- 2000 Apr;3(1):57-70.
The purpose of this study was to evaluate effect of NMDA and non-NMDA receptor antagonists on pain-related behavioral change and cFos-like protein expression on the spinal dorsal horn neurons following... -
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- Magnesium suppresses the responses of dorsal horn cell to noxious stimuli in the rat
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Shin HK, Kim JH, Kim KS
- KMID: 2285217
- Korean J Physiol Pharmacol.
- 1999 Jun;3(3):237-244.
Magnesium ion is known to selectively block the N-methyl-D-aspartate (NMDA)-induced responses and to have anticonvulsive action, neuroprotective effect and antinociceptive action in the behavioral test. In this study, we investigated the effect of... -
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- Loss of the Spinal GABAergic System Is Involved in Chronic Central Pain Following a Spinal Cord Injury; Behavioral and Electrophysiological Evidences
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Gwak YS, Shim B, Yoon DM, Nam TS, Paik KS, Leem JW
- KMID: 2091694
- Korean J Anesthesiol.
- 2002 May;42(5):667-676.
- doi: 10.4097/kjae.2002.42.5.667
BACKGROUND: Allodynia, hyperalgesia, and spontaneous pain are symptoms characterized by chronic central pain which was frequently observed following a spinal cord injury (SCI). However, the underlying mechanism has not been... -
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- Antagonists of NMDA Receptor, Calcium Channel and Protein Kinase C Potentiate Inhibitory Action of Morphine on Responses of Rat Dorsal Horn Neuron
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Shin HK, Kim YS, Jun JH, Lee SE, Kim JH
- KMID: 1517040
- Korean J Physiol Pharmacol.
- 2003 Oct;7(5):251-254.
he present study was designed to examine whether the co-application of morphine with Ca2+ channel antagonist (Mn2+, verapamil), N-methyl-D-aspartate (NMDA) receptor antagonist (2-amino-5-phosphonopentanoic acid[AP5], Mg2+) or protein kinase C inhibitor... -
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