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A successful application of adult polymyxin B-immobilized fiber column hemoperfusion to a neonate with septic shock

Kim YA, Kim H, Kim YM, Park SE

Direct hemoperfusion therapy with a polymyxin B-immobilized fiber column (PMX-HP) has been introduced as a therapeutic option for gram negative bacterial septic shock in adults. However, its use in neonates...
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Periocular Allergic Contact Dermatitis Associated with the Use of Ofloxacin Ophthalmic Ointment: A Case Report

Jo JW, Jeong HB, Shin YB, Kang KR, Kim CY

  • KMID: 2437056
  • Korean J Dermatol.
  • 2018 Dec;56(10):624-627.
Allergic contact dermatitis is an inflammatory condition associated with periorbital erythema, edema, and pruritus. The periorbital skin is relatively thin compared with the skin over other facial areas; therefore, it...
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Use of Polymyxin B Hemoperfusion in a Patient with Septic Shock and Septic Cardiomyopathy Who Was Placed on Extracorporeal Membrane Oxygen Support

Shin SH, Lee H, Choi AJ, Chang KH, Suh GY, Chung CR

Although shock in sepsis is usually managed successfully by conventional medical treatment, a subset of cases do not respond and may require salvage therapies such as veno-arterial extracorporeal membrane oxygenation...
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Refractory Septic Shock Treated with Nephrectomy under the Support of Extracorporeal Membrane Oxygenation

Lee YK, Ryu JA, Yang JH, Park CM, Suh GY, Jeon K, Chung CR

Conventional medical therapies have not been very successful in treating adults with refractory septic shock. The effects of direct hemoperfusion using polymyxin B and veno-arterial extracorporeal membrane oxygenation (ECMO) for...
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Polymyxin B Hemoperfusion in Pneumonic Septic Shock Caused by Gram-Negative Bacteria

Yoo JW, Park SY, Jeon J, Huh JW, Lim CM, Koh Y, Hong SB

Severe sepsis and septic shock are the main causes of death in critically ill patients. Early detection and appropriate treatment according to guidelines are crucial for achieving favorable outcomes. Endotoxin...
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Polymyxin B Immobilized Fiber Hemoperfusion in Refractory Intra-abdominal Septic Shock

Chang HW, Cho YJ, Park SH, Kim M

The effects of direct hemoperfusion with polymyxin B immobilized fiber (PMX) treatment for septic shock have been recently reported. However, little evidence of a true benefit on clinical outcomes, including...
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Peptidoglycan Up-Regulates CXCL8 Expression via Multiple Pathways in Monocytes/Macrophages

Lee CW, Chung SW, Bae MJ, Song S, Kim SP, Kim K

Peptidoglycan (PG), the gram positive bacterial pathogen-associated molecular patterns (PAMP), is detected in a high proportion in macrophage-rich atheromatous regions, and expression of chemokine CXCL8, which triggers monocyte arrest on...
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Multidrug-resistant Acinetobacter baumannii infection in intensive care unit patients in a hospital with building construction: is there an association?

Kamalbeik , Talaie H, Mahdavinejad A, Karimi A, Salimi A

BACKGROUND: Acinetobacter baumannii (A. baumannii) has emerged globally as a significant pathogen in hospitals. It is also present in soil and water. In a previous study, we discovered that the...
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Induction of IL-6 and IL-8 Expression by Leptin Treatment in Periodontal Ligament Cells and Gingival Fibroblasts

Park HG, Kim JH, Cha JH, Bak EJ, Yoo YJ

  • KMID: 1431098
  • Int J Oral Biol.
  • 2013 Jun;38(2):73-80.
Leptin is one of the adipocytokines produced from adipose tissue but its functions in periodontal tissue have not previously been investigated. In our current study, we examined the effects of...
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Effect of globular adiponectin on interleukin-6 and interleukin-8 expression in periodontal ligament and gingival fibroblasts

Park HG, Bak EJ, Kim JH, Lee YS, Choi SH, Cha JH, Yoo YJ

PURPOSE: Globular adiponectin (gAd) is a type of adipocytokine, which is mainly produced by adipose tissue. It has been reported that gAd acts as a pro- as well as an...
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Allergic Contact Dermatitis on the Periorbital Area: Report of Three Cases

Lee HB, Chung BY, Ahn I, Kim H, Park CW, Lee CH

  • KMID: 1455000
  • Korean J Dermatol.
  • 2010 May;48(5):429-434.
The use of ophthalmic drugs and contact lens solutions has increased and allergic contact dermatitis due to these agents has also recently increased. The first case was a 67-year-old female...
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Dendritic Cell Activation by Glucan Isolated from Umbilicaria Esculenta

Kim HS, Kim JY, Lee HK, Kim MS, Lee SR, Kang JS, Kim HM, Lee KA, Hong JT, Kim Y, Han SB

BACKGROUND: Lichen-derived glucans have been known to stimulate the functions of immune cells. However, immunostimulatory activity of glucan obtained from edible lichen, Umbilicaria esculenta, has not been reported. Thus we...
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Susceptibility of Clinical Isolates of Acinetobacter baumannii and Pseudomonas aeruginosa to Colistin and Polymyxin B in Korea

Song W, Lee TJ, Park MJ, Kim HS, Kim JS, Woo HJ, Lee KM

  • KMID: 2285066
  • Infect Chemother.
  • 2006 Dec;38(6):362-366.
BACKGROUND: The emergence of multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa has become a major problem. The use of nontraditional agents such as colistin and polymyxin B have been tried. The...
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Mutant Prevention Concentration of Polymyxin B for the Clinical Isolates of Pseudomonas aeruginosa

Choi CU, Seo MR, Lim YH, Pai H

  • KMID: 2285063
  • Infect Chemother.
  • 2006 Dec;38(6):344-348.
BACKGROUND: Infection caused by multi-drug resistant (MDR) Gram-negative organisms such as Pseudomonas and Acinetobacter species is one of emerging important problems in modern hospitals. To treat multi-drug resistant non-fermenting Gram-negatives,...
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A Case of Allergic Contact Dermatitis to Ophthalmic Ointment

Lee CH, Park CW, Shin KY, Lee JY

  • KMID: 1791305
  • Korean J Dermatol.
  • 1999 Jul;37(7):969-971.
Neomycin is one of the aminoglycoside antibiotics and not uncommonly causes allergic contact dermatitis. Wool alcohol is one of the most widely used lanolin bases and rarely has been reported...
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The Myocardial Protective Effect and Change of the Monophasic Action Potential Duration by Adenosine Receptor, Protein Kinase C and KATP Channel in Ischemic Preconditioning in Cats

Park JS, Seok JH, Shin DG, Kim YJ, Shim BS, Kim YH

BACKGROUND AND OBJECTIVES: The myocardial protective effect of ischemic preconditioning is well known. However, the mechanism is remains unclear. The purpose of this study is to determine the role of...
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Isolation of Microorganisms and Effectiveness of Sterilization from Aortic Valve Allografts

Choi YS

  • KMID: 2089497
  • Korean J Clin Pathol.
  • 1998 Jun;18(2):156-160.
BACKGROUND: All allografted heart valves procured from brain dead multiorgan donors should be considered contaminated. If propriety procurement, disinfection and storage of allografted heart valves are done, it allows significantly...
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Induction of proliferation in resting B-cells by a factor released by activated mouse spleen cells

Puri N, Saxena RK

  • KMID: 755009
  • Exp Mol Med.
  • 1998 Dec;30(4):199-204.
Mouse spleen cells activated in a mixed lymphocyte reaction release a soluble factor, which induces a significant proliferative response in fresh mouse spleen cells. This proliferation inducing factor (PIF) was...
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Identification of a Lymphocyte Mitogenic Factor Produced by Actinobacillus actinomycetemcomitans

Seo SY, Jeong SJ, Yoo SH, Park SM, Jeong MH, Yee ST, Kim JM, Song JM, Jo WS, Lee SH

  • KMID: 2099300
  • J Korean Soc Microbiol.
  • 1998 Oct;33(5):521-535.
Actinobacillus actinomycetemcomitans, a gram-negative, capnophiTic bacterium, is associated with several human diseases including periodontal disease. Products of A. actinomycetemcomitans exert immunomodulatory effects on various lymphoid populations, some of which may...
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Nitric Oxide Synthesis in Murine Peritoneal Macrophages by Antithrombin III

Kwak JY, Park SY, Lee HS, Sohn MH, Yim CY

  • KMID: 2143381
  • Korean J Hematol.
  • 1997 Aug;32(2):234-247.
BACKGROUND: During the development of inflammatory responses, various cytokines including interferon-gamma (IFN-gamma), tumor necrosis factor-alpha (TNF), interleukin-1 (IL-1) which activate macrophages to synthesize nitric oxide (NO) and hemostatic cascades are...
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