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Influence of Methylenetetrahydrofolate Reductase C677T Polymorphism on the Risk of Lung Cancer and the Clinical Response to Platinum-Based Chemotherapy for Advanced Non-Small Cell Lung Cancer: An Updated Meta-Analysis

Zhu N, Gong Y, He J, Xia J, Chen X

PURPOSE: Methylenetetrahydrofolate reductase (MTHFR) has been implicated in lung cancer risk and response to platinum-based chemotherapy in advanced non-small cell lung cancer (NSCLC). However, the results are controversial. We performed...
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Alpha-Adducin Gly460Trp Polymorphism and Essential Hypertension in Korea

Shin MH, Chung EK, Kim HN, Park KS, Nam HS, Kweon SS, Choi JS

Previous studies have suggested that the Gly460Trp polymorphism of the alpha-adducin gene (ADD-1) is associated with salt sensitivity and primary hypertension. The results of linkage or association studies of ADD-1...
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Update on Recent Advances in the Management of Aspirin Exacerbated Respiratory Disease

Palikhe NS, Kim JH, Park HS

Aspirin intolerant asthma (AIA) is frequently characterized as an aspirin (ASA)-exacerbated respiratory disease (AERD). It is a clinical syndrome associated with chronic severe inflammation in the upper and lower airways...
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