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Alternative Polyadenylation in Human Diseases

Chang JW, Yeh HS, Yong J

Varying length of messenger RNA (mRNA) 3′-untranslated region is generated by alternating the usage of polyadenylation sites during pre-mRNA processing. It is prevalent through all eukaryotes and has emerged as...
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Conservation of cis-Regulatory Element Controlling Timely Translation in the 3'-UTR of Selected Mammalian Maternal Transcripts

Lee HJ, Lim Y, Chang SH, Min K, Han CT, Hwang SY

  • KMID: 2166279
  • Genomics Inform.
  • 2007 Dec;5(4):174-178.
The earliest stages of mammalian embryogenesis are governed by the activity of maternally inherited transcripts and proteins. Cytoplasmic polyadenylation of selected maternal mRNA has been reported to be a major...
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Neuronal RNA granule contains ApCPEB1, a novel cytoplasmic polyadenylation element binding protein, in Aplysia sensory neuron

Chae YS, Lee SH, Cheang YH, Lee N, Rim YS, Jang DJ, Kaang BK

The cytoplasmic polyadenylation element (CPE)-binding protein (CPEB) binds to CPE containing mRNAs on their 3' untranslated regions (3'UTRs). This RNA binding protein comes out many important tasks, especially in learning...
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mTOR-coordinated Post-Transcriptional Gene Regulations: from Fundamental to Pathogenic Insights

Yeh HS, Yong J

Post-transcriptional regulations of mRNA transcripts such as alternative splicing and alternative polyadenylation can affect the expression of genes without changing the transcript levels. Recent studies have demonstrated that these post-transcriptional...
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5' and 3' cis-Acting RNA Elements Required for RNA Replication of Porcine Reproductive and Respiratory Syndrome Virus

Kang SY, Choi YJ, Yun SI, Song BH, Lee YM

Porcine reproductive and respiratory syndrome virus (PRRSV), a member of the genus Arterivirus in the family Arteriviridae, is the most important viral pathogens in swine industry worldwide. Here, we have...
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Expression of Exon 1 and 6 of Indulin-like Growth Factor - 1 (IGF - 1) Gene in Thyroid Tissues

Kim SW, Chang HH, Jung IK, Woo JT, Yang IM, Kim JW, Kim SS, Choi YK

  • KMID: 2461651
  • J Korean Soc Endocrinol.
  • 1996 Dec;11(4):409-417.
Background: Goiter has been a common problem in the thyroid disease. The exact mechanism of goiter had not been clarified yet, but some goiters were increased with TSH(thyrotropin releasing hormone)...
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Construction of Recombinant p53 Adenovirus ( Ad5CMVp53 ) for Cervical Cancer Gene Therapy

An WS, Han YJ, Cho SD, Kim JW, Lee JM, Namkoong S, Kim SJ, Kim JK, Park YS, Yang JM, Park SH

  • KMID: 2260966
  • Korean J Obstet Gynecol.
  • 1998 May;41(5):1384-1392.
Human papillomavirus (HPV) has been identified in the majority of invasive cervical cancer patient and has been found to contribute in a significant way to the genesis of human cervical...
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Incidence and Causes of Hypereosinophilia in the Patients of a University Hospital

Kim DW, Shin MG, Yun HK, Kim SH, Shin JH, Suh SP, Ryang DW

BACKGROUND: Eosinophilia may be associated with various primary and reactive conditions. The incidence and the causes of eosinophilia might have been changed according to the changes in the incidence of...
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