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Chemical ejaculation using physostigmine in anejaculatory spinal cord injury patients

Kim SC, Park WH

  • KMID: 1913176
  • Korean J Urol.
  • 1993 Jun;34(3):523-527.
We tried subcutaneous physostigmine 31 times in 24 spinal cord injured patients who had lost ejaculatory capacity. Normal semens were obtained in 4 patients(6.7 %), subnormal semen in 1 patient(4.2...
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The Effects of Physostigmine on Arousal after Halothane Anesthesia

Lee MK, Lim SH, Shin JS

  • KMID: 2349731
  • Korean J Anesthesiol.
  • 1985 Sep;18(3):249-256.
Physostigmine, by inhibiting the acetylcholinesterase, leads to accumulation of acetylcholine and hence to cholinergic stimulation at both peripheral and central receptor sites and facilitates cholinergic transmission. To investigats the effects...
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The Effects of Physostigmine on Arousal after Laryngomicroscopic surgery

Kim JO, Lee JS, Shin SE, Kim JS, Nam YT

Physostigmine has been used to counteract somnolence or coma induced by different types of phamacological agent, such as anticholinergics, opioids, ketamine and tricyclic antidepressants. In this study, we have assesed...
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Postcardiotomy Central Anticholinergic Syndrome: Report of A Case

Lee JW, Kim JW, Park SI, Song MG, Choi IC, Sim JY, Kwon SU

  • KMID: 2140269
  • Korean J Thorac Cardiovasc Surg.
  • 2001 Aug;34(8):634-639.
Central anticholinergic syndrome is defined as an absolute or relative reduction in cholinergic activity in the central nervous system and has a wide variety of manifestations. It is associated with...
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The Effect of Physostigmine on Arousal and Respiration after General Anesthesia with Enflurane

Lim JJ, Um DJ, Nam YT, Kim SY

Physostigmine has been used to counteract somnolence or coma induced by different types of pharmacological agent, such as anticholinergics, opioids, ketamine, tricyclic antidepressants and inhalational anesthetics. In this study, we...
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Central Anticholinergic Syndrome Confirmed with Physostigmine after Open Heart Surgery

ParK SK, Ha SI, Jung YB, Sim JY, Lee JW, Choi IC

Central anticholinergic syndrome (CAS) can be caused by many anesthetic drugs. Early diagnosis and treatment are very important because untreated CAS may result in a life-threatening condition. Physostigmine,...
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A Case of Seizure in Diphenhydramine Overdose

Park JS, Kim H, Lee SW

  • KMID: 2101619
  • J Korean Soc Clin Toxicol.
  • 2009 Jun;7(1):23-25.
A 21-year-old woman ingested 1,250 mg of diphenhydramine in a single overdose. Diphenhydramine, a rare ingredient in over-the-counter medication, is used to treat insomnia in Korea. Toxicity is usually limited...
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Cardiopulmonary Arrest Following Small Intravenous Doses of Diazepam (Valium)

Lee GY, Lee CH

Diazepam(Valium), a benzodiazepine derivative, has been widely used for the treatment of anxiety and seizures. Recently, diazepam has been used as preanesthetic medication, preparation for endoscopy, bronchoscopy, cardiac catheterization, arteriography,...
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Central Anticholinergic Syndrome by the Use of Scopolamine Patch: A case report

Cho CD

  • KMID: 1946753
  • J Korean Pain Soc.
  • 1999 Nov;12(2):250-252.
A 77-year-old male patient was admitted to the hospital with acute appendicitis and underwent emergency appendectomy under inhalation anesthesia without any complications. After the operation, the patient was placed on epidural analgesia...
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Correlative Changes of Endothelial Nitric Oxide Synthase and Choline Acetyltransferase in the Hippocampus after Exercise

Cho YK, Zi J, Choe GS, Kang HM, Kim J, Ahn H, Park C

  • KMID: 2092941
  • Korean J Anat.
  • 2008 Sep;41(3):185-192.
We found that the expression and activity of endothelial nitric oxide synthase (eNOS) is increased in the hippocampus during exercise (Moon et al., 2006). However, the upstream regulatory factor on...
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A Suspected Case of Central Anticholinergic Syndrome after N2O-O2-Propofol Anesthesia

Chung SJ, Sim JY, Choi IC, Park SI

Central anticholinergic syndrome (CAS) is the clinical picture of the central cholinergic blockade. Many drugs used in anesthesia may cause blockade of central cholinergic neurotransmission. Early diagnosis of...
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Differences between Physostigmine- and Yohimbine-induced States Are Visualized in Canonical Space Constructed from EEG during Natural Sleep-wake Cycle in Rats

Lee MG, Kim M, Roh M, Jang IS, Won SH

Although quantitative EEG parameters, such as spectral band powers, are sensitive to centrally acting drugs in dose- and time-related manners, changes of the EEG parameters are redundant. It is desirable...
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Clinical Experience with Electroejaculation in Anejaculatory Spinal Cord Injured Men Who Failed in Chemoejaculation Using Physostigmine

Choi HC, Park WH, Shim HB

  • KMID: 1913982
  • Korean J Urol.
  • 1995 Feb;36(2):206-211.
About 85-97% of patients get to lose an ejaculatory function with a little difference according to the level of spinal cord injury. Fifty eight trials of electroejaculation stimulation were performed...
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The Antinociceptive Effect of Intrathecal Anticholinesterase on the Formalin Test in Rats

Jung G, Yoon MH, Jeong SW, Kwak SH, Chung SS, Jeong CY

BACKGROUND: Spinal anticholinesterase has been shown to have an antinociceptive action to acute noxious stimuli. The purpose of this study was to determine the effect of intrathecal anticholinesterase on the...
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The Effects of Ethanol on Cholinesterase Inactivation by Organophosphorous

Choi HC, Kim JH, Ha JH, Lee KY, Kim WJ, Woo HJ, Huh CU, Son SM, Chun EJ

  • KMID: 2320290
  • Yeungnam Univ J Med.
  • 1999 Dec;16(2):326-332.
BACKGROUND: In korea the agricultural community widely uses organophosphorous, and organophosphorous poisonings are increasing every year. We compared change in activity of acetylcholinesterase and pseudocholinesterase by organophosphorous and by the interaction...
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Influence of Tacrine on Catecholamine Secretion in the Perfused Rat Adrenal Gland

Jang SJ, Yang WH, Lim DY

  • KMID: 2071582
  • Korean J Physiol Pharmacol.
  • 2002 Aug;6(4):207-214.
The present study was designed to clarify whether tacrine affects the release of catecholamines (CA) from the isolated perfused model of rat adrenal gland or not and to elucidate the...
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The Effects of Anticholinesterase Drugs on Gastric Motility

Choi HC, Kim JH, Ha JH, Lee KY, Kim WJ, Kwak DS, Kim SH, Song PH, Yeo JH

  • KMID: 2320289
  • Yeungnam Univ J Med.
  • 1999 Dec;16(2):318-325.
BACKGROUND: Anticholinesterase drug inhibits acetylcholinesterase(AChE), induce accumulation of acetylcholine(ACh) near cholinergic receptors and cholinergic stimulation. This experiment was performed to study the effects of anticholinesterase drugs on gastric motility and...
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Wasp Sting on the Eyeball

Choe GY, Chi KU

  • KMID: 1948584
  • J Korean Ophthalmol Soc.
  • 1968 Sep;9(2_3):39-42.
The authors presented two cases of wasp sting on the eyeball. In the first case the ocluar involvements following the sting of wasp on the central cornea were desquamation of...
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The History of Myasthenia Gravis

Park JW

  • KMID: 2185023
  • J Korean Neurol Assoc.
  • 2009 May;27(2):98-104.
Since Willis described 'fatigable weakness' in 1672, most physicians consider it as a kind of hysteria due to the inconsistent fluctuation of symptoms. Erb presented three cases of 'bulbal palsy'...
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Existance of cholinergic and purinergic receptor on the detrusor muscle of rat urinary bladder

Choi TS, Kwon OC, Ha JH, Lee KY, Kim WJ

This study was aimed at investigation of the stimulatory innervations on the rat urinary bladder. Detrusor muscle strips of 15 mm long were suspended in isolated muscle chambers containing 1...
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