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Major house dust mite allergen, Der p I, activates phospholipase D in human peripheral blood mononuclear cells from allergic patients: involvement of protein kinase C

Oh JW, Kim JH, Lee KS, Han JS

  • KMID: 1109304
  • Exp Mol Med.
  • 2000 Jun;32(2):67-71.
The major house-dust-mite allergen, Der p I, stimulates the phospholipase D (PLD) in peripheral blood mononuclear cells (PBMC) from allergic patients with maximal responses after 30 min exposure. At 30...
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Changes of phospholipase D activity in TNF-alpha and anti-Fas/Apo1 monoclonal antibody induced apoptosis in HL-60 and A20 cells

Kang JH, Shin IC, Han JS

  • KMID: 754983
  • Exp Mol Med.
  • 1998 Mar;30(1):21-27.
The changes of phospholipase D (PLD) activity were investigated during the courses of apoptotic process induced by tumor necrosis factor (TNF)-alpha or anti-Fas/Apo1 antibody in human premyelocyte HL-60 and murine B cell...
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The effects of cromakalim on the mediator releases from guinea pig lung mast cell activated by specific antigen-antibody reactions

Ro JY, Yim YN, Kim KH

The inhibitory effect of cromakalim on the mediator release from mast cells caused by antigenantibody reactions was in controversy with the specific antigen used. However, it has recently been observed...
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Effect of ceramide on apoptosis and phospholipase D activity in FRTL-5 thyroid cells

Park BJ, Kim JH, Han JS, Jung PM

  • KMID: 755043
  • Exp Mol Med.
  • 1999 Sep;31(3):142-150.
Ceramide, a product of sphingomyelin hydrolysis, is now recognized as an intracellular lipid messenger, which mediates the effects of extracellular agents on cellular growth, differentiation and apoptosis. Recently, ceramide has been implicated in...
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