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Inhibition of porcine pancreatic phospholipase A2 by JE-1 andlipocortin: effective binding to phosphatidylcholine

Nam KS, Choe IS, Chung TW

  • KMID: 1690361
  • Korean J Immunol.
  • 1991 Nov;13(2):225-230.
No abstract available.
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Prurigo Pigmentosa after Injection Lypolysis with Phosphatidylcholine and Deoxycholate

Yang JY, Kim SK

  • KMID: 2353449
  • Korean J Dermatol.
  • 2016 Sep;54(8):673-674.
No abstract available.
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The Concentration of Tobramycin in Cornea and Sclera After Subconjunctival Injection of Liposome-encapsulated Tobramycin in Rabbits

Kim EK, Kim HB, Lee SC

  • KMID: 2122861
  • J Korean Ophthalmol Soc.
  • 1988 Oct;29(5):809-813.
The authers investigated the effct of liposome encapsulation on the pharmacokinetics of tobramycin after subconjuctival in jnjection in rabbits. Tobramycin was encapsulated into neutral liposomes of phosphatidylcholine and cholesterol. The...
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Signal Transduction Mechanisms Mediating Surfactant Phospholipid Secretion in Isolated Type II Cell

Park SS

  • KMID: 2317983
  • Tuberc Respir Dis.
  • 1996 Apr;43(2):123-127.
Secretion of surfactant phospholipid can be stimulated by a variety of agonists acting via at least three different signal transduction mechanisms. These include the adenylate cyclase system with activation of...
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Lipidomic analysis of plasma lipids composition changes in septic mice

Ahn WG, Jung JS, Song DK

A lipidomic study on extensive plasma lipids in bacterial peritonitis (cecal ligation and puncture, CLP)-induced sepsis in mice was done at 24 h post-CLP. The effects of administration of lysophosphatidylcholine...
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Egg phospholipids exert an inhibitory effect on intestinal cholesterol absorption in mice

Lee Y, Han CY, Bae M, Park YK, Lee JY

BACKGROUND/OBJECTIVES: Consumption of cholesterol-rich foods, such as eggs, has a minimal effect on circulating cholesterol levels in healthy humans. To gain insight, we investigated whether phospholipids rich in eggs (EPL)...
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The Evaluation of Topical Anesthetic Effects of a Liposome Encapsulated Mixture of Local Anesthetics (Lipo-MLA)

Park SS, Han KS, Baek WY

BACKGROUND: This study investigated the effect of topical analgesic effects of a liposome encapsulated mixture of local anesthetics (lipo-MLA) compared with EMLA. METHODS: 3% lipo-MLA (0.5% tetracaine base, 2.5% lidocaine base)...
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Hemin inhibits lipid peroxidation induced by ascorbate/FeSO4 and 2,2'-azobis-2-amidino-propane hydrochloride (ABAP)

Jung YD, Chay KO, Song DU, Moon JS, Yang SY, Lee MW, Ahn BW

  • KMID: 2052794
  • Exp Mol Med.
  • 1997 Sep;29(3):171-175.
Hemin blocked lipid peroxidations induced by either ascorbate/FeSO4, a metal-catalyzed oxidation system, or 2,2'-azobis-2-amidino-propane hydrochloride (ABAP) which produces peroxy radicals at constant rates. Hemin at very low micromolar concentrations strongly...
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Advent of Novel Phosphatidylcholine-Associated Nonsteroidal Anti-Inflammatory Drugs with Improved Gastrointestinal Safety

Lim YJ, Dial EJ, Lichtenberger LM

  • KMID: 2053509
  • Gut Liver.
  • 2013 Jan;7(1):7-15.
The mucosa of the gastrointestinal (GI) tract exhibits hydrophobic, nonwettable properties that protect the underlying epithelium from gastric acid and other luminal toxins. These biophysical characteristics appear to be attributable...
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Ingestion Exposure to Nitrosamines in Chlorinated Drinking Water

Kim H, Han K

  • KMID: 2380153
  • Environ Health Toxicol.
  • 2011 ;26(1):e2011003.
OBJECTIVES: N-Nitrosodimethylamine (NDMA) is classified as a probable human carcinogen by the United States Environmental Protection Agency (US EPA) and is formed during the chlorination of municipal drinking water. In...
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Effect of Dexamethasone on Gene Expression of Surfactant Protein B and Surfactant Protein C

Park IS, Sohn JW, Yoon HJ, Shin DH, Park SS

  • KMID: 2318416
  • Tuberc Respir Dis.
  • 2003 Apr;54(4):439-448.
BACKGROUND: Surfactant protein B(SP-B) and surfactant protein C(SP-C) are important in accelerating surface spreading of surfactant phospholipid. The glucocorticoids accelerate the morphologic differentiation of epithelial cells into type II cells...
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Phosphatidylcholine Formula for the Treatment of Lipoma

Kim JH, Kim JB, Park HJ, Lee JS, Joh OJ, Kim HJ, Son HC, Song KY

  • KMID: 2301846
  • Korean J Dermatol.
  • 2010 Aug;48(8):672-677.
BACKGROUND: Lipomas are benign neoplasms composed of mature fat cells. Current treatments are invasive and carry the risk of scarring. For this reason, phosphatidylcholine (PPC) formula has been widely used...
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Morinda citrifolia Inhibits Both Cytosolic Ca2+-dependent Phospholipase A2 and Secretory Ca2+-dependent Phospholipase A2

Song HS, Park SH, Ko MS, Jeong JM, Sohn UD, Sim SS

This study investigated the effects of the methanol extracts of Morinda citrifolia containing numerous anthraquinone and iridoid on phospholipase A2 (PLA2) isozyme. PLA2 activity was measured using various PLA2 substrates,...
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Impact of Micellar Vehicles on in situ Intestinal Absorption Properties of Beta-Lapachone in Rats

Jang SB, Kim D, Kim SY, Park C, Jeong JH, Kuh HJ, Lee J

The aim of the present study was to examine the effect of micellar systems on the absorption of beta-lapachone (b-lap) through different intestinal segments using a single-pass rat intestinal perfusion...
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Hair Growth Promoting Potential of Phospholipids Purified from Porcine Lung Tissues

Choi SH, Moon JS, Jeon BS, Jeon YJ, Yoon BI, Lim CJ

BP201, porcine lung tissue-derived phospholipids, consists of phosphatidylcholine as a major phospholipid species. BP201 promoted hair growth after application onto the shaved backs of BALB/c and C3H mice. Its effect...
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Effect of lidocaine cntdot HCl on microviscosity of phosphatidylcholine model membrane.

Chung IK, Kim IS, Choi CH, Cho GJ, Kim JB, Son WS, Jang HO, Yun I

  • KMID: 1580811
  • Korean J Physiol Pharmacol.
  • 2000 Jun;4(3):243-251.
In order to provide a basis for studying the molecular mechanism of pharmacological action of local anesthetics and to develop a fluorescence spectroscopic method which can detect the microviscosity of native and model...
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Cytochrome P-450, Drug Metabolizing Enzymes and Arachidonic Acid Metabolism in Pig Ocular Tissues

Lee HR, Choi KR, Cho BC

  • KMID: 2205166
  • J Korean Ophthalmol Soc.
  • 1995 Dec;36(12):2095-2107.
The eye is a relatively isolated organ and tends to retain or accumulate compounds within itself. Unless the eye possesses a mechanism for detoxifying drugs and chemicals that are carried...
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Bioactive Lysophosphatidylcholine 16:0 and 18:0 Are Elevated in Lungs of Asthmatic Subjects

Yoder M, Zhuge Y, Yuan Y, Holian O, Kuo S, van Breemen R, Thomas LL, Lum H

PURPOSE: Asthma is a chronic inflammatory disease of the airways, and is associated with upregulation of phospholipase A2 (PLA2), the enzyme that hydrolyzes phosphatidylcholine, producing lysophosphatidylcholine (LPC) and free fatty...
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The Effect of Phosphatidylcholine and Deoxycholate Compound Injections to the Localized Adipose Tissue: An Experimental Study with a Murine Model

Noh Y, Heo CY

BACKGROUND: Phosphatidylcholine (PPC) and deoxycholate (DCA) compound has been recently used for the purpose of partial lipolysis and is valued for its efficacy and lower invasiveness compared to liposuction and...
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The Effect of Dexamethasone on Gene Expression and Total Amount of Surfactant Protein A

Lim BS, Sohn JW, Yang SC, Yoon HJ, Shin DH, Park SS

  • KMID: 2318372
  • Tuberc Respir Dis.
  • 2002 Apr;52(4):395-404.
BACKGROUND: Surfactant protein A (SP-A) is importanpt for regulating surfactant secretion, synthesis and recycling. However, It's regulation in vivo is unclear. SP-A has important roles in regulating surfactant met abolism...
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