- A Case of Recrrent Spontaneous Abortion Associated with Antiphospholipid Syndrome
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Nam YS, Han SY, Choi DH, Yoon TK, Cha KY
- KMID: 1930523
- Korean J Fertil Steril.
- 1998 Dec;25(3):277-280.
Antiphospholipid antibody is an immunoglobulin which may be of any class and which reacts with any phospholipid. For clinical use the definition of the term anti-phospholipid antibody is usually restricted... -
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- Lipidomic analysis of plasma lipids composition changes in septic mice
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Ahn WG, Jung JS, Song DK
- KMID: 2414264
- Korean J Physiol Pharmacol.
- 2018 Jul;22(4):399-408.
- doi: 10.4196/kjpp.2018.22.4.399
A lipidomic study on extensive plasma lipids in bacterial peritonitis (cecal ligation and puncture, CLP)-induced sepsis in mice was done at 24 h post-CLP. The effects of administration of lysophosphatidylcholine... -
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- Phospholipase D activates HIF-1-VEGF pathway via phosphatidic acid
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Han S, Huh J, Kim W, Jeong S, Min DS, Jung Y
- KMID: 2155391
- Exp Mol Med.
- 2014 Dec;46(12):e126.
- doi: 10.1038/emm.2014.86
Growth factor-stimulated phospholipase D (PLD) catalyzes the hydrolysis of phosphatidylcholine (PC), generating phosphatidic acid (PA) which may act as a second messenger during cell proliferation and survival. Therefore, PLD is... -
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- STAT3 is involved in phosphatidic acid-induced Bcl-2 expression in HeLa cells
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Choi HJ, Lee JH, Park SY, Cho JH, Han JS
- KMID: 1109432
- Exp Mol Med.
- 2009 Feb;41(2):94-101.
- doi: 10.3858/emm.2009.41.2.012
Phosphatidic acid (PA), the product of a PLD-mediated reaction, is a lipid second messenger that participates in various intracellular signaling events and is known to regulate a growing list of... -
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- The role of mapk and pkc-delta in phosphatidic acid-mediated intercellular adhesion molecule-1 expression
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Cho WS, Yoon HS, Chin BR, Baek SH
- KMID: 2005267
- J Korean Assoc Oral Maxillofac Surg.
- 2007 Oct;33(5):445-454.
BACKGROUND: Phosphatidic acid (PA), an important second messenger, is involved in inflammation. Notably, cell-cell interactions via adhesion molecules play a central role in inflammation. This thesis show that PA induces... -
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- Alteration of Oleate-Phospholipase D Activities in Some Cell Lines after Irradiation
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Kim CY, Choi MU, Choi MS
- KMID: 2006786
- J Korean Cancer Assoc.
- 1997 Dec;29(6):944-953.
PURPOSE: Phospholipase D (PLD) catalyzes the hydrolytic cleavage of terminal phosphate diester bond of glycerophopholipids to produce phosphatidic acid (PA). PLD plays an important role in signal transduction and is... -
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- Effect of TRH on Phospholipase D Activity in GH3 Cell
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Kim DS, Lee CB, Ahn YH, Kim TW, Yoon MS, Han JS
- KMID: 2199978
- J Korean Soc Endocrinol.
- 2002 Aug;17(4):465-472.
BACKGROUND: GH3 cells are a well characterized and widely used model used for the in vitro study of growth hormone (GH) secretion. Thyrotropin releasing hormone (TRH) binds to receptors ... -
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- Localization of phospholipase D genes on the human chromosome and various tissues of rat
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Roh SY, Jeon J, Uhm CS, Ryu SH, Park KW, Suh YS, Chun YH, Park SH
- KMID: 2224538
- Korean J Anat.
- 2000 Dec;33(6):763-771.
Phospholipase D (PLD) catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. A variety of signal molecules such as hormones, neurotransmitters, extracellular matrix molecules, and growth factors are known... -
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- Expressions of Phospholipase D, MMP-2, and TIMP-2 in Adenocarcinomas of the Lung
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Park JH, Lee KM, Shin JK, Park SK, Kim HK, Kim SS, Lim SD, Huh JR, Roh JY, Suh PG, Ryu SH
- KMID: 2175112
- J Korean Cancer Assoc.
- 2000 Apr;32(2):398-406.
PURPOSE: Metastatic spread depends critically upon the invasiveness of tumor cells, i.e. their ability to breach basement membranes by elaborating and secreting specific proteolytic enzymes such as gelatinase A (MMP-2). Phospholipase D... -
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- Phospholipase D, MMP-2 and TIMP-2 Expression in the Human Colorectal Cancer
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Choi DH, Park CJ, Ko BK, Nam CW, Kim KY, Kim SS, Woo YJ, Kim DH, Cho HR
- KMID: 2095623
- J Korean Surg Soc.
- 1999 Jun;56(6):848-860.
BACKGROUND: Tumor invason and metastasis are the major causes of morbidity and death for cancer patients. Metastatic spread depends critically upon the invasiveness of the tumor cells, i.e., their ability... -
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- Alteration of Phospholipase D Activity in the Rat Tissues by Irradiation
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Choi MS, Cho YJ, Choi MU
- KMID: 2196472
- J Korean Soc Ther Radiol.
- 1997 Sep;15(3):197-206.
PURPOSE: Phospholipase D (PLD) catalyzes the hydrolysis of phosphatidyl choline to phosphatidic acid (PA) and choline. Recently, PLD has been drawing much attentions and considered to be associated with cancer... -
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- Detection of SNP of Phospholipase D1 in Children with Atopic Dermatitis
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Shin SA, Park SY, Cho JW, Han JS, Oh JW, Lee HB
- KMID: 2314507
- Pediatr Allergy Respir Dis.
- 2007 Sep;17(3):173-182.
BACKGROUND: Phospholipase D (PLD) is a widely distributed enzyme that hydrolyzes phosphatidylcholine, a major phospholipids in the cell membrane, to form phosphatidic acid (PA) which acts by itself as a... -
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- Increased Expression of Phospholipase C-gamma1 Activator Protein, AHNAK in Human Lung Cancer Tissues
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Oh YJ, Park CS, Choi SY, Cheong SC, Lee SM, Hwang SC, Lee YH, Hahn MH, Lee KB, Ryu HY, Bae YS, Rhee SG
- KMID: 2318215
- Tuberc Respir Dis.
- 1999 Sep;47(3):347-355.
BACKGROUND: Phospholipase C(PLC) plays a central role in cellular signal transduction and is important in cellular growth, differentiation and transformation. There are currently ten known mammalian isozymes of PLC reported... -
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- Trp-Lys-Tyr-Met-Val-Met stimulates phagocytosis via phospho-lipase D-dependent signaling in mouse dendritic cells
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Lee HY, Kang HK, Jo EJ, Kim JI, Lee YN, Lee SH, Park YM, Ryu SH, Kwak JY, Bae YS
- KMID: 1380208
- Exp Mol Med.
- 2004 Apr;36(2):135-144.
Dendritic cells (DCs) play a key role in activating the immune response against invading pathogens as well as dying cells or tumors. Although the immune response can be initiated by... -
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