- What we know about nonsteroidal anti-inflammatory drug hypersensitivity
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Pham DL, Kim JH, Trinh TH, Park HS
- KMID: 2163498
- Korean J Intern Med.
- 2016 May;31(3):417-432.
- doi: 10.3904/kjim.2016.085
Nonsteroidal anti-inf lammatory drugs (NSAIDs) are widely prescribed for the treatment of inflammatory diseases, but their use is frequently related to hypersensitivity reactions. This review outlines our current knowledge of... -
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- Association of TLR3 gene polymorphism with IgG subclass deficiency and the severity in patients with aspirin-intolerant asthma
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Kim SH, Yang EM, Jung HM, Pham DL, Choi HN, Ban GY, Park HS
- KMID: 2346755
- Allergy Asthma Respir Dis.
- 2016 Jul;4(4):264-270.
- doi: 10.4168/aard.2016.4.4.264
PURPOSE: Toll-like receptor 3 (TLR3) recognizes to viral double-stranded RNA and is involved in antiviral defenses. A probable role of TLR3 gene variants in the pathogenesis of aspirin-intolerant asthma (AIA)... -
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- Epithelial folliculin is involved in airway inflammation in workers exposed to toluene diisocyanate
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Pham DL, Trinh TH, Ban GY, Kim SH, Park HS
- KMID: 2396800
- Exp Mol Med.
- 2017 Nov;49(11):e395.
- doi: 10.1038/emm.2017.180
Toluene diisocyanate (TDI) exposure can directly activate and damage airway epithelium. Folliculin (FLCN) is a protein expressed by human airway epithelial cells (HAECs) to maintain airway epithelial integrity and survival.... -
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- Association of autophagy related gene polymorphisms with neutrophilic airway inflammation in adult asthma
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Pham DL, Kim SH, Losol P, Yang EM, Shin YS, Ye YM, Park HS
- KMID: 2373813
- Korean J Intern Med.
- 2016 Mar;31(2):375-385.
- doi: 10.3904/kjim.2014.390
BACKGROUND/AIMS: Role of autophagy in neutrophil function and the association of autophagy and autophagy related (ATG) gene polymorphisms with asthma susceptibility were suggested. In this study, we investigated the genetic... -
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